Propofol Versus Sevoflurane Anesthesia on the Intraocular Pressure and Hemodynamics in Patient Undergoing Cyclophotocoagulation

NCT07445672 — Not applicable, Not yet recruiting, 40 participants, Sohag University

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Comparative Study Between the Effects of Propofol Versus Sevoflurane Anesthesia on the Intraocular Pressure and Hemodynamics in Patient Undergoing Cyclophotocoagulation (Cpc )Operation

Registry	NCT07445672, acronym cyclophotocoag
Status	Not yet recruiting
Phase	Not applicable
Study type	Interventional; randomized, parallel, masking: single, supportive care
Enrollment	40 (Estimated)
Sponsor	Sohag University (Other)
Conditions	Patient Cataract
Interventions	Propofol and Fentanyl administration, Sevoflurane and fentanyl administration (Drug)
Dates	start 2026-03-01 (estimated), primary completion 2026-06-10 (estimated), completion 2026-07-20 (estimated), first posted 2026-03-03, last updated 2026-03-27
Locations	1 site in Egypt

-Summary

we use two different technique of anaesthesia for anaesthesia of patient undergoining CPC operation (20 each) were comparable with regard to demographic data and hemodynamic variables, IOP. After approval by our local Ethics Committee and written informed consent, 40 ASA physical status I, II or III patients scheduled for elective CBC operations were included in this study group s anasthetized with sevofluran while group p anaesthetized with propofol with repeated measurment of intraocular pressure of the other eye to detect which method better for IOP.

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+Arms and interventions

Arm	Type	Interventions	Description
group P patient anaesthetized by propofol	Active comparator	Drug: Propofol and Fentanyl administration	glaucoma patient anaesthetized by propofol in induction and maintenance with fentanyl and cisatracurium as muscle relaxant during cyclophotocoagulation operation
Grpoup S patient anesthetized by sevoflurane	Active comparator	Drug: Sevoflurane and fentanyl administration	glaucoma patient anaesthetized by Sevoflurane in induction and maintenance with fentanyl and cisatracurium as muscle relaxant during cyclophotocoagulation operation

Propofol and Fentanyl administration (Drug): Group P patient anaesthetized by propofol and fentanyle for induction and maintenance
Sevoflurane and fentanyl administration (Drug): Group S patient anaesthetized by sevoflurane and fentanyl for induction and maintenance

+Outcome measures

Primary outcomes

measurement of Intra ocular pressure during different type of anesthesia [2 minute after administration of muscle relaxant and every 5 minute until termination of surgery]

+Eligibility

Sex: All, ages: 15 Years to 50 Years

Inclusion Criteria:

ASA I to III

Exclusion Criteria:

* known allergies; adverse reactions to any of the anesthetic agents used in the study
* unstable angina or manifest congestive heart failure.
* airway management was expected to be difficult

+Locations (1)

Facility	City	Country	Status
Suhag faculty of medicine	Sohag, Sohag Governorate	Egypt