34 completed, 17 unknown, 8 recruiting, 8 withdrawn. 28 Phase 2, 25 Not applicable, 17 Phase 4, 10 Phase 3, 6 Phase 1.
Follow Saline injection: new trials by email Literature Review of Saline injection trials Research Report on Saline injection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SCARFREE-001: Verteporfin for Scar Prevention Verteporfin Injection, Saline injection - Surgical Scar | Phase 2 | Recruiting | Odense University Hospital | 12 | 2026-10-01 | 2026-10-27 |
| Cleft Lip Scarring After Botox Botulinum Toxin Type A (BOTOX) Injection, Normal Saline - Cleft Lip, Cleft Lip Scar | Phase 2 | Recruiting | Children's National Research Institute | 40 | 2026-02-19 | 2026-10-19 |
| Phase II Clinical Trial: Multi-dosing the BCG Vaccine for Fibromyalgia Bacillus Calmette Guerin Vaccine, Saline Injection - Fibromyalgia | Phase 2 | Withdrawn | Massachusetts General Hospital | 2026-01-01 | 2024-11-21 | |
| Mesenchymal Stem Cell and Exosome Therapy for Diabetic Erectile Dysfunction Umbilical Cord-Derived Mesenchymal Stem Cells, Umblical Cord-Derived Mesenchymal Stem Cell-Derived Exosomes, Placebo Intracavernosal Injection - Erectile Dysfunction With Diabetes Mellitus | Phase 2 / Phase 3 | Recruiting | Ankara City Hospital Bilkent | 90 | 2025-12-29 | 2026-03-18 |
| Improving Vaccine Protection for Adults AS01 adjuvant (0.5 mL intramuscular), YF17D (Stamaril, Sanofi-Pasteur), Placebo (NaCl 09%, 0.5mL) - Immune System Responses and Trained Immunity After AS01 Administration, Healthy Adult | Phase 2 | Recruiting | Singapore General Hospital | 40 | 2025-11-06 | 2026-06-15 |
| A Study to Learn About How a New Pneumococcal Vaccine Works in Adults PG4 vaccine in Buffer 1 with low dose PA-001, PG4 in Buffer 1 with low dose PA-002, PG4 in Buffer 1 with high dose PA-001 - Streptococcus Pneumoniae | Phase 1 | Active not recruiting | Pfizer | 380 | 2025-07-22 | 2026-06-22 |
| Ondansetron vs. Dexamethasone for Postoperative Nausea Placebo (Normal Saline), Ondansetron (Zofran), Dexamethasone - Postoperative Nausea and Vomiting (PONV) | Phase 4 | Completed | Hafiz Muhammad Hamza | 105 | 2025-03-20 | 2025-06-17 |
| Efficacy of Intramuscular Steroid Injection for Chronic Cough. Triamcinolone Acetonide Injectable Suspension, Saline injection - Chronic Cough (CC), Laryngeal Disease | Early Phase 1 | Recruiting | Medical University of South Carolina | 40 | 2024-12-02 | 2026-07-22 |
| Comparison of the Efficacy of Ultrasound-Guided Injections of Saline, High-Concentration Dextrose, and Ligament Repair Agents for the Treatment of Medial Collateral Ligament Pathology in Degenerative Knee Osteoarthritis: A Randomized Double-Blind Trial. STABHA Injection, High-Concentration Glucose Water Injection, Saline Injection - Medial Collateral Ligament Lesions, Knee Osteoarthritis | Not applicable | Unknown | Chen Ting-an | 51 | 2024-10-01 | 2024-10-01 |
| Peripheral Nerve Injections for CRPS Triamcinolone Acetonide 40mg/mL, Saline Injection, Bupivacaine - Complex Regional Pain Syndromes | Phase 2 | Unknown | Ottawa Hospital Research Institute | 50 | 2024-05-30 | 2024-09-19 |
| Blocking of the Gut Hormone Receptor for Glucagon-like Peptide 2 (GLP-2) by the GLP-2 Receptor Antagonist GLP-2(3-33) Saline infusion, Saline injection, 1nmol antagonist infusion - Healthy | Not applicable | Completed | University of Copenhagen | 10 | 2024-05-01 | 2025-05-02 |
| Microfragmented Adipose Tissue Compared to Saline Injection for the Treatment of Knee Osteoarthritis Microfragmented Adipose Tissue derived using the Lipogems® System, Saline Injection - Knee Osteoarthritis, Osteo Arthritis Knee | Phase 3 | Active not recruiting | Lipogems International spa | 173 | 2024-03-15 | 2025-06-12 |
| Repeated Injections of i-PRF for Decreasing Root Resorption After the Orthodontic Treatment. 4-time i-PRF injection group, Saline injection - Crowding of Anterior Maxillary Teeth | Not applicable | Completed | Damascus University | 36 | 2024-01-13 | 2026-01-20 |
| FNB in Meniscal Tear Under SA Sono-guided injection, Ropivacaine injection, Saline injection - Meniscus Tear, Femoral Nerve Block | Not applicable | Unknown | Chuncheon Sacred Heart Hospital | 100 | 2023-09-18 | 2023-09-22 |
| FNB in Meniscal Tear Under GA Sono-guided injection, Ropivacaine injection, Saline injection - Meniscus Tear, Femoral Nerve Block | Not applicable | Unknown | Chuncheon Sacred Heart Hospital | 100 | 2023-09-18 | 2023-09-22 |
| FNB in ACL Recon Under GA Sono-guided injection, Ropivacaine injection, Saline injection - Anterior Cruciate Ligament Rupture, Femoral Nerve Block | Not applicable | Not yet recruiting | Chuncheon Sacred Heart Hospital | 100 | 2023-09-18 | 2023-09-22 |
| FNB in ACL Recon Under SA Sono-guided injection, Ropivacaine injection, Saline injection - Anterior Cruciate Ligament Rupture, Femoral Nerve Block | Not applicable | Not yet recruiting | Chuncheon Sacred Heart Hospital | 100 | 2023-09-18 | 2023-09-22 |
| Spinal Fusions Steroid Study Dexamethasone injection, Saline injection - Spinal Fusion | Early Phase 1 | Unknown | University of Texas at Austin | 70 | 2023-07-01 | 2023-08-22 |
| Prospective Study to Determine the Safety and Effectiveness of a Connective Tissue Allograft Active Matrix (AM) vs. Standard of Care in Arthroscopic Rotator Cuff Repair ActiveMatrix® Dosage A, ActiveMatrix® Dosage B, Saline injection - Rotator Cuff Tears | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 72 | 2023-06-14 | 2026-04-29 |
| Repeat BCG Vaccinations for the Treatment of New Onset Type 1 Diabetes in Children Age 8-<18 Years Bacillus Calmette-Guérin, Saline Injection - Diabetes Mellitus, Type 1 Diabetes | Phase 2 | Active not recruiting | Massachusetts General Hospital | 100 | 2023-05-04 | 2026-06-26 |
Showing 20 of 82. Sign in to see all of them.
Low Back Pain (5) · Diabetes Mellitus, Type 1 (4) · Osteoarthritis, Knee (4) · Pain (4) · Diabetes Mellitus (3) · Obesity (3) · Osteoarthritis (3) · Tennis Elbow (3) · Acute Pain (2) · Anterior Cruciate Ligament Injuries (2) · Back Pain (2) · Erectile Dysfunction (2) · Fasciitis, Plantar (2) · Graves Ophthalmopathy (2) · Intervertebral Disc Degeneration (2)
Chuncheon Sacred Heart Hospital (5) · Massachusetts General Hospital (4) · MiMedx Group, Inc. (3) · Emory University (2) · Odense University Hospital (2) · Ottawa Hospital Research Institute (2) · Singapore General Hospital (2) · The Jerzy Kukuczka Academy of Physical Education in Katowice (2) · University of Toronto (2) · Aalborg University (1) · Aga Khan University (1) · Ankara City Hospital Bilkent (1) · Baylor College of Medicine (1) · Benha University (1) · CHU de Quebec-Universite Laval (1)
United States (37) · Canada (8) · Denmark (5) · South Korea (5) · Finland (2) · Israel (2) · Pakistan (2) · Poland (2) · Taiwan (2) · Turkey (Türkiye) (2) · Australia (1) · Chile (1) · China (1) · Egypt (1) · Germany (1)
Denise L Faustman, MD, PhD (3) · Stuart D Miller, MD (3) · Daniel B Rootman, MSc MD (2) · Ahmad S. Burhan, DDS MSc PhD (1) · Ahmed Elsaman, PhD (1) · Alejandro D. Mesples, MD (1) · Amit Singhal, B.Sc., M.Sc., Ph.D. (1) · Angel Arnaout, MD (1) · Antti Eskelinen, M.D., Ph.D (1) · Arif Awan, MD (1) · Berthold Amann, MD (1) · Bryan D Springer, MD (1) · Candice Y.Y. Chan, MBChB, MRCP (1) · Charles W Hogue, MD (1) · Christopher P. Smith, MD (1)
PMID 10895746, PMID 11375828, PMID 11929206, PMID 11983659, PMID 15504180, PMID 16735582, PMID 17413463, PMID 18844269, PMID 19568011, PMID 20448192, PMID 21368772, PMID 21422467, PMID 21562414, PMID 22169699, PMID 22972856, PMID 23220857, PMID 23331510, PMID 23741398, PMID 23825183, PMID 24168077, PMID 24373307, PMID 24670704, PMID 24770995, PMID 25926350, PMID 26865594, PMID 28986051, PMID 29140929, PMID 29847426, PMID 30662111, PMID 32355632, PMID 32975624, PMID 33086348, PMID 33094437, PMID 34358471, PMID 34554689, PMID 34590307, PMID 34875850, PMID 36027906, PMID 36453122, PMID 39591365, PMID 39749555, PMID 42219245, PMID 42373095, PMID 937623, PMID 9505784, PMID 9706923
2018 (1), 2025 (1), K23GM128221 (1)