8 completed, 3 terminated, 2 recruiting, 2 unknown. 17 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 17 | Completed 8, Terminated 3, Recruiting 2, Unknown 2, Withdrawn 2 |
Follow Saline injection: new trials by email Literature Review of Saline injection trials Research Report on Saline injection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ondansetron vs. Dexamethasone for Postoperative Nausea Placebo (Normal Saline), Ondansetron (Zofran), Dexamethasone - Postoperative Nausea and Vomiting (PONV) | Phase 4 | Completed | Hafiz Muhammad Hamza | 105 | 2025-03-20 | 2025-06-17 |
| Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture Percutaneous needle fasciotomy, Corticosteroid injection, Saline injection - Dupuytren Contracture, Dupuytren's Disease | Phase 4 | Recruiting | Regionshospitalet Silkeborg | 400 | 2023-01-10 | 2023-05-17 |
| Body and Social Behavior Influenza vaccine, Placebo - Psychology, Social, Inflammation | Phase 4 | Completed | University of North Carolina, Chapel Hill | 104 | 2022-10-17 | 2024-11-27 |
| Saline Injections for Prophylactic Treatment of Chronic Migraine Saline injection, Placebo - Chronic Migraine | Phase 4 | Terminated | Göteborg University | 10 | 2019-06-17 | 2022-03-31 |
| Metabolic Phenotyping During Stress Hyperglycemia in Cardiac Surgery Patients Dulaglutide Injection, Saline Injection - Stress Hyperglycemia | Phase 4 | Terminated | Emory University | 28 | 2019-03-08 | 2024-05-30 |
| Effect of Liraglutide on Microbiome in Obesity Liraglutide 6 MG/ML [Saxenda], Placebo - Obesity, Weight Loss | Phase 4 | Unknown | Federico II University | 70 | 2019-01-09 | 2019-08-20 |
| Comparison of Effectiveness Between PL and PRP on Knee Osteoarthritis: a Prospective,Randomized,Placebo-controlled Trial Saline injection, PRP injection, PL injection - Osteoarthritis (OA) of the Knee | Phase 4 | Recruiting | National Taiwan University Hospital | 150 | 2018-05-15 | 2026-09-21 |
| Impact of Liraglutide 3.0 on Body Fat Distribution Liraglutide, Placebo - Obesity, Visceral, Cardiovascular Diseases | Phase 4 | Completed | University of Texas Southwestern Medical Center | 235 | 2017-01-01 | 2021-11-19 |
| The Effect of Influenza Vaccination on the Systemic Inflammatory Response and Myocardial Protection in Patients Undergoing Cardiac Surgery: a Randomized Controlled Trial Influenza Vaccine, Placebo - Systemic Inflammatory Response | Phase 4 | Completed | Health Sciences North Research Institute | 30 | 2015-09-01 | 2026-10-05 |
| The Effect of Dexmedetomidine for Suprascapular Nerve Block With Axillary Nerve Block Dexmedetomidine injection, Saline injection - Suprascapular Nerve Block, Axillary Nerve Block | Phase 4 | Completed | Chuncheon Sacred Heart Hospital | 46 | 2015-05-20 | 2020-05-21 |
| Hyaluronic Acid Gels for Upper Lid Retraction in Active Stage Thyroid Eye Disease Hyaluronic Acid Gel injection, Saline injection - Thyroid Eye Disease | Phase 4 | Terminated | University of California, Los Angeles | 2 | 2013-12-01 | 2021-10-04 |
| Study Trial of Dexamethasone Use for Alleviation of Symptoms After Scleral Buckle Eye Surgery Dexamethasone Sodium Phosphate Injection, Saline Injection - Retinal Detachment | Phase 4 | Withdrawn | University of Toronto | 2011-04-01 | 2015-06-03 | |
| Use of Botox in the Management of Thyroid Related Upper Eyelid Retraction Botulinum Toxin Type A, Saline injection - Graves Ophthalmopathy | Phase 4 | Withdrawn | University of Toronto | 2011-01-01 | 2015-06-03 | |
| The Impact of Hyaluronic Acid Injections on Osteoarthritic Knee Mechanics Hyaluronic acid, Placebo (Saline injection) - Osteoarthritis, Knee | Phase 4 | Unknown | University of Western Ontario, Canada | 30 | 2008-07-01 | 2009-04-01 |
| Durolane Compared to Saline in Patients With Unilateral Knee Osteoarthritis Durolane injection, Saline injection - Unilateral Knee Osteoarthritis | Phase 4 | Completed | Galderma R&D | 218 | 2003-02-01 | 2022-08-25 |
| Pain Relief for Thrombosed External Haemorrhoids injection of botulinum toxin, injection of saline - Thrombosed External Hemorrhoid | Phase 4 | Completed | University of Palermo | 30 | 2003-01-01 | 2008-07-18 |
| Anthrax Vaccine Clinical Trial to Assess Dose Reduction and Route Change Anthrax Vaccine Adsorbed, Saline injection - Healthy | Phase 4 | Completed | Centers for Disease Control and Prevention | 1564 | 2002-05-01 | 2024-05-29 |
Obesity (3) · Graves Ophthalmopathy (2) · Pain (2) · Vomiting (2) · Anthrax (1) · Cardiovascular Diseases (1) · Connective Tissue Diseases (1) · Contracture (1) · Dupuytren Contracture (1) · Fibroma (1) · Inflammation (1) · Joint Diseases (1) · Lipid Metabolism Disorders (1) · Musculoskeletal Diseases (1) · Nausea (1)
University of Toronto (2) · Centers for Disease Control and Prevention (1) · Chuncheon Sacred Heart Hospital (1) · Emory University (1) · Federico II University (1) · Galderma R&D (1) · Göteborg University (1) · Hafiz Muhammad Hamza (1) · Health Sciences North Research Institute (1) · National Taiwan University Hospital (1) · Regionshospitalet Silkeborg (1) · University of California, Los Angeles (1) · University of North Carolina, Chapel Hill (1) · University of Palermo (1) · University of Texas Southwestern Medical Center (1)
United States (5) · Canada (4) · Denmark (1) · Italy (1) · Pakistan (1) · South Korea (1) · Sweden (1) · Taiwan (1) · United Kingdom (1)
Daniel B Rootman, MSc MD (2) · Daniel Rootman (1) · Francisco Pasquel, MD, MPH (1) · Gaetano Di Vita (1) · Jennifer Wright, DVM (1) · Jeppe Lange, MD, PhD (1) · Joseph E DeCaria, BA, MSc('09) (1) · Jung-Taek Hwang, MD, PhD (1) · Keely Muscatell, PhD (1) · Malin Kim, MD (1) · Mark Mandelcorn, MD FRCSC (1) · Nancy Tucker, MD FRCSC (1) · Naveed Ullah Khan, Consultant surgery, HOD (1) · Nigel Arden, MD (1) · Parag Joshi, MD (1)
PMID 18844269, PMID 21368772, PMID 22169699, PMID 23741398, PMID 24168077, PMID 24373307, PMID 26865594, PMID 32975624, PMID 34358471, PMID 39749555
2018 (1), K23GM128221 (1)