8 completed, 8 unknown, 3 recruiting, 1 active not recruiting. 21 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 21 | Completed 8, Unknown 8, Recruiting 3, Active not recruiting 1, Not yet recruiting 1 |
Follow Propofol: new trials by email Literature Review of Propofol trials Research Report on Propofol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ketamine and Propofol NeuroImaging Propofol, Ketamine, Peripheral Nerve Stimulation - Anesthesia, Pain | Early Phase 1 | Recruiting | Keith M Vogt | 60 | 2026-04-10 | 2026-05-19 |
| The Efficacy and Safety of Remimazolam Besylate for Cardiac Anesthesia remimazolam besylate, propofol - Anesthesia | Early Phase 1 | Not yet recruiting | Chinese Academy of Medical Sciences, Fuwai Hospital | 320 | 2025-01-01 | 2024-12-05 |
| Effect of Propofol and Sevoflurane Anesthesia on HSP70 Expression in Tumor Cells Propofol, Sevoflurane - Anesthesia, Cancer Recurrence | Early Phase 1 | Active not recruiting | Saint Petersburg State University, Russia | 10 | 2024-10-10 | 2025-05-04 |
| Paracetamol Plus Tramadol Versus Fentanyl As Preemptive Analgesia For Enhanced Recovery After Day Case Surgeries tramadol plus paracetamol, Fentanyl, propofol and muscle relaxant (cisatracurium) - Preemptive Paracetamol Plus Tramadol and Preemptive Fentanyl | Early Phase 1 | Unknown | Zagazig University | 102 | 2024-09-01 | 2024-08-20 |
| A Study of the Correlation Between the Debilitating State of the Elderly and Propofol Sensitivity propofol - Frailty, Telomere | Early Phase 1 | Completed | Second Hospital of Shanxi Medical University | 128 | 2024-01-20 | 2025-03-11 |
| The Efficacy of Regional Scalp Block in Craniotomy nerve block with 0.5% ropivacaine, General anesthesia and opioids (fentanyl, propofol, rocuronium) - Scalp Nerve Block, Craniotomy Surgery | Early Phase 1 | Completed | Universitas Airlangga | 40 | 2023-10-01 | 2024-12-06 |
| Inhalational Anesthesia vs TIVA in Endoscopic Tympanoplasty Isoflurane Inhalant Product, Sevoflurane inhalant product, Propofol injection - Perforated Eardrum | Early Phase 1 | Unknown | Our Lady of the Lake Hospital | 100 | 2023-09-01 | 2023-11-01 |
| Sedation in Patients Undergoing GIT Endoscopy propofol and magnesium sulphate ,propofol and nalbuphine - Sedation for Patients Undergoing GIT Endoscopy | Early Phase 1 | Unknown | Assiut University | 60 | 2023-08-01 | 2023-08-16 |
| Investigation of Cerebral Motor Activity Modulations Following Median Nerve Stimulation During General Anaesthesia Propofol, Median nerve stimulation, EEG measurements - Accidental Awareness During General Anesthesia | Early Phase 1 | Recruiting | Brugmann University Hospital | 30 | 2023-01-15 | 2023-02-16 |
| Effect of Paravertebral Muscle Fat Infiltration on Rocuronium Use in Lumbar Surgery Rocuronium Bromide - Spinal Stenosis Lumbar | Early Phase 1 | Completed | Zheng Guo | 87 | 2022-10-25 | 2023-02-15 |
| Lignocaine Versus Sodium Bicarbonate on Reducing Pain During Propofol Injection Propofol Injection - Propofol Adverse Reaction | Early Phase 1 | Completed | Cairo University | 180 | 2022-08-01 | 2024-09-05 |
| Different Dose of Esketamine Inhibiting Response to Laryngeal Mask Airway Insertion Esketamine 0.2mg/kg, Esketamine 0.3mg/kg - Anesthesia | Early Phase 1 | Completed | Aerospace Center Hospital | 58 | 2022-05-01 | 2024-04-17 |
| Effects of Ciprofol Anesthesia on Learning and Memory Function and Antidepressant Effects of ECT in Depressive Patients ciprofol, Propofol - Depressive Disorder | Early Phase 1 | Unknown | First Affiliated Hospital of Chongqing Medical University | 390 | 2022-03-01 | 2022-03-04 |
| Study Comparing Local/ MAC Anesthesia in Lumbar Decompression Propofol Injection, Lidocaine Hydrochloride, Injectable - Lumbar Spinal Stenosis | Early Phase 1 | Recruiting | Stanford University | 100 | 2021-12-01 | 2026-03-20 |
| Propofol/Dexmedetomidine Versus Desflurane Effects on Post Hepatectomy Hepatocellular Injury Propofol, dexmedetomidine, Desflurane - Hepatectomy | Early Phase 1 | Unknown | Ain Shams University | 30 | 2021-06-01 | 2023-01-18 |
| The Effect of Propofol on Dexamethasone-induced Perineal Pruritus Propofol, normal saline - Pruritus | Early Phase 1 | Completed | Yangzhou University | 40 | 2020-09-01 | 2022-02-25 |
| Dexmedetomidine and Propofol in the Treatment of Emergence Agitation Dexmedetomidine, Propofol - Emergence Agitation | Early Phase 1 | Unknown | RenJi Hospital | 120 | 2019-11-01 | 2020-01-14 |
| The PATHFINDER Study: A Feasibility Trial Ropivacaine, Ketamine, Remifentanil - Coronary Artery Disease, Delirium | Early Phase 1 | Completed | Beth Israel Deaconess Medical Center | 22 | 2019-08-20 | 2021-01-28 |
| Single Bolus Dose of Ketodex Versus Ketofol For Prevention Of Emergence Agitation In Adults Undergoing Nasal Surgeries "Ketamine" and "dexmedetomidine" and "propofol" and "0.9%saline" - Agitation, Emergence | Early Phase 1 | Completed | Zagazig University | 150 | 2019-07-03 | 2019-11-27 |
| Effects of Sevoflurane and Propofol on Optic Nerve Sheath Diameter During Laparoscopic Gynecologic Surgery Sevoflurane, Propofol - Laparoscopic Gynecologic Surgery | Early Phase 1 | Unknown | Obstetrics & Gynecology Hospital of Fudan University | 110 | 2018-03-01 | 2020-06-23 |
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Emergence Delirium (2) · Coronary Artery Disease (1) · Delirium (1) · Depressive Disorder (1) · Femur Head Necrosis (1) · Frailty (1) · Neoplasms (1) · Pain (1) · Pruritus (1) · Psychomotor Agitation (1) · Spinal Stenosis (1) · Tympanic Membrane Perforation (1)
Zagazig University (2) · Aerospace Center Hospital (1) · Ain Shams University (1) · Assiut University (1) · Beth Israel Deaconess Medical Center (1) · Brugmann University Hospital (1) · Cairo University (1) · Chinese Academy of Medical Sciences, Fuwai Hospital (1) · First Affiliated Hospital of Chongqing Medical University (1) · Keith M Vogt (1) · Obstetrics & Gynecology Hospital of Fudan University (1) · Our Lady of the Lake Hospital (1) · RenJi Hospital (1) · Saint Petersburg State University, Russia (1) · Second Hospital of Shanxi Medical University (1)
China (7) · Egypt (4) · United States (4) · Belgium (1) · Indonesia (1) · Russia (1)
Balachundhar Subramaniam, MD, MPH (1) · Christijogo Soemartono Waloejo, MD, Ph.D (1) · Denis Schmartz, MD (1) · Guo Zheng, Ph. D (1) · Hamdy Abbas Youssef, Professor (1) · Hany Alzahaby, Professor (1) · Keith M Vogt, MD, PhD (1) · Khaled Tolba Younes, Lecturer (1) · Ola Mahmoud Wahba, Assistant Professor (1) · Olfat Amin, M.D (1) · Rahul Mehta, MD (1) · Todd Alamin, MD (1)
PMID 33504329, PMID 34722563, PMID 34784941, PMID 36729587
R35GM146822 (1)