7 completed, 2 unknown, 1 active not recruiting, 1 not yet recruiting. 12 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 12 | Completed 7, Unknown 2, Active not recruiting 1, Not yet recruiting 1, Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effects of Clostridium Butyricum on Adverse Events During Adjuvant Chemotherapy for Colorectal Cancer Clostridium butyricum capsules, placebo capsules - Colorectal Cancer, Chemotherapeutic Toxicity | Phase 4 | Not yet recruiting | The Affiliated Hospital of Qingdao University | 238 | 2025-10-31 | 2025-09-03 |
| Probiotics as an Adjunct to Antibiotics for Recurrent Bacterial Vaginosis Probiotic Combination Cap/Tab, Placebo capsules - Recurrent Bacterial Vaginosis | Phase 4 | Completed | Nishtar Medical University | 70 | 2025-08-01 | 2026-10-26 |
| Dual-dose Aprepitant to Reduce Postoperative Nausea and Vomiting After Laparoscopic Bariatric Surgery. Aprepitant 80 mg, Placebo - Postoperative Nausea and Vomiting, Bariatric Surgery | Phase 4 | Terminated | Insel Gruppe AG, University Hospital Bern | 71 | 2022-03-17 | 2025-02-27 |
| The Impact of Oral Vitamin C in Prevention for Post Operative Atrial Fibrillation (POAF) in Coronary Artery Bypass Surgery (CABG) Patients Vitamin C 500 MG Oral Capsule(High dose 2g daily), Vitamin C 500 MG Oral Capsule(Low-dose 1g daily), placebo capsules - Post Operative Atrial Fibrillation | Phase 4 | Unknown | Helwan University | 180 | 2020-10-13 | 2023-10-10 |
| Utility of Single-dose Oral Antibiotic Prophylaxis in Prevention of Surgical Site Infection in Dermatologic Surgery Cephalexin, Placebo capsules - Surgical Site Infection | Phase 4 | Active not recruiting | Carilion Clinic | 574 | 2020-10-01 | 2026-03-25 |
| Allopurinol in Acute Coronary Syndrome allopurinol sustained-release capsules, placebo capsules - Acute Coronary Syndrome | Phase 4 | Completed | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 162 | 2019-03-01 | 2022-09-16 |
| Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic Hypotension Droxidopa capsules, Placebo capsules - Symptomatic Neurogenic Orthostatic Hypotension | Phase 4 | Completed | H. Lundbeck A/S | 453 | 2016-02-11 | 2023-08-23 |
| Probiotics in the Prevention of Complications After Colorectal Surgery Probiotics, Placebo - Postoperative Complications | Phase 4 | Completed | Evangelos J. Giamarellos-Bourboulis, M.D. | 164 | 2013-04-01 | 2014-12-10 |
| Tongxinluo Improve High on Clopidogrel Platelet Reactivity Patients With Coronary Heart Disease Tongxinluo, placebo - Coronary Artery Disease | Phase 4 | Completed | Han Yaling | 134 | 2012-11-01 | 2015-12-23 |
| Preventing Pain After Heart Surgery Pregabalin, Ketamine infusion, Placebo capsules - Pain, Hyperalgesia | Phase 4 | Completed | Barts & The London NHS Trust | 150 | 2011-12-12 | 2024-11-05 |
| Continuous Positive Airway Pressure and Acetazolamide to Treat Sleep Apnea Syndrome Patients at Altitude acetazolamide, nocturnal continuous positive airway pressure, placebo - Obstructive Sleep Apnea Syndrome | Phase 4 | Completed | University of Zurich | 51 | 2009-06-01 | 2014-05-20 |
| Colecalciferol as an Add-on Treatment to Interferon-beta-1b for Treatment of Multiple Sclerosis (MS) Colecalciferol, Placebo capsules - Multiple Sclerosis | Phase 4 | Unknown | University of Turku | 70 | 2008-03-01 | 2011-05-19 |
Acute Coronary Syndrome (1) · Anastomotic Leak (1) · Apnea (1) · Chronic Disease (1) · Colorectal Neoplasms (1) · Coronary Artery Disease (1) · Coronary Disease (1) · Hyperalgesia (1) · Hypoxia (1) · Infections (1) · Multiple Sclerosis (1) · Multiple System Atrophy (1) · Neuralgia (1) · Pain (1) · Parkinson Disease (1)
Barts & The London NHS Trust (1) · Carilion Clinic (1) · Evangelos J. Giamarellos-Bourboulis, M.D. (1) · H. Lundbeck A/S (1) · Han Yaling (1) · Helwan University (1) · Insel Gruppe AG, University Hospital Bern (1) · Nishtar Medical University (1) · The Affiliated Hospital of Qingdao University (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1) · University of Turku (1) · University of Zurich (1)
China (3) · Switzerland (2) · United States (2) · Egypt (1) · Finland (1) · Pakistan (1) · United Kingdom (1)
Christian M Beilstein, MD (1) · Evangelos Giamarellos-Bourboulis, MD, PhD (1) · Katerina Kotxampassi, MD, PhD (1) · Konrad E Bloch, MD (1) · Mariana Phillips, MD (1) · Saima A Professor, FCPS (1) · Sibtain Anwar, MA MB FRCA (1) · Yaling Han, Dr (1) · Yanbing Zhou (1)