26 completed, 6 withdrawn, 5 unknown, 4 terminated. 49 Phase 2, 10 Phase 1, 7 Phase 3.
Follow Photochemotherapy: new trials by email Literature Review of Photochemotherapy trials Research Report on Photochemotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 2 Study of Methylene Blue Photodynamic Therapy for Treatment of Breast Abscesses Standard of care breast abscess drainage, Methylene Blue, Lipid Emulsion - Breast Abscess | Phase 2 | Not yet recruiting | University of Rochester | 50 | 2027-07-01 | 2026-08-19 |
| Photoimmunotherapy With ASP-1929 and Cemiplimab for the Treatment of Refractory, Inoperable, and Metastatic Stage IIIB-IV Non-small Cell Lung Cancer Biospecimen Collection, Cemiplimab, Cetuximab Sarotalocan Sodium - Lung Non-Small Cell Carcinoma, Metastatic Lung Non-Small Cell Carcinoma | Phase 2 | Withdrawn | Roswell Park Cancer Institute | 2026-08-15 | 2026-09-15 | |
| PDT vs Peels for Treatment of Actinic Keratoses Photodynamic Therapy, Chemical Peels - Actinic Keratoses | Phase 2 | Not yet recruiting | Northwestern University | 60 | 2026-08-01 | 2026-07-01 |
| Photodynamic Therapy of Primary Localized Prostate Cancer With the SpectraCure P18 System Photodynamic Therapy (PDT), Verteporfin Injection - Prostate Cancer | Phase 1 / Phase 2 | Recruiting | SpectraCure AB | 43 | 2025-01-06 | 2026-05-01 |
| Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advanced or Metastatic Pancreatic Cancer Biopsy, Biospecimen Collection, Computed Tomography - Locally Advanced Pancreatic Adenocarcinoma, Metastatic Pancreatic Adenocarcinoma | Phase 2 | Active not recruiting | Mayo Clinic | 24 | 2024-12-06 | 2026-06-18 |
| Imaging Techniques to Monitor Photosensitizer and sO2 Levels During Photodynamic Therapy of Actinic Keratoses Topical Aminolevulinate, Photodynamic therapy (PDT), Red light illumination - Actinic Keratoses | Phase 2 | Completed | Case Comprehensive Cancer Center | 14 | 2024-08-25 | 2026-02-20 |
| Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer Aminolevulinic Acid, Biospecimen Collection, Computed Tomography - Locally Advanced Colorectal Carcinoma, Recurrent Colorectal Carcinoma | Phase 1 / Phase 2 | Recruiting | Roswell Park Cancer Institute | 21 | 2024-07-30 | 2026-10-15 |
| A Comparison of Photodynamic Therapy and Topical Clobetasol in Treatment of Oral Lichen Planus: a Split-Mouth Randomised Controlled Study Photodynamic Therapy, Clobetasol - Oral Lichen Planus | Phase 2 | Completed | Wroclaw Medical University | 29 | 2023-06-01 | 2024-12-30 |
| Pembrolizumab and Photodynamic Therapy in Previously Treated Metastatic Esophageal Squamous Cell Carcinoma Pembrolizumab, Sinoporphyrin Sodium, Photodynamic therapy - Esophageal Squamous Cell Carcinoma | Phase 2 | Not yet recruiting | Peking University | 54 | 2022-12-01 | 2022-11-28 |
| Safety and Efficacy of Extracorporeal Photopheresis (ECP) in the Treatment of Multiple Sclerosis Extracorporeal Photopheresis, MS standard of care - Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting | Phase 1 / Phase 2 | Completed | Abu Dhabi Stem Cells Center | 15 | 2022-03-26 | 2026-05-07 |
| Nasal Photodisinfection in All Patients Presenting for Surgery for a Wide Range of Surgical Procedures methylene blue 0.01%/chlorhexidine gluconate 0.25% + light activation - Surgical Site Infections, Nosocomial Infection | Phase 2 | Completed | Ondine Biomedical Inc. | 322 | 2022-02-04 | 2022-08-22 |
| Utilizing the Crosstalk Among Aerosolized Phenformin , Methylene Blue, Photodynamic Therapy , Zinc and Potassium for Treating Severe COVID-19 Infection and Its Inflammatory Complication Combination therapy plus Standard therapy, Photodynamic therapy, Standard therapy - COVID-19 | Phase 1 / Phase 2 | Unknown | Amr kamel khalil Ahmed | 2 | 2021-09-01 | 2021-09-24 |
| Comparison of Clinical Efficiency of Photodynamic Therapy and Topical Corticosteroid in Treatment of Oral Lichen Planus Triamcinolone Acetonide, Photodynamic Therapy - Lichen Planus, Oral | Phase 2 | Completed | Wroclaw Medical University | 30 | 2020-12-10 | 2021-08-02 |
| Antimicrobial Photodynamic Therapy in Chronic Periodontitis and Diabetes Mellitus Indocyanine green - Type 2 Diabetes Mellitus, Prediabetic State | Phase 2 / Phase 3 | Completed | King Saud University | 80 | 2020-06-01 | 2021-04-23 |
| Evaluation of the Effectiveness of Photodynamic Therapy in the Treatment of Lesions of the Lichen Planus Type in the Oral Mucosa and Its Diagnostics With the Use of Autofluorescence, in Various Wavelength Ranges, in Combination With the Use of Texture Analysis and Fractal Dimension PDT Therapy, Triamcinolone (Substance) therapy side - Oral Lichen Planus | Phase 2 | Completed | Wroclaw Medical University | 30 | 2020-02-08 | 2021-08-05 |
| Vitamin D Supplementation as a Neoadjuvant for Photodynamic Therapy of Actinic Keratoses Photodynamic therapy (PDT), Vitamin D3 - Actinic Keratosis | Phase 2 | Completed | Case Comprehensive Cancer Center | 75 | 2020-01-13 | 2022-06-24 |
| Photodynamic Therapy for the Prevention of Lung Cancer Photodynamic Therapy (PDT) - Squamous Cell Lung Cancer, Lung Cancer | Phase 2 / Phase 3 | Withdrawn | University College, London | 2018-09-01 | 2019-02-01 | |
| Photodynamic Therapy With HPPH Compared to Standard of Care Surgery in Treating Patients With Oral Cavity Cancer HPPH, Laboratory Biomarker Analysis, Photodynamic Therapy - Stage I Oral Cavity Squamous Cell Carcinoma, Stage II Oral Cavity Squamous Cell Carcinoma | Phase 2 | Terminated | Roswell Park Cancer Institute | 2 | 2018-03-07 | 2022-06-02 |
| Ultrasound-Guided Verteporfin Photodynamic Therapy for the Treatment of Unresectable Solid Pancreatic Tumors or Advanced Pancreatic Cancer, VERTPAC-02 Study Endoscopic Ultrasound, Fluorescence Imaging, Photodynamic Therapy - Advanced Pancreatic Carcinoma, Locally Advanced Pancreatic Carcinoma | Phase 2 | Completed | Mayo Clinic | 13 | 2017-05-31 | 2025-07-30 |
| Low-cost Enabling Technology for Image-guided Photodynamic Therapy (PDT) of Oral Cancer Cancer. Photodynamic Therapy - Oral Cancer | Phase 1 / Phase 2 | Completed | Massachusetts General Hospital | 30 | 2017-03-10 | 2021-02-21 |
Showing 20 of 49. Sign in to see all of them.
Keratosis, Actinic (6) · Macular Degeneration (4) · Squamous Cell Carcinoma of Head and Neck (4) · Cholangiocarcinoma (3) · Colorectal Neoplasms (3) · Lichen Planus, Oral (3) · Liver Neoplasms (3) · Barrett Esophagus (2) · Lung Neoplasms (2) · Neoplasm Metastasis (2) · Pancreatic Neoplasms (2) · Acne Vulgaris (1) · Adenocarcinoma (1) · Bile Duct Diseases (1) · Bile Duct Neoplasms (1)
Roswell Park Cancer Institute (5) · Mayo Clinic (4) · Wroclaw Medical University (3) · Case Comprehensive Cancer Center (2) · DUSA Pharmaceuticals, Inc. (2) · Light Sciences LLC (2) · QLT Inc. (2) · Abramson Cancer Center at Penn Medicine (1) · Abu Dhabi Stem Cells Center (1) · Amr kamel khalil Ahmed (1) · Asan Medical Center (1) · Asociación para Evitar la Ceguera en México (1) · Donald Basel (1) · Edward Nelson (1) · Guangzhou Medical University (1)
United States (28) · China (3) · Germany (3) · Poland (3) · Canada (2) · Saudi Arabia (2) · Chile (1) · France (1) · Hong Kong (1) · India (1) · Israel (1) · Mexico (1) · Singapore (1) · South Korea (1) · Switzerland (1)
Hassan Arshad (2) · Stuart Marcus, MD, PhD (2) · Allen Ho, MD (1) · Amr Ahmed (1) · Andrew Strong, Ph.D (1) · Anthony S Dakwar (1) · Ariel Hasson, MD (1) · Arnaud Scherpereel, MD, PhD (1) · Claes D Enk, MD, PhD (1) · Do Hyun Park, Md, PhD (1) · Donald G Basel, MD (1) · Edward L Nelson, MD (1) · Edward Maytin, MD, PhD (1) · Edward V Maytin, MD, PhD (1)
PMID 19878113, PMID 20510306, PMID 23055220, PMID 27594672, PMID 33647286, PMID 34087466, PMID 34261044, PMID 35314199, PMID 35367616, PMID 39838651
P30CA016056 (3), P01CA084203 (2), 2015 (1), 5UH3CA189901-04 (1), P01CA055791 (1), R01CA111603 (1), R21CA153594 (1), R44CA250727 (1), UL1TR001412 (1)