Oxygen: Clinical Trials

30 trials of Oxygen, newest first

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30 completed. 30 Phase 4.

By phase and status

PhaseTrialsStatus
Phase 430Completed 30

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Trials (filtered) newest first · largest first

All 30 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Effects of Different Inhalation Oxygen Concentrations on Postoperative Atelectasis
30% Oxygen, 60% Oxygen - Atelectasis
Phase 4CompletedChina Medical University, China962023-01-112024-07-22
A Pilot Study to Assess Effects of Self-Administered Nitrous Oxide (SANO) on Urodynamic Study (UDS) Parameters
Self-Administered Nitrous Oxide, Oxygen - Lower Urinary Tract Symptoms
Phase 4CompletedBeth Israel Deaconess Medical Center192023-01-102026-03-12
Intranasal Versus Intravenous Dexmedetomidine for Hypotensive Anesthesia in FESS
Intranasal dexmedetomidine, Intravenous dexmedetomidine - Functional Endoscopic Sinus Surgery, Premedication
Phase 4CompletedAl-Azhar University602022-11-102023-03-14
Oxygen Reserve Index and Prevention of Hyperoxemia
Oxygen, Masimo Root Radical 7 - Hyperoxemia, Oxygen Reserve Index
Phase 4CompletedBaskent University Ankara Hospital1082022-08-172023-05-22
Self-Administered Nitrous Oxide (SANO) During Transrectal Prostate Biopsy to Reduce Patient Anxiety and Pain
Self-Administered Nitrous Oxide, Oxygen - Prostate Disease, Malignancy
Phase 4CompletedBeth Israel Deaconess Medical Center1432021-12-122024-01-30
Sustained Mood Improvement With Laughing Gas Exposure: A Randomized Controlled Pilot Trial
Nitrous Oxide 99 %, Oxygen + Midazolam - Treatment Resistant Depression, Major Depressive Disorder
Phase 4CompletedUnity Health Toronto402021-11-032024-05-08
Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements
Non-rebreather mask (NRBM), Non-invasive ventilator mask (NIV), Nasal cannula EtO2 sensor - Rapid Sequence Intubation
Phase 4CompletedEmory University1052019-09-242025-06-13
VitamIn and oXygen Interventions and Cardiovascular Events
Oxygen, Antioxidants - Postoperative Cardiac Complication
Phase 4CompletedUniversity Hospital Bispebjerg and Frederiksberg6002018-04-062021-04-30
Neuroimaging During Pure Oxygen Breathing
Oxygen - Hyperoxia, Hypoxia, Brain
Phase 4CompletedCase Western Reserve University332017-10-022019-11-13
Handling Oxygenation Targets in the Intensive Care Unit
Oxygen - Hypoxemic Respiratory Failure, Oxygen Toxicity
Phase 4CompletedAalborg University Hospital29282017-06-192021-10-26
Pediatric Emergency Suture Care: a Trial Comparing the Analgesic Efficacy of Hypnosis Versus MEOPA
Use of MEOPA during suturing, Use of Hypnosis during suturing, Stitch removal - Wounds, Nonpenetrating
Phase 4CompletedCentre Hospitalier Universitaire de Nīmes602016-10-252025-11-17
Trial of Hyperoxic O2 Therapy vs. Normoxic O2 Therapy in Sepsis
Oxygen - Sepsis
Phase 4CompletedUniversity Hospital Plymouth NHS Trust502015-10-012017-09-19
Benefits of Liquid Oxygen in COPD Patients Presenting Desaturation During Exercise.
oxygen - Pulmonary Disease, Chronic Obstructive
Phase 4CompletedJtarrega1122015-09-012018-08-07
Optimal Oxygenation in the Intensive Care Unit
Oxygen - Systemic Inflammatory Response Syndrome
Phase 4CompletedAmsterdam UMC, location VUmc4002015-02-012021-04-19
Impact of 50% Nitrous Oxide Inhalation on Pain and Anxiety Induced by Lumbar Puncture: a Double-blind Randomized Controlled Trial
50:50 mixture of nitrous oxide/oxygen - Lumbar Puncture
Phase 4CompletedUniversity Hospital, Clermont-Ferrand662014-07-082026-11-09
Patients With Chronic Obstructive Pulmonary Disease at Altitude - Effect of Nocturnal Oxygen on Breathing and Sleep
Oxygen, sham oxygen (room air) - Chronic Obstructive Pulmonary Disease (COPD)
Phase 4CompletedUniversity of Zurich322014-06-012019-01-29
Patients With Chronic Obstructive Pulmonary Disease at Altitude - Effect of Nocturnal Oxygen on Exercise Performance
oxygen, sham oxygen (room air) - Chronic Obstructive Pulmonary Disease (COPD)
Phase 4CompletedUniversity of Zurich322014-05-012019-05-14
Patients With Pulmonary Hypertension or Interstitial Lung Disease at Altitude - Effect of Oxygen on Exercise Performance
Moderate altitude sojourn, Low altitude sojourn, Oxygen - Precapillary Pulmonary Hypertension, Interstitial Lung Disease
Phase 4CompletedUniversity of Zurich302014-05-012021-10-07
MEOPA Versus Local Anesthesia for Analgesia During Chorionic Villus Sampling.
Oxygen/nitrous oxide equimolar mix, Lidocaine - Pain
Phase 4CompletedHospital St. Joseph, Marseille, France1922013-03-132018-01-05
Ambulatory Oxygen Effects on Muscles in COPD
Oxygen, Medical air equivalent - COPD
Phase 4CompletedUniversity of Birmingham252012-08-012014-12-03

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Conditions studied

Hyperoxia (6)  ·  Pulmonary Disease, Chronic Obstructive (4)  ·  Hypoxia (3)  ·  Pain (3)  ·  Anxiety Disorders (2)  ·  Bronchitis (2)  ·  Emphysema (2)  ·  Neoplasms (2)  ·  Respiratory Insufficiency (2)  ·  Acute Pain (1)  ·  Agnosia (1)  ·  Critical Illness (1)  ·  Depressive Disorder, Major (1)  ·  Depressive Disorder, Treatment-Resistant (1)  ·  Emergencies (1)

Sponsors

University of Zurich (3)  ·  Beth Israel Deaconess Medical Center (2)  ·  Aalborg University Hospital (1)  ·  Air Liquide Santé International (1)  ·  Al-Azhar University (1)  ·  Amsterdam UMC, location VUmc (1)  ·  Baskent University Ankara Hospital (1)  ·  Case Western Reserve University (1)  ·  Centre Hospitalier Universitaire de Nīmes (1)  ·  China Medical University, China (1)  ·  Copenhagen University Hospital, Rigshospitalet (1)  ·  Emory University (1)  ·  Federal University of Minas Gerais (1)  ·  Francisco Groppo (1)  ·  Hospital St. Joseph, Marseille, France (1)

Countries

France (5)  ·  United States (5)  ·  Switzerland (4)  ·  Denmark (3)  ·  United Kingdom (3)  ·  Netherlands (2)  ·  Austria (1)  ·  Brazil (1)  ·  Canada (1)  ·  China (1)  ·  Egypt (1)  ·  Finland (1)  ·  Iceland (1)  ·  Italy (1)  ·  Norway (1)

Top investigators

Konrad E Bloch, MD (3)  ·  Heidi Rayala, MD, PhD (2)  ·  Alice M Turner (1)  ·  Anders Perner, MD, PhD (1)  ·  Bodil Steen Rasmussen, MD, PhD (1)  ·  Christian S Meyhoff, MD (1)  ·  Christian S. Meyhoff, MD, PhD (1)  ·  Lars S Rasmussen, MD, PHD, DMSC (1)

Results publications

PMID 19826023, PMID 21511500, PMID 22840231, PMID 23406077, PMID 23406914, PMID 25015353, PMID 27666149, PMID 29436868, PMID 32070283, PMID 32568400, PMID 32659856, PMID 33471452, PMID 34305642, PMID 34425016, PMID 34463696, PMID 34645842, PMID 34674834, PMID 35441849, PMID 37196799, PMID 37588787, PMID 37700687, PMID 38241247, PMID 38711834, PMID 38990335, PMID 40920961, PMID 41055553

NIH funding

2014 (3), 2015 (1), 2017 (1)