12 completed, 3 unknown, 2 recruiting, 1 active not recruiting. 6 Phase 4, 5 Not applicable, 4 Phase 2, 3 Phase 3, 2 Early Phase 1.
Follow Ortho Evra: new trials by email Literature Review of Ortho Evra trials Research Report on Ortho Evra
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cyclic vs. Constant Estradiol: Regimens' Effects on Brain Health Cyclic Estradiol, Continuous Estradiol - Menopause, Healthy Adult | Phase 4 | Recruiting | University of Colorado, Denver | 40 | 2026-07-15 | 2026-09-21 |
| Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite Athletes Testosterone Enanthate, Testosterone Cypionate, Testosterone Propionate - Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite Athletes | Not applicable | Enrolling by invitation | Enhanced Emirates Limited | 60 | 2026-03-12 | 2026-05-06 |
| Role of Menopause in Thermoregulation Elagolix Oral Tablet, Estradiol patch, cellulose placebo - Menopause, Aging | Phase 4 | Recruiting | Penn State University | 24 | 2025-03-01 | 2026-10-02 |
| Rhythmic Estradiol and Bone Health Estradiol patch, Progesterone - Osteoporosis Risk, Menopause | Phase 4 | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 48 | 2023-07-19 | 2026-10-16 |
| Androgen Blockade and Progesterone Augmentation of Gonadotropin Secretion Micronized progesterone, Placebo, Flutamide - PCOS, Polycystic Ovary Syndrome | Early Phase 1 | Unknown | University of Virginia | 10 | 2022-10-26 | 2023-11-02 |
| Estrogen Administration for the Treatment of NASH in Postmenopausal Women Estradiol patch, Placebo - NASH - Nonalcoholic Steatohepatitis | Phase 3 | Active not recruiting | Massachusetts General Hospital | 50 | 2021-12-02 | 2026-08-07 |
| Estrogen Patch for COVID-19 Symptoms Estradiol patch - COVID | Phase 2 | Terminated | Sharon Nachman | 2 | 2020-04-20 | 2021-11-26 |
| Neuroendocrine Risk for PTSD in Women Estradiol patch, Placebo patch - PTSD, Trauma | Early Phase 1 | Completed | Emory University | 127 | 2019-11-11 | 2026-07-22 |
| The Interaction Between Diabetes and Estradiol on Human Brain Metabolism in Postmenopausal Women Estradiol patch - Diabetes Type 2, Dementia | Phase 1 | Completed | Wake Forest University Health Sciences | 12 | 2019-05-13 | 2022-09-27 |
| Oophorectomy, Estrogen Therapy and Cardiovascular Disease Risk in Young Women Estradiol 100 Micrograms Patch, Estradiol Patch - Cardiovascular Risk Reduction | Phase 2 | Completed | Mayo Clinic | 35 | 2019-03-15 | 2024-10-23 |
| Primary Ovarian Insufficiency: Phenotype and Optimal Treatment Transdermal Estrogen - Primary Ovarian Insufficiency | Phase 3 | Completed | Children's Hospital Medical Center, Cincinnati | 19 | 2018-11-01 | 2024-06-25 |
| Sex Differences in Myocardial Steatosis Induced Left Ventricular Dysfunction Estradiol patch, Cetrotide, Fasting - Heart Diseases, Left Ventricular Dysfunction | Phase 4 | Unknown | The University of Texas at Arlington | 100 | 2018-09-13 | 2024-02-20 |
| Effects of Oral vs. Non-oral Contraceptives on the GH/IGF-1 Axis Combined Oral Contraceptive, Transdermal Contraceptive, Contraceptive Vaginal Ring - Bone; Disorder, Development and Growth | Phase 4 | Completed | Penn State University | 60 | 2015-01-01 | 2020-03-09 |
| Birth Control Patch Study Ethinylestradiol/Gestodene (FC Patch Low BAY86-5016), Norelgestromin/Ethinylestradiol (EVRA) - Contraception | Phase 3 | Completed | Bayer | 393 | 2009-05-01 | 2014-04-02 |
| The Effect of Hormonal Contraceptives on Androgens and Glucose Metabolism Desogestrel-Ethinyl Estradiol contraceptive pill, Etonogestrel-Ethinyl Estradiol vaginal ring, Norelgestromin-Ethinyl Estradiol contraceptive patch - Contraception | Not applicable | Completed | University of Oulu | 45 | 2007-10-01 | 2011-09-07 |
| Oral Versus Patch Hormonal Contraceptive Effects on Metabolism, Clotting, Inflammatory Factors and Vascular Reactivity Ortho-Cyclen (R), Ortho Evra (R), extended use of Ortho Evra (R) - Contraception | Phase 2 | Unknown | University of Washington | 36 | 2007-02-01 | 2011-02-14 |
| KEEPS Mammographic Density And Breast Health Ancillary Study CEE pill, Estradiol patch, Active Progesterone - Mammographic Density, Abnormal Mammogram | Not applicable | Completed | Brigham and Women's Hospital | 517 | 2005-09-01 | 2017-03-08 |
| A Trial in Healthy Female Subjects to Compare the Pharmacokinetics of Ethinyl Estradiol of NuvaRing®, a Contraceptive Patch (EVRA(TM)) and an Oral Contraceptive (Microgynon® 30) (Study 34237 (P06650)) (COMPLETED) Levonorgestrel (LNG)/Ethinylestradiol (EE) oral contraceptive tablets, norelgestrominum and ethinylestradiol patch oral contraceptive patch, Nuvaring ™ (etonorgestrel/ethinylestradiol) - Contraception | Phase 4 | Completed | Organon and Co | 24 | 2004-03-01 | 2022-02-04 |
| Birth Control Pill vs Birth Control Patch Study Ethinyl estradiol and norgestimate, Ethinyl estradiol and norelgestromin - Venous Thrombosis | Not applicable | Completed | University of Vermont | 24 | 2003-04-01 | 2007-11-07 |
| Drug Interactions Between Lopinavir/Ritonavir and Oral or Patch Contraceptives in HIV Infected Women Lopinavir/ritonavir, Ortho Novum 1/35, Ortho Evra - HIV Infections, Pregnancy | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 32 | 2021-11-01 |
Showing 20 of 21. Sign in to see all of them.
Cardiovascular Diseases (1) · Dementia (1) · Diabetes Mellitus, Type 2 (1) · Dysmenorrhea (1) · Fasting (1) · HIV Infections (1) · Heart Diseases (1) · Heat Stress Disorders (1) · Hemorrhage (1) · Inflammation (1) · Insulin Resistance (1) · Menstruation Disturbances (1) · Non-alcoholic Fatty Liver Disease (1) · Polycystic Ovary Syndrome (1) · Primary Ovarian Insufficiency (1)
Penn State University (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Bayer (1) · Brigham and Women's Hospital (1) · Children's Hospital Medical Center, Cincinnati (1) · Emory University (1) · Enhanced Emirates Limited (1) · Massachusetts General Hospital (1) · Mayo Clinic (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Organon and Co (1) · Sharon Nachman (1) · The University of Texas at Arlington (1) · University of California, San Francisco (1) · University of Colorado, Denver (1)
United States (14) · Netherlands (2) · Austria (1) · Czechia (1) · Finland (1) · Puerto Rico (1) · United Arab Emirates (1)
Catherine Gordon, MD,Msc (1) · Christina Hugenschmidt, PhD (1) · Christopher M McCartney, MD (1) · Ekta Kapoor, MBBS (1) · Eleanor Drey, MD, EdM (1) · Halley Wasserman, MD, MSc (1) · Jennifer Stevens, PhD (1) · Johanna M. Puurunen, MD (1) · Juha S. Tapanainen, Professor (1) · Julia V Johnson, MD (1) · Karen K. Miller, MD (1) · Kathy Rexrode, MD (1) · Lori Kamemoto, MD, MPH (1) · Mary Jane De Souza, PhD (1)
PMID 16102549, PMID 18238963, PMID 20842042, PMID 21917867, PMID 22811306, PMID 23260855, PMID 25453582, PMID 32612574, PMID 33240091
2008 (1), R01CA136918 (1), R01DK126955 (1), R01HD102060 (1), R01MH117009 (1), R21AG054955 (1)