30 completed, 5 active not recruiting, 2 not yet recruiting, 2 recruiting. 17 Not applicable, 12 Phase 4, 5 Phase 1, 5 Phase 2, 4 Phase 3.
Follow this drug Literature Review of Nicotine Lozenge trials Research Report on Nicotine Lozenge
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| iCanQuit Smoking Cessation Among Hispanic Adults iCanQuit Smartphone App Smoking Cessation Program, Nicotine Gum, Nicotine Patch - Cigarette Smoking-Related Carcinoma | Phase 3 | Not yet recruiting | Fred Hutchinson Cancer Center | 854 | 2026-10-15 | 2026-09-21 |
| Evaluation of Dependence and Nicotine Replacement Therapy-Supported Cessation Efforts Among Regular Electronic Cigarette Use Nicotine Replacement Therapies, Brief Behavioral Counseling - E Cigarette Use, Cessation, Tobacco | Phase 4 | Not yet recruiting | West Virginia University | 100 | 2026-09-01 | 2026-08-26 |
| Oral Nicotine Pouches Versus Nicotine Replacement Therapy to Reduce Cigarette Use for Smokers in Rural Appalachia Carbon Monoxide Measurement, Nicotine Lozenge, Oral Nicotine Pouch - Cigarette Smoking-Related Carcinoma | Not applicable | Recruiting | Ohio State University Comprehensive Cancer Center | 1000 | 2025-06-13 | 2026-06-30 |
| Feasibility of Delivering VergeRx at FQHCs QuitAid, SmokefreeTXT, Nicotine Replacement Therapy Patch - Tobacco Use Cessation | Not applicable | Active not recruiting | University of Virginia | 100 | 2024-09-23 | 2025-10-30 |
| Adaptive Use of Nicotine Substitution to Maintain Smoking Reduction/Abstinence in Nicotine Responders Nicoderm, Nicorette 4Mg Chewing Gum, Nicorette Lozenge Product - Smoking Cessation, Harm Reduction | Phase 3 | Completed | Rose Research Center, LLC | 150 | 2024-08-29 | 2026-02-06 |
| Evaluate Harm Reduction Products as a Second Line Intervention for Adult Smokers Who Do Not Quit With NRT Nicoderm, Nicorette 4Mg Chewing Gum, Nicorette Lozenge Product - Smoking Cessation, Harm Reduction | Phase 3 | Terminated | Rose Research Center, LLC | 4 | 2023-12-27 | 2025-03-30 |
| Free Samples for Health Ask-Advise-Refer, Nicotine Patch, 14 Mg/24 Hr Transdermal Film, Extended Release, Nicotine lozenge - Cigarette Smoking | Phase 2 | Completed | Sandra Japuntich | 1239 | 2023-06-12 | 2026-07-24 |
| Integrating Tobacco Use Cessation Into HIV Care and Treatment in Kisumu County, Kenya Tobacco Use Cessation Counselling Sessions, Bupropion, Nicotine patch - Tobacco Use Cessation, Tobacco Use | Phase 4 | Completed | University of California, San Francisco | 580 | 2023-05-16 | 2025-07-02 |
| Smoking Cessation and Menstrual Cycle Phase Timing of nicotine replacement therapy start date, Nicotine Replacement Therapy Agent - Nicotine Dependence, Tobacco Smoking | Phase 4 | Recruiting | Centre for Addiction and Mental Health | 1200 | 2022-11-30 | 2026-03-19 |
| Enhancing Long-Term Smoking Abstinence Among Cervical Cancer Survivors (Project ACCESS) Smoking Cessation treatment delivered by Tobacco Free Florida Quitline, Nicotine patch, Nicotine Lozenge - Smoking Cessation, Cervical Cancer | Not applicable | Active not recruiting | H. Lee Moffitt Cancer Center and Research Institute | 360 | 2022-11-29 | 2026-04-01 |
| Easy Access to Smoking Cessation for People Receiving Opioid Agonist Therapy Who Are Smoking Tobacco Nicotine patch, Nicotine gum, Nicotine lozenge - Smoking Cessation, Substance-Related Disorders | Not applicable | Active not recruiting | Haukeland University Hospital | 266 | 2022-04-07 | 2024-06-28 |
| Methadone-Maintained Smokers Switching to E-Cigarettes Electronic Cigarette, Nicotine Lozenge - Nicotine Dependence, Electronic Cigarette Use | Phase 4 | Completed | Butler Hospital | 183 | 2022-03-31 | 2026-08-20 |
| Automated Video-Assisted Smoking Treatment for People Living With HIV Nicotine patch, Counseling, Nicotine lozenge - Smoking Cessation | Not applicable | Active not recruiting | H. Lee Moffitt Cancer Center and Research Institute | 512 | 2021-12-15 | 2026-09-25 |
| Partnering With Food Bank to Provide Tobacco Treatment to Underserved Smokers Smartphone-delivered automated treatment, Nicotine patch, Counseling - Smoking Cessation | Not applicable | Completed | H. Lee Moffitt Cancer Center and Research Institute | 502 | 2021-12-01 | 2026-09-24 |
| Research and Innovation to Stop E-cigarette/Vaping in Young Adults Nicotine patch, Phone Counseling, Digital Coaching - Nicotine Dependence, E-Cig Use | Phase 4 | Completed | Ohio State University | 508 | 2021-07-28 | 2024-07-29 |
| Inpatient Smoking Cessation Pilot Program Nicotine lozenge, Nicotine gum, Nicotine patch - Tobacco Use Cessation | Early Phase 1 | Withdrawn | Johns Hopkins University | 2019-10-01 | 2023-08-15 | |
| Comparing NicoBloc to Nicotine Lozenges NicoBloc, Nicotine Lozenge - Smoking Cessation, Nicotine Dependence | Phase 2 / Phase 3 | Completed | University of Alabama at Birmingham | 45 | 2019-03-21 | 2025-04-08 |
| Treating Smokers With Mental Illness Nicotine patch, Nicotine lozenge, Therapy - Smoking Cessation, Cigarette Smoking | Phase 2 | Completed | University of Minnesota | 38 | 2019-03-01 | 2021-05-25 |
| Single-Dose Bioequivalence Study Comparing Two 2 mg Nicotine Lozenges Nicotine lozenge - Smoking Cessation | Phase 1 | Completed | Fertin Pharma A/S | 42 | 2018-02-19 | 2018-08-09 |
| Single-Dose Bioequivalence Study Comparing Two 4 mg Nicotine Lozenges Nicotine lozenge - Smoking Cessation | Phase 1 | Completed | Fertin Pharma A/S | 42 | 2018-01-15 | 2018-08-09 |
Showing 20 of 43. Sign in to see all of them.
Smoking Cessation (19) · Tobacco Use Disorder (16) · Smoking (9) · Tobacco Use Cessation (5) · Tobacco Use (4) · Cigarette Smoking (3) · Harm Reduction (3) · Uterine Cervical Neoplasms (3) · Vaping (3) · Substance-Related Disorders (2) · Bipolar Disorder (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Renal Cell (1) · Depression (1)
Duke University (5) · H. Lee Moffitt Cancer Center and Research Institute (4) · University of Minnesota (3) · University of Wisconsin, Madison (3) · Centre for Addiction and Mental Health (2) · Fertin Pharma A/S (2) · National Institute on Drug Abuse (NIDA) (2) · Rose Research Center, LLC (2) · Butler Hospital (1) · Fox Chase Cancer Center (1) · Fred Hutchinson Cancer Center (1) · Haukeland University Hospital (1) · Johns Hopkins University (1) · M.D. Anderson Cancer Center (1) · Mark Vander Weg (1)
United States (35) · Canada (2) · South Africa (2) · Kenya (1) · Norway (1) · Sweden (1)
Damon J Vidrine, Dr.PH (2) · Yolandi Swart, Dr. (2) · Amy Janes, Ph.D (1) · Brittney L Keller-Hamilton, PhD, MPH (1) · David O Warner, MD (1) · Dorohty Hatsukami, Ph.D. (1) · Dorothy Hatsukami, PhD (1) · Elisabeth Kruse, PhD (1) · Elizabeth G Klein, PhD (1) · Eric E Soule, Ph.D (1) · Harry Lando, PhD (1) · James H Stein, MD (1) · Jamie Ostroff, PhD (1) · Jason Robinson (1) · Jean C Beckham, Ph.D. (1)
PMID 37142273, PMID 39868569, PMID 20008701, PMID 20078491, PMID 20236788, PMID 21885891, PMID 22123796, PMID 22172440, PMID 22496918, PMID 22608375, PMID 24893290, PMID 24938369, PMID 25192771, PMID 25699616, PMID 25867447, PMID 26813210, PMID 28235705, PMID 29251951, PMID 31056710, PMID 31422759, PMID 32800078, PMID 33593332, PMID 34198131, PMID 34347865, PMID 34787590, PMID 35317789, PMID 35474254, PMID 35978334, PMID 35978355, PMID 37005655, PMID 37230961, PMID 37335995, PMID 37403057, PMID 37579108, PMID 38184633, PMID 38696203, PMID 39198824, PMID 39665734, PMID 39937506, PMID 41433314
P50DA019706 (2), 2008 (1), K01DA029645 (1), R00DA037276 (1), R01CA172786 (1), R01CA231952 (1), R01CA243552 (1), R01CA289551 (1), R01CA298383 (1), R01DA021619 (1), R01DA052907 (1), R01HL109031 (1), R15DA059750 (1), R21DA029689 (1), R34DA030652 (1)