26 completed. 26 Phase 2, 8 Phase 1, 4 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 26 | Completed 26 |
| Phase 1 | 8 | Completed 8 |
| Phase 3 | 4 | Completed 4 |
Follow Furosemide: new trials by email Literature Review of Furosemide trials Research Report on Furosemide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Ultra High Dose Diuretics to Treat Heart Failure Bumetanide, Furosemide - Heart Failure; With Decompensation | Phase 2 | Completed | Mayo Clinic | 20 | 2023-11-27 | 2026-01-14 |
| Acute Effects of Furosemide on Hemodynamics and Pulmonary Congestion in Acute Decompensated Heart Failure. Furosemide Injection - Acute Heart Failure | Phase 1 / Phase 2 | Completed | Johannes Grand | 20 | 2023-09-01 | 2024-02-16 |
| Low Dose Continuous Furosemide Effect on Cardiac Surgery Patients With Kidney Dysfunction Furosemide in 0.9 % NaCl 100 Mg/100 mL (1 mg/mL), NaCl 0.9% - Chronic Kidney Disease, Cardiac Disease | Phase 2 | Completed | National Cardiovascular Center Harapan Kita Hospital Indonesia | 90 | 2021-05-27 | 2024-01-05 |
| Crossover Study to Compare the Pharmacokinetics and Bioavailability of a Novel Furosemide Regimen Administered Subcutaneously vs. the Same Dose Administered Intravenously in Subjects With Chronic Heart Failure Furosemide Injection Solution for subcutaneous administration (80 mg), Furosemide Injection, USP, Medfusion 3500 (v6) precision infusion pump - Heart Failure | Phase 1 / Phase 2 | Completed | SQ Innovation, Inc. | 20 | 2020-10-17 | 2026-06-15 |
| Pilot Study of Loop Diuretics Among Individuals Receiving Hemodialysis Furosemide (loop diuretic) Tablets - Chronic Kidney Disease Requiring Chronic Dialysis | Phase 2 | Completed | University of North Carolina, Chapel Hill | 39 | 2020-10-07 | 2022-06-13 |
| A Trial to Study BAY1753011 in Patients With Congestive Heart Failure BAY 1753011, Placebo BAY 1753011, Furosemide - Heart Failure (HF) | Phase 2 | Completed | Bayer | 482 | 2019-05-29 | 2022-04-18 |
| An Investigational Study of Continuous 8-Hour Intravenous Administrations of BMS-986231 in Participants With Heart Failure and Reduced Heart Function Given a Standard Dose of Loop Diuretic BMS-986231, Furosemide, Placebo - Cardiac Failure, Myocardial Failure | Phase 2 | Completed | Bristol-Myers Squibb | 23 | 2019-01-17 | 2021-02-26 |
| Furosemide for Accelerated Recovery of Blood Pressure Postpartum Oral furosemide, Placebo Oral Tablet - Hypertension, Pregnancy-Induced | Phase 2 | Completed | University of Pennsylvania | 384 | 2018-06-20 | 2020-09-10 |
| Effects of Adding Hypertonic Saline Solutions and/or Etilefrine to Standard Diuretics Therapy in Hepatic Ascites Oral standard diuretics therapy, Hypertonic saline solution, Etilefrine - Hepatic Ascites | Phase 2 | Completed | Hala Abd EL-Tawab Ibrahim Radwan | 90 | 2017-11-30 | 2021-03-08 |
| Furosemide and Coarctation Surgery Lung Complications Furosemide - Pulmonary Complication | Phase 2 | Completed | Cairo University | 56 | 2017-11-22 | 2017-12-27 |
| Sub-Q Versus IV Furosemide in Acute Heart Failure Furosemide Injection Solution (SCP-101), Furosemide Injection Solution, USP - Congestive Heart Failure | Phase 2 / Phase 3 | Completed | Johns Hopkins University | 40 | 2016-02-01 | 2017-12-18 |
| Safety of Furosemide in Premature Infants at Risk of Bronchopulmonary Dysplasia (BPD) Furosemide Cohort 1, Furosemide Cohort 2, Furosemide Cohort 3 - Bronchopulmonary Dysplasia | Phase 2 | Completed | University of North Carolina, Chapel Hill | 82 | 2015-11-27 | 2021-12-28 |
| Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation Rituximab, Conditioning chemotherapy, TMS - Myelodysplastic Syndromes, Hodgkin's Lymphoma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 34 | 2015-09-24 | 2025-09-30 |
| Crossover Study to Compare the Pharmacokinetics and Bioavailability of a Novel Furosemide Regimen Administered Subcutaneously vs. the Same Dose Administered Intravenously in Subjects With Chronic Heart Failure Fursemide Injection Solution for subcutaneous administration (80 mg), Furosemide Injection, USP - Heart Failure | Phase 2 / Phase 3 | Completed | scPharmaceuticals, Inc. | 23 | 2015-04-01 | 2022-12-02 |
| A Phase 2 Efficacy Study of CLS003 ICVT in Subjects With Cutaneous Warts. CLS003, Furosemide, Digoxin - Cutaneous Warts | Phase 2 | Completed | Maruho Co., Ltd. | 81 | 2015-01-01 | 2016-07-28 |
| Furosemide Pharmacodynamics and Pharmacokinetics After Subcutaneous or Oral Administration Furosemide injection solution for subcutaneous administration (80 mg), Oral Furosemide tablets (80 mg) - Heart Failure | Phase 1 / Phase 2 | Completed | scPharmaceuticals, Inc. | 10 | 2014-12-01 | 2018-06-27 |
| Aerosol Inhalation Treatment for Dyspnea - Patients Furosemide, Aerosolized saline - Dyspnea | Phase 1 / Phase 2 | Completed | Beth Israel Deaconess Medical Center | 24 | 2014-11-01 | 2018-01-23 |
| Single Dose of Furosemide to Improve Respiratory Distress in Moderate to Severe Bronchiolitis Furosemide, Placebo - Bronchiolitis | Phase 2 | Completed | Northwell Health | 46 | 2013-10-01 | 2016-08-12 |
| Role of Midodrine and Tolvaptan in Patients With Cirrhosis With Refractory or Recurrent Ascites Standard medical therapy, Tolvaptan, Midodrine - Cirrhosis, Refractory/Recurrent Ascites | Phase 2 / Phase 3 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 50 | 2013-07-01 | 2017-09-19 |
| Lintuzumab-Ac225 in Older Acute Myeloid Leukemia (AML) Patients Cytarabine (Phase 1 only), Lintuzumab-Ac225, Furosemide (Phase 1 only) - AML | Phase 1 / Phase 2 | Completed | Actinium Pharmaceuticals | 40 | 2012-10-01 | 2023-07-20 |
Showing 20 of 26. Sign in to see all of them.
Heart Failure (10) · Ascites (2) · Dyspnea (2) · Acute Lung Injury (1) · Bronchiolitis (1) · Bronchopulmonary Dysplasia (1) · Fibrosis (1) · Heart Diseases (1) · Hodgkin Disease (1) · Hypertension (1) · Hypertension, Pregnancy-Induced (1) · Kidney Failure, Chronic (1) · Leukemia (1) · Lung Diseases (1) · Lymphoma (1)
Beth Israel Deaconess Medical Center (2) · Mayo Clinic (2) · University of North Carolina, Chapel Hill (2) · scPharmaceuticals, Inc. (2) · Actinium Pharmaceuticals (1) · Bayer (1) · Bristol-Myers Squibb (1) · Cairo University (1) · Hala Abd EL-Tawab Ibrahim Radwan (1) · Hebei Medical University (1) · Johannes Grand (1) · Johns Hopkins University (1) · Maruho Co., Ltd. (1) · National Cancer Institute (NCI) (1) · National Cardiovascular Center Harapan Kita Hospital Indonesia (1)
United States (14) · Egypt (2) · Germany (2) · Netherlands (2) · Austria (1) · Bulgaria (1) · China (1) · Denmark (1) · Greece (1) · Hungary (1) · India (1) · Indonesia (1) · Israel (1) · Italy (1) · Lithuania (1)
Alain Mina, M.D. (1) · Avinash Desai, MD (1) · Bambang Widyantoro, PhD (1) · Bernhard Roth, Prof. Dr. (1) · Bruce G Rankin, DO, CPI, FACOFP (1) · Bruce G. Rankin, DO, CPI, MRO, FACOFP (1) · Charles Phillips, M.D. (1) · Gamal A Badra, professor (1) · Horng H Chen, MD (1) · Jason E Lang, MD, MPH (1) · Jennifer Flythe, MD, MPH (1) · Johannes Grand (1) · Kunshen Liu, MD (1)
PMID 11232182, PMID 12660656, PMID 15196097, PMID 16474108, PMID 17172977, PMID 19602136, PMID 20346637, PMID 21749847, PMID 22844565, PMID 24462960, PMID 24811138, PMID 24829672, PMID 25262369, PMID 26630543, PMID 27614145, PMID 27941973, PMID 27991854, PMID 28285098, PMID 28661458, PMID 28932357, PMID 29174754, PMID 29226816, PMID 29608812, PMID 30580460, PMID 30992841, PMID 31168885, PMID 33188886, PMID 33550824, PMID 3522371, PMID 35357290, PMID 37102974, PMID 37804170, PMID 38903022, PMID 40306549, PMID 40331908, PMID 40788619, PMID 41773006, PMID 42489380, PMID 680588
2018 (2), R01NR012009 (2), 2014 (1), P01HL076611 (1), R01HL084155 (1), R03DK124651 (1), UL1TR000135 (1)