26 completed, 3 terminated, 3 unknown, 3 withdrawn. 38 Phase 2, 9 Phase 1, 8 Phase 3.
Follow Furosemide: new trials by email Literature Review of Furosemide trials Research Report on Furosemide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Furosemide vs Placebo in Severe Preeclampsia Postpartum Furosemide, Folic Acid 5 MG - Severe Preeclampsia | Phase 2 | Not yet recruiting | Universidad Nacional Autonoma de Honduras | 186 | 2026-06-15 | 2026-06-15 |
| Role of Active Deresuscitation After Resuscitation: Furosemide Injection, Metolazone Tablets - Fluid Overload, Critical Illness | Phase 2 | Unknown | Unity Health Toronto | 120 | 2024-05-01 | 2024-03-22 |
| The Impact of Inhaled Furosemide and Perorally Administered Levodropropizine on Dyspnea in Patients With Respiratory Diseases Furosemide 40 mg, Levodropropizine, Placebo - saline - Dyspnea | Phase 2 / Phase 3 | Unknown | University Hospital Hradec Kralove | 102 | 2024-02-27 | 2024-04-16 |
| A Study of Ultra High Dose Diuretics to Treat Heart Failure Bumetanide, Furosemide - Heart Failure; With Decompensation | Phase 2 | Completed | Mayo Clinic | 20 | 2023-11-27 | 2026-01-14 |
| Acute Effects of Furosemide on Hemodynamics and Pulmonary Congestion in Acute Decompensated Heart Failure. Furosemide Injection - Acute Heart Failure | Phase 1 / Phase 2 | Completed | Johannes Grand | 20 | 2023-09-01 | 2024-02-16 |
| Diuretic Efficacy of Aminophylline and Furosemide Combination vs Furosemide Alone in Critically Ill Adults Aminophylline, Frusemide - Acute Kidney Injury | Phase 2 / Phase 3 | Unknown | University of Malaya | 132 | 2023-07-02 | 2023-07-11 |
| Comparison of 18F-rhPSMA-7.3 PET/CT With and Without Furosemide in Biochemical Recurrence of Prostate Cancer Furosemide, F18-rhPSMA-7.3, Positron Emission Tomography - Prostate Adenocarcinoma, Recurrent Prostate Carcinoma | Phase 2 | Active not recruiting | Emory University | 20 | 2023-04-27 | 2025-10-27 |
| Prolonged Intravenous Therapy Versus Early Initiation of an Oral Loop Diuretic in Decompensated Heart Failure Furosemide Pill 150% equivalent iv dose, Furosemide Pill 200% equivalent iv dose, Furosemide Injection - Heart Failure | Phase 2 / Phase 3 | Withdrawn | Jan Kochanowski University | 2022-12-07 | 2025-02-20 | |
| Salt-Sensitivity and Immunity Cell Activation Furosemide 40 mg - High Blood Pressure, Salt; Excess | Phase 1 / Phase 2 | Active not recruiting | Vanderbilt University Medical Center | 20 | 2021-09-01 | 2025-10-21 |
| Low Dose Continuous Furosemide Effect on Cardiac Surgery Patients With Kidney Dysfunction Furosemide in 0.9 % NaCl 100 Mg/100 mL (1 mg/mL), NaCl 0.9% - Chronic Kidney Disease, Cardiac Disease | Phase 2 | Completed | National Cardiovascular Center Harapan Kita Hospital Indonesia | 90 | 2021-05-27 | 2024-01-05 |
| Crossover Study to Compare the Pharmacokinetics and Bioavailability of a Novel Furosemide Regimen Administered Subcutaneously vs. the Same Dose Administered Intravenously in Subjects With Chronic Heart Failure Furosemide Injection Solution for subcutaneous administration (80 mg), Furosemide Injection, USP, Medfusion 3500 (v6) precision infusion pump - Heart Failure | Phase 1 / Phase 2 | Completed | SQ Innovation, Inc. | 20 | 2020-10-17 | 2026-06-15 |
| Pilot Study of Loop Diuretics Among Individuals Receiving Hemodialysis Furosemide (loop diuretic) Tablets - Chronic Kidney Disease Requiring Chronic Dialysis | Phase 2 | Completed | University of North Carolina, Chapel Hill | 39 | 2020-10-07 | 2022-06-13 |
| A Trial to Study BAY1753011 in Patients With Congestive Heart Failure BAY 1753011, Placebo BAY 1753011, Furosemide - Heart Failure (HF) | Phase 2 | Completed | Bayer | 482 | 2019-05-29 | 2022-04-18 |
| An Investigational Study of Continuous 8-Hour Intravenous Administrations of BMS-986231 in Participants With Heart Failure and Reduced Heart Function Given a Standard Dose of Loop Diuretic BMS-986231, Furosemide, Placebo - Cardiac Failure, Myocardial Failure | Phase 2 | Completed | Bristol-Myers Squibb | 23 | 2019-01-17 | 2021-02-26 |
| Furosemide for Accelerated Recovery of Blood Pressure Postpartum Oral furosemide, Placebo Oral Tablet - Hypertension, Pregnancy-Induced | Phase 2 | Completed | University of Pennsylvania | 384 | 2018-06-20 | 2020-09-10 |
| Treatment of Post-Operative Sinonasal Polyposis With Topical Furosemide Furosemide, Placebo - Nasal Polyps | Phase 2 | Terminated | Thomas Jefferson University | 18 | 2017-12-01 | 2023-08-30 |
| Effects of Adding Hypertonic Saline Solutions and/or Etilefrine to Standard Diuretics Therapy in Hepatic Ascites Oral standard diuretics therapy, Hypertonic saline solution, Etilefrine - Hepatic Ascites | Phase 2 | Completed | Hala Abd EL-Tawab Ibrahim Radwan | 90 | 2017-11-30 | 2021-03-08 |
| Furosemide and Coarctation Surgery Lung Complications Furosemide - Pulmonary Complication | Phase 2 | Completed | Cairo University | 56 | 2017-11-22 | 2017-12-27 |
| Delayed Renal Allograft Function and Furosemide Treatment Furosemide, Placebo - Delayed Graft Function | Phase 2 | Withdrawn | Loma Linda University | 2016-09-01 | 2016-11-25 | |
| Evaluation of the Efficacy of Diuretics for Symptomatic Malignant Ascites Episodes in Advanced Stage of Cancer (DIASC) Spironolactone (+/- Furosemide) - Cancer | Phase 2 | Terminated | Centre Oscar Lambret | 14 | 2016-05-30 | 2019-05-16 |
Showing 20 of 38. Sign in to see all of them.
Heart Failure (11) · Hypertension (4) · Critical Illness (3) · Dyspnea (3) · Acute Kidney Injury (2) · Ascites (2) · Hypertension, Pregnancy-Induced (2) · Pre-Eclampsia (2) · Respiratory Distress Syndrome (2) · Sepsis (2) · Acute Lung Injury (1) · Bronchiolitis (1) · Bronchopulmonary Dysplasia (1) · Delayed Graft Function (1) · Edema (1)
Beth Israel Deaconess Medical Center (2) · Mayo Clinic (2) · University of North Carolina, Chapel Hill (2) · scPharmaceuticals, Inc. (2) · Actinium Pharmaceuticals (1) · Bayer (1) · Bristol-Myers Squibb (1) · Cairo University (1) · Centre Oscar Lambret (1) · Emory University (1) · Hala Abd EL-Tawab Ibrahim Radwan (1) · Hebei Medical University (1) · Indiana University (1) · Jan Kochanowski University (1) · Johannes Grand (1)
United States (19) · Canada (2) · Egypt (2) · Germany (2) · Netherlands (2) · Poland (2) · Australia (1) · Austria (1) · Bulgaria (1) · China (1) · Czechia (1) · Denmark (1) · France (1) · Greece (1) · Honduras (1)
Alain Mina, M.D. (1) · Amir Abdipour, MD (1) · Annet Kirabo (1) · Avinash Desai, MD (1) · Bambang Widyantoro, PhD (1) · Bernhard Roth, Prof. Dr. (1) · Bruce G Rankin, DO, CPI, FACOFP (1) · Bruce G. Rankin, DO, CPI, MRO, FACOFP (1) · Charles Phillips, M.D. (1) · Charles V. Marcus, MBBS (1) · Gamal A Badra, professor (1) · Haw Shyan Ng (1) · Horng H Chen, MD (1)
PMID 11232182, PMID 12660656, PMID 15196097, PMID 16474108, PMID 17172977, PMID 19602136, PMID 20346637, PMID 20459801, PMID 21749847, PMID 22844565, PMID 24462960, PMID 24811138, PMID 24829672, PMID 25262369, PMID 26630543, PMID 27614145, PMID 27941973, PMID 27991854, PMID 28285098, PMID 28661458, PMID 28732314, PMID 28932357, PMID 29174754, PMID 29226816, PMID 29608812, PMID 30580460, PMID 30992841, PMID 31168885, PMID 33188886, PMID 33550824, PMID 3522371, PMID 35357290, PMID 37102974, PMID 37804170, PMID 38903022, PMID 39848765, PMID 39878152, PMID 40306549, PMID 40331908, PMID 40788619, PMID 41773006, PMID 42489380, PMID 680588
2018 (3), R01NR012009 (2), 2014 (1), P01HL076611 (1), P30CA138292 (1), R01HL084155 (1), R03DK124651 (1), UL1TR000135 (1)