12 completed, 4 unknown, 2 terminated, 1 active not recruiting. 8 Not applicable, 4 Phase 2, 3 Phase 1, 2 Early Phase 1, 2 Phase 3.
Follow Fatty Acids, Unsaturated: new trials by email Literature Review of Fatty Acids, Unsaturated trials Research Report on Fatty Acids, Unsaturated
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effectiveness of Omega-3 Poly Unsaturated Fatty Acids on The Treatment of Gingival Hyperpigmentation non surgical with PUFA injection, surgical treatment - Hyperpigmentation, Gingival Hyperpigmentaion | Phase 1 / Phase 2 | Active not recruiting | Suez Canal University | 30 | 2024-01-03 | 2025-07-16 |
| Novel Approach to Increase EPA and DHA Levels Meldonium + PUFA, PUFA + meldonium, PUFA supplementation only - Lipid Metabolism, Omega-3 Polyunsaturated Fatty Acids | Phase 1 | Completed | Riga Stradins University | 48 | 2023-04-06 | 2026-07-31 |
| Gut Microbiome Modification Through Dietary Intervention in Patients With Colorectal Cancer: Response to Surgery Dietary pattern : High-fiber diet rich in PUFA, Dietary pattern: Standard diet - Colorectal Cancer | Not applicable | Unknown | Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia | 50 | 2021-06-01 | 2022-07-27 |
| The ALA, DHA and EPA Esters in the Prevention of Cardiovascular Diseases. Fatty Acids, Unsaturated, Diagnostic Tests - Fatty Acids, Alpha-Linolenic Acid | Phase 3 | Unknown | Wroclaw Medical University | 200 | 2020-12-09 | 2021-02-08 |
| Treatment of Periodontitis in Menopausal Patients Polyunsaturated Fatty Acids, olive oil - Menopausal Patients, Chronic Periodontitis | Phase 4 | Completed | Hadir F. El-Dessouky | 20 | 2020-01-22 | 2024-02-12 |
| Antioxidant Use in Diabetes to Reduce Oxidative Stress N-acetyl cysteine, omega 6 Fish oil ( PUFA), Placebo - Ameliorating Oxidative Stress in Type 1 Diabetes | Early Phase 1 | Terminated | University of Maryland, Baltimore | 8 | 2018-11-01 | 2022-03-22 |
| Early DHA Supplementation in Very Low Birth Weight Infants Low dose PUFA, High dose PUFA, Placebo - Prematurity | Not applicable | Completed | Mead Johnson Nutrition | 30 | 2017-07-01 | 2019-05-07 |
| Effect of Fish Oil Enriched In Omega-11 Fatty Acid On Lipoprotein Metabolism In Adults control fish oil, LCMUFA-rich saury oil - Lipoprotein Metabolism, PCSK9 | Phase 2 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 37 | 2017-06-15 | 2020-08-12 |
| The Effects of Early Life PUFA and R-TFA on AD: A Systematic Review and Meta-analysis PUFA and R-TFA - Allergic Disorder | Completed | Sun Yat-sen University | 26 | 2017-03-15 | 2017-11-17 | |
| Effect of Plant Omega-3 and Omega-6 Fatty Acids on Exercise Performance corn syrup, Polyunsaturated fatty acid - Effect of Essential Fatty Acids on Exercise Performance | Not applicable | Unknown | University of Western Ontario, Canada | 18 | 2016-02-01 | 2016-01-13 |
| To Study the Immunomodulating Effects and Safety Profile of ω3 and ω6 PUFA Containing Intravenous Lipid Emulsion in Patients With Acute on Chronic Liver Failure ω3 PUFA (Polyunsaturated fatty acids) (10% Omegavan 100 ml), ω6 PUFA (Polyunsaturated fatty acids) (10% Intralipid 100 ml), No Lipid Emulsion/Placebo - Chronic Liver Failure | Not applicable | Completed | Institute of Liver and Biliary Sciences, India | 90 | 2016-02-01 | 2018-09-05 |
| Metabolic Effects of Egg Protein and Unsaturated Fat Intakes in Subjects With Hypertriglyceridemia Egg protein/unsaturated fatty acid, Control - Hypertriglyceridemia | Not applicable | Completed | Midwest Center for Metabolic and Cardiovascular Research | 28 | 2015-02-01 | 2018-05-15 |
| Effects of Omega-3 Supplementation on the Cytokine and Lipid Profiles in Patients With Chronic Chagas Cardiomyopathy Omega-3, Placebo Comparator - Chagas Cardiomyopathy | Early Phase 1 | Completed | Evandro Chagas Institute of Clinical Research | 40 | 2013-03-01 | 2016-09-09 |
| Omega-3 Fatty Acids in Elderly Patients With Acute Myocardial Infarction Pikasol, Corn oil - Myocardial Infarction, Heart Failure | Not applicable | Completed | Oslo University Hospital | 1027 | 2012-11-01 | 2020-08-19 |
| Safety and Efficacy of a Dietary Supplement in Females With Cellulite dietary supplement for cellulite (PUFA, resveratrol, lycopene, beta carotene, lutein), Viatmin E - Cellulite (Orange Peel Skin) | Not applicable | Terminated | dsm-firmenich Switzerland AG | 8 | 2011-05-01 | 2015-06-08 |
| Efficacy of Omega-3/Omega-6 Fatty Acids in Pre-school Children at Risk for ADHD omega-3/omega-6 fatty acids (PUFAs) - Children With ADHD Symptoms >90th Percentile (FBB-ADHS-V); no Beginning or Completion of Psychotherapeutically or Psychopharmalogical Treatment During the Study | Not applicable | Unknown | University of Cologne | 40 | 2010-09-01 | 2017-03-16 |
| Dietary Intervention With Phytochemicals and Polyunsaturated Fatty Acids in Prostate Cancer Patients Prostate cancer, phytochemical and PUFA - Prostate Cancer | Phase 1 / Phase 2 | Completed | University of Oslo | 86 | 2007-06-01 | 2013-12-19 |
| Polyunsaturated Fatty Acids (PUFA) in Diabetic Fatty Liver Polyunsaturated fatty acid (Opti-EPA), Placebo - Fatty Liver | Phase 2 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 37 | 2006-04-01 | 2018-02-23 |
| PUFA Augmentation in Treatment of Major Depression Polyunsaturated Fatty Acids (PUFA), Citalopram - Major Depression | Phase 3 | Completed | National Center for Complementary and Integrative Health (NCCIH) | 60 | 2003-09-01 | 2008-01-25 |
Cardiovascular Diseases (2) · Insulin Resistance (2) · Atrial Fibrillation (1) · Cellulite (1) · Chagas Cardiomyopathy (1) · Chagas Disease (1) · Chronic Periodontitis (1) · Colorectal Neoplasms (1) · Depression (1) · Depressive Disorder, Major (1) · Diabetes Mellitus, Type 2 (1) · End Stage Liver Disease (1) · Fatty Liver (1) · Heart Failure (1) · Hyperpigmentation (1)
Evandro Chagas Institute of Clinical Research (1) · Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia (1) · Hadir F. El-Dessouky (1) · Institute of Liver and Biliary Sciences, India (1) · Mead Johnson Nutrition (1) · Midwest Center for Metabolic and Cardiovascular Research (1) · National Center for Complementary and Integrative Health (NCCIH) (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · Oslo University Hospital (1) · Riga Stradins University (1) · Suez Canal University (1) · Sun Yat-sen University (1) · University of Cologne (1) · University of Maryland, Baltimore (1)
United States (5) · Brazil (2) · Norway (2) · Canada (1) · China (1) · Egypt (1) · Germany (1) · India (1) · Latvia (1) · Poland (1) · Saudi Arabia (1) · Spain (1)
Andrea S Sousa, MD PhD (1) · Are A Kalstad, MD (1) · Arthur J. McCullough, M.D. (1) · Doris M Hexsel, MD (1) · Dr Anand Kulkarni V, MD (1) · Harald Arnesen, MD Phd (1) · Ilze Konrade, PhD, MD (1) · Kevin C Maki, PhD (1) · Kristian Laake, MD (1) · Lev Gertsik, MD (1) · Li Cai, PhD (1)
PMID 24216069, PMID 24583757, PMID 24928284, PMID 27406859, PMID 28515160, PMID 28599665, PMID 31881852, PMID 33191772, PMID 33358843, PMID 33650449, PMID 34742136, PMID 34817851, PMID 37058600, PMID 38510979, PMID 42046081
U01DK061732 (1)