11 completed, 8 unknown, 4 terminated, 2 recruiting. 27 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 27 | Completed 11, Unknown 8, Terminated 4, Recruiting 2, Not yet recruiting 1, Withdrawn 1 |
Follow esmolol: new trials by email Literature Review of esmolol trials Research Report on esmolol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Esmolol Versus Sufentanil on the Quality of Post-cholecystectomy Recovery Laparoscopic Anaesthesia With Orotracheal Intubation on an Outpatient Basis Esmolol Hcl 10Mg/Ml Inj, Sufentanil 5 mcg - Laparoscopic Cholecystectomy Surgery | Phase 4 | Recruiting | University Hospital, Limoges | 120 | 2025-10-29 | 2026-04-13 |
| Effect of Opioid-free Anaesthesia on Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal Surgery Dexmedetomidine, Esketamine, Esmolol - Delirium - Postoperative, Opioid-Free Anaesthesia | Phase 4 | Not yet recruiting | Qianfoshan Hospital | 406 | 2025-05-20 | 2025-05-06 |
| Impact of Administration of Esmolol on Nociception Level-guided Control of Nociception. Esmolol Hydrochloride, Saline - Opioid Use, Unspecified, Anesthesia | Phase 4 | Unknown | Ciusss de L'Est de l'Île de Montréal | 64 | 2024-04-16 | 2024-07-16 |
| Effects of Low-dose Esmolol on Myocardial Injury After Non-cardiac Surgery in Elderly Frail Patients Esmolol, Placebo Comparator: Placebo Comparator:normal saline(0.9%) - Frailty, Esmolol | Phase 4 | Recruiting | Yongtao Sun | 2000 | 2023-02-07 | 2023-03-29 |
| Effect of Esmolol on Perioperative Stress Reaction Esmolol, saline - Esmolol, Stress Reaction | Phase 4 | Unknown | Xiumei Song | 46 | 2023-02-01 | 2023-01-23 |
| Assessment of Intravenous Rate Control Response in Atrial Fibrillation Trial (AIRCRAFT) Beta-blocker strategy, Calcium channel blocker strategy, Physician preference strategy - Atrial Fibrillation | Phase 4 | Withdrawn | Boston University | 2021-12-01 | 2021-12-15 | |
| Esmolol for Myocardial Protection in Hypertrophic Obstructive Cardiomyopathy Esmolol, Placebo - Hypertrophic Obstructive Cardiomyopathy | Phase 4 | Unknown | Meshalkin Research Institute of Pathology of Circulation | 80 | 2021-10-06 | 2021-10-11 |
| Dose Esmolol Infusion Have an Adjuvant Effect to TAP Block for Pain Control in Laparoscopic Cholecystectomy. Esmolol - Postoperative Pain | Phase 4 | Completed | Benha University | 60 | 2021-01-19 | 2021-10-01 |
| Role of Intraoperative Beta Blocker for Morbid Obese Patients Undergoing Laparoscopic Bariatric Surgery Esmolol - Intraoperative Awareness, Postoperative Pain | Phase 4 | Unknown | Ain Shams University | 60 | 2019-11-01 | 2019-11-25 |
| Esmolol for the Treatment of Hypertension After Intracerebral Hemorrhage Study (ETHICHS) Brevibloc, 10 Mg/mL Intravenous Solution, Nitroprusside, Sodium - Hemorrhagic Stroke | Phase 4 | Terminated | Cristália Produtos Químicos Farmacêuticos Ltda. | 20 | 2019-04-18 | 2023-02-09 |
| Evaluation of Early CRRT InTerventions in Patients With ECMO(ELITE) Simultaneous CRRT, Conventional-indication CRRT, Esmolol - Cardiogenic Shock | Phase 4 | Completed | Beijing Anzhen Hospital | 131 | 2018-12-18 | 2024-04-24 |
| The Effects of Lidocaine and Esmolol on Attenuation of Hemodynamic Response to Orotracheal Intubation Esmolol, Lidocaine - Hemodynamic Instability | Phase 4 | Unknown | Hospital de Base | 80 | 2018-07-01 | 2019-05-29 |
| Glucagon's Cardiovascular Effects With and Without Beta-blocker-induced Cardioinhibition Glucagon, Esmolol, Physiologic saline - glucagon dummy - Drug Overdose, Overdose of Beta-adrenergic Blocking Drug | Phase 4 | Completed | University Hospital Bispebjerg and Frederiksberg | 10 | 2018-06-01 | 2019-10-17 |
| Effect of Controlled Hypotension on Cerebral Oxygen Saturation Esmolol Hydrochloride, Remifentanil Hydrochloride - Hypotension Drug-Induced, Cerebral Oxygen Saturation | Phase 4 | Completed | Istanbul University | 150 | 2016-11-01 | 2021-09-01 |
| Hemodynamic Response to Intubation Dexmedetomidine, Esmolol, Placebo - Intubation | Phase 4 | Unknown | Ufuk University | 60 | 2016-06-01 | 2016-07-26 |
| Analgesic Effect of Intraoperative Esmolol in Mastectomies Placebo group, Esmolol group - Postoperative Pain | Phase 4 | Completed | Hospital de Base | 60 | 2015-06-01 | 2017-04-05 |
| Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy Lidocaine, Esmolol, Paracetamol - Gall Stone Disease | Phase 4 | Completed | B.P. Koirala Institute of Health Sciences | 90 | 2015-01-01 | 2018-11-30 |
| The Effects of the Drugs Used in Hypotensive Anaesthesia on Cochlea Dexmedetomidine, esmolol - Anesthesia; Adverse Effect, Reflex, Abnormal | Phase 4 | Completed | TC Erciyes University | 47 | 2014-01-01 | 2014-11-10 |
| Effect of Esmolol on Pain Due to Rocuronium Lidocaine, Esmolol, rocuronium - Injection Site Irritation | Phase 4 | Completed | Ankara Diskapi Training and Research Hospital | 90 | 2013-03-01 | 2019-10-04 |
| A Comparison of Esmolol and Remifentanil to Reduce Blood Loss Remifentanil, Esmolol - Deviation Septum Nasal | Phase 4 | Unknown | Diskapi Teaching and Research Hospital | 60 | 2012-07-01 | 2012-12-19 |
Showing 20 of 27. Sign in to see all of them.
Agnosia (4) · Pain, Postoperative (4) · Hypertension (2) · Pain (2) · Acute Coronary Syndrome (1) · Airway Obstruction (1) · Angina Pectoris (1) · Atrial Fibrillation (1) · Cardiomyopathy, Hypertrophic (1) · Constipation (1) · Coronary Artery Disease (1) · Drug Overdose (1) · Emergence Delirium (1) · Fractures, Stress (1) · Frailty (1)
Cedars-Sinai Medical Center (3) · Diskapi Teaching and Research Hospital (2) · Hospital de Base (2) · Ain Shams University (1) · Ankara Diskapi Training and Research Hospital (1) · B.P. Koirala Institute of Health Sciences (1) · Beijing Anzhen Hospital (1) · Benha University (1) · Boston University (1) · Ciusss de L'Est de l'Île de Montréal (1) · Cristália Produtos Químicos Farmacêuticos Ltda. (1) · Istanbul University (1) · Meshalkin Research Institute of Pathology of Circulation (1) · Nanjing Medical University (1) · Qianfoshan Hospital (1)
Turkey (Türkiye) (6) · China (4) · United States (4) · Brazil (3) · Canada (2) · Egypt (2) · Denmark (1) · France (1) · Italy (1) · Nepal (1) · Russia (1)
Roya Yumul, MD, PhD (2) · Allan Walkey, MD (1) · Asish Subedi, MD (1) · Demet Altun (1) · Dilek Yazicioglu (1) · Fabricio T Mendonca, MD, TSA (1) · Gunhan Gokahmetoglu, M.D (1) · Jianzeng Dong, PhD., Md. (1) · Jinwan Guo, Master (1) · Kasper M Petersen, MD (1) · Liang Guo, M.D. (1) · Ling Dong, M.D. (1) · Ronald H Wender, MD (1)
PMID 25886340, PMID 31684867, PMID 33103603, PMID 33831899, PMID 34636226, PMID 35986410, PMID 38504166, PMID 40721742, PMID 42425722