7 completed, 3 recruiting, 2 not yet recruiting, 2 terminated. 15 Phase 2, 4 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 15 | Completed 7, Recruiting 3, Not yet recruiting 2, Terminated 2, Unknown 1 |
| Phase 3 | 4 | Completed 1, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow Dextrose: new trials by email Literature Review of Dextrose trials Research Report on Dextrose
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Additive On-Demand Sildenafil vs. Dextrose Candy on Maximum Exercise Capacity in Pulmonary Arterial Hypertension Dextrose, Sildenafil 20mg - Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH) | Phase 2 / Phase 3 | Recruiting | Silvia Ulrich | 20 | 2026-10-26 | 2026-11-04 |
| Effectiveness of Dextrose Pleurodesis for the Management of Post-Operative Air Leak 50% Dextrose Pleurodesis, Standard of Care Chest Drainage - Post Operative Pulmonary Air Leak | Phase 2 | Not yet recruiting | Thomas Jefferson University | 80 | 2026-06-01 | 2026-04-23 |
| Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery Aprepitant, Placebo - Spinal Fusion, Nausea and Vomiting, Postoperative | Phase 2 | Recruiting | IWK Health Centre | 100 | 2025-03-17 | 2026-04-27 |
| Sirolimus Treatment Of Patients With SLE Sirolimus, Placebo - Lupus Erythematosus, Systemic | Phase 2 | Not yet recruiting | State University of New York - Upstate Medical University | 220 | 2025-01-01 | 2023-06-05 |
| 5-HTP and Creatine for Depression R33 Phase Low Dose 5-hydroxytryptophan, High Dose 5-hydroxytryptophan, Low Dose Creatine Monohydrate - Major Depressive Disorder | Phase 2 | Recruiting | University of Utah | 106 | 2023-09-28 | 2026-08-27 |
| The Impact of Air Travel on Passenger Cognitive Functions Citicoline, Cytochrome C6, Sodium Chloride Oral Product - Air Travel | Phase 2 / Phase 3 | Unknown | Dinara Zhumanbayeva | 50 | 2021-06-01 | 2021-03-17 |
| Energy Metabolism in Thyroidectomized Patients Levothyroxine, Liothyronine, Placebo - Thyroid Goiter, Hypothyroidism | Phase 2 | Completed | Virginia Commonwealth University | 13 | 2020-10-28 | 2024-06-14 |
| The Impact of a Preoperative Nerve Block on the Consumption of Sevoflurane in Total Shoulder Arthroplasty Ropivacaine, Dextrose - Rotator Cuff Injuries, Anesthesia; Functional | Phase 2 / Phase 3 | Terminated | University of Alberta | 17 | 2019-08-01 | 2024-06-06 |
| Glutamine for the Prevention of Radiation Toxicity in Subjects Conserving Therapy Glutamine, Placebo - Breast Cancer | Phase 2 | Terminated | University of Arkansas | 14 | 2014-06-01 | 2019-05-29 |
| Caudal Epidural Injection of Dextrose For Low Back Pain Saline, Dextrose - Back Pain Lower Back Chronic | Phase 2 | Completed | Smigel, Liza, M.D. | 35 | 2012-02-01 | 2018-04-30 |
| Multi-dose Pharmacokinetics and Dose Ranging of Inositol in Premature Infants (INS-2) Inositol lower volume, Inositol mid-level volume, Inositol high volume - Infant, Newborn, Infant, Low Birth Weight | Phase 2 | Completed | NICHD Neonatal Research Network | 125 | 2010-01-01 | 2022-06-14 |
| Efficacy of Injection Therapy for Lateral Epicondylosis Dextrose prolotherapy, PrT-DMS, Platelet Rich Plasma injection - Tennis Elbow | Phase 2 | Completed | University of Wisconsin, Madison | 31 | 2009-06-01 | 2019-02-18 |
| Comparing Soybean Oil-Based (Intralipid) With an Olive Oil-Based (ClinOleic) Lipid Emulsion on Healthy Volunteers Intralipid, ClinOleic, Dextrose - Diseases, Metabolic, Insulin Sensitivity | Phase 2 / Phase 3 | Completed | Emory University | 12 | 2008-06-01 | 2014-12-31 |
| Lactulose Supplementation in Premature Infants Lactulose, Dextrose - Necrotizing Enterocolitis, Sepsis | Phase 2 | Completed | Bnai Zion Medical Center | 28 | 2005-02-01 | 2008-02-15 |
| Joint Injections for Osteoarthritic Knee Pain Dextrose Prolotherapy, Saline Prolotherapy, At-home physical therapy exercise group - Osteoarthritis | Phase 1 / Phase 2 | Completed | University of Wisconsin, Madison | 98 | 2004-07-01 | 2019-02-15 |
Premature Birth (2) · Agnosia (1) · Breast Neoplasms (1) · Bronchopulmonary Dysplasia (1) · Depressive Disorder, Major (1) · Enterocolitis, Necrotizing (1) · Goiter (1) · Hypothyroidism (1) · Insulin Resistance (1) · Lupus Erythematosus, Systemic (1) · Metabolic Diseases (1) · Osteoarthritis (1) · Postoperative Nausea and Vomiting (1) · Pulmonary Arterial Hypertension (1) · Retinopathy of Prematurity (1)
University of Wisconsin, Madison (2) · Bnai Zion Medical Center (1) · Dinara Zhumanbayeva (1) · Emory University (1) · IWK Health Centre (1) · NICHD Neonatal Research Network (1) · Silvia Ulrich (1) · Smigel, Liza, M.D. (1) · State University of New York - Upstate Medical University (1) · Thomas Jefferson University (1) · University of Alberta (1) · University of Arkansas (1) · University of Utah (1) · Virginia Commonwealth University (1)
United States (8) · Canada (2) · Israel (1) · Switzerland (1)
Abbot R. Laptook, MD (1) · Abhik Das, PhD (1) · Angeliki M Stamatouli, MD (1) · Arcangelo F Carta, Dr. med. (1) · Arieh Riskin, MD (1) · Barbara J. Stoll, MD (1) · Brenda B. Poindexter, MD MS (1) · Dale L. Phelps, MD (1) · David P Rabago, MD (1) · David P. Rabago, MD (1) · Edward F Bell, MD (1) · Guillermo Umpierrez, MD (1) · John Wilson, MD (1) · Kathleen A. Kennedy, MD MPH (1)
PMID 21832112, PMID 22515800, PMID 23690322, PMID 24635447, PMID 27074126
K23AT001879 (1), M01RR008084 (1), R21DK122310 (1), U10HD021364 (1), U10HD021373 (1), U10HD021385 (1), U10HD027851 (1), U10HD027853 (1), U10HD027856 (1), U10HD027871 (1), U10HD027880 (1), U10HD027904 (1), U10HD034216 (1), U10HD036790 (1), U10HD040492 (1)