45 completed, 7 unknown, 6 recruiting, 5 active not recruiting. 26 Not applicable, 15 Phase 2, 11 Phase 3, 10 Early Phase 1, 9 Phase 4.
Follow Dextrose: new trials by email Literature Review of Dextrose trials Research Report on Dextrose
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Additive On-Demand Sildenafil vs. Dextrose Candy on Maximum Exercise Capacity in Pulmonary Arterial Hypertension Dextrose, Sildenafil 20mg - Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH) | Phase 2 / Phase 3 | Recruiting | Silvia Ulrich | 20 | 2026-09-01 | 2026-09-17 |
| Effect of Trilaciclib in the Prevention of Myelosupression in Subjects With Limited-stage Small Cell Lung Cancer Trilaciclib, Saline (0.9% NaCl) - Limited Stage Small Cell Lung Cancer | Phase 3 | Recruiting | Pharmacosmos A/S | 120 | 2026-09-01 | 2026-10-02 |
| Sleep Loss and Circadian Misalignment - Mechanisms of Insulin Resistance Metyrapone And Hydrocortisone, Dextrose, insulin - Shift Work Schedule, Circadian Rhythm | Phase 4 | Recruiting | Washington State University | 48 | 2026-07-16 | 2026-09-18 |
| Effectiveness of Dextrose Pleurodesis for the Management of Post-Operative Air Leak 50% Dextrose Pleurodesis, Standard of Care Chest Drainage - Post Operative Pulmonary Air Leak | Phase 2 | Not yet recruiting | Thomas Jefferson University | 80 | 2026-06-01 | 2026-04-23 |
| Impact of Insulin Deprivation and Hyperglycemia on Plasma Protein Synthesis in People With Type 1 Diabetes Mellitus Muscle Biopsy, Jell-O with Amino acids, Dextrose - Type 1 Diabetes | Not applicable | Withdrawn | Mayo Clinic | 2026-06-01 | 2026-08-05 | |
| Effects of Three Carbohydrate Beverages on Resistance Training Performance Dextrose, Maltodextrin, Highly Branched Cyclic Dextrin - Resistance Training, Sports Nutrition | Not applicable | Completed | Istanbul Gelisim University | 38 | 2026-05-04 | 2026-10-15 |
| The Effects of Ketone Supplements With Carbohydrates on Cycling Performance Above Lactate Threshold Ketone supplementation, Carbohydrate - Exogenous Ketosis | Early Phase 1 | Not yet recruiting | University of Oklahoma | 15 | 2025-11-17 | 2025-11-04 |
| Comparison of the Effectiveness of 5% and 10% Dextrose Treatments in Patients With Chronic Shoulder Pain: Ultrasound-Guided Perineural Injection dextrose - Chronic Shoulder Pain | Not applicable | Completed | Ankara City Hospital Bilkent | 120 | 2025-07-09 | 2026-02-23 |
| Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery Aprepitant, Placebo - Spinal Fusion, Nausea and Vomiting, Postoperative | Phase 2 | Recruiting | IWK Health Centre | 100 | 2025-03-17 | 2026-04-27 |
| Effectiveness of Creatine on Pain, Fatigue, and Muscle Architectural Variables in Patients Witg Fibromyalgia. Creatine, Dextrose - Fibromyalgia | Not applicable | Completed | Camilo Jose Cela University | 80 | 2025-02-12 | 2026-07-29 |
| Assessments of Metabolic Responses to Acute Oral Administration of Sucrose, Glucose, and Fructose Sucrose, Glucose, Fructose - Gastrointestinal Hormones, Glycemic Control | Not applicable | Active not recruiting | University Hospital, Basel, Switzerland | 20 | 2025-02-06 | 2026-09-03 |
| Sirolimus Treatment Of Patients With SLE Sirolimus, Placebo - Lupus Erythematosus, Systemic | Phase 2 | Not yet recruiting | State University of New York - Upstate Medical University | 220 | 2025-01-01 | 2023-06-05 |
| Efficacy of 50% Oral Dextrose As Pain Relief in Newborns Before Bladder Catheterization Dextrose, normal water - Pain Management, Neonatal Pain | Not applicable | Enrolling by invitation | Oman Medical Speciality Board | 90 | 2024-10-09 | 2024-10-10 |
| Low-Dose IL-2 For The Reduction Of Vascular Inflammation In ACS -Clinical Outcomes & Follow-up Study Aldesleukin, Dextrose 5% in water - Acute Coronary Syndromes | Recruiting | Cambridge University Hospitals NHS Foundation Trust | 60 | 2024-06-01 | 2024-06-10 | |
| 5-HTP and Creatine for Depression R33 Phase Low Dose 5-hydroxytryptophan, High Dose 5-hydroxytryptophan, Low Dose Creatine Monohydrate - Major Depressive Disorder | Phase 2 | Recruiting | University of Utah | 106 | 2023-09-28 | 2026-08-27 |
| A Study of MK-5720 in Participants With Schizophrenia (MK-5720-001) MK-5720, Placebo to MK-5720, MK-8189 - Schizophrenia | Phase 1 | Completed | Merck Sharp & Dohme LLC | 17 | 2023-09-15 | 2025-03-04 |
| A Clinical Study of Intismeran Autogene (V940) Plus Pembrolizumab in People With High-Risk Melanoma (V940-001) Intismeran autogene, Pembrolizumab, Placebo - Melanoma | Phase 3 | Active not recruiting | Merck Sharp & Dohme LLC | 1089 | 2023-07-19 | 2025-09-24 |
| Dextrose Therapy on Physical Therapy in Subdeltoid Bursitis Dextrose, Normal saline - Subdeltoid Bursitis, Injection | Phase 4 | Unknown | Taipei Medical University | 46 | 2023-06-20 | 2023-06-27 |
| Glucagon Suppression by Hyperglycemia in the Presence and Absence of Amino Acid Infusion Dextrose, Clinisol 15% - Healthy, Type 2 Diabetes | Phase 4 | Active not recruiting | Mayo Clinic | 30 | 2023-05-30 | 2026-02-13 |
| BaRiatric Surgery AnD FRUctose Handeling In Obese subjecTs fructose - Insulin Resistance | Not applicable | Unknown | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 20 | 2023-02-05 | 2023-02-08 |
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Diabetes Mellitus, Type 2 (5) · Diabetes Mellitus, Type 1 (4) · Insulin Resistance (4) · Obesity (4) · Hyperglycemia (3) · Pain (3) · Premature Birth (3) · Acute Pain (2) · Agnosia (2) · Breast Neoplasms (2) · Depressive Disorder, Major (2) · Diabetes Mellitus (2) · Fibromyalgia (2) · Hypoglycemia (2) · Motor Activity (2)
Merck Sharp & Dohme LLC (6) · University of Chicago (5) · Mayo Clinic (3) · Bioenergy Life Science, Inc. (2) · Kansas State University (2) · Taipei Medical University (2) · University of Colorado, Denver (2) · University of Sao Paulo (2) · University of Wisconsin, Madison (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Ankara City Hospital Bilkent (1) · Bnai Zion Medical Center (1) · Butler Hospital (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Camilo Jose Cela University (1)
United States (39) · Canada (7) · Turkey (Türkiye) (6) · Brazil (5) · United Kingdom (5) · Switzerland (4) · Taiwan (4) · Argentina (3) · Australia (3) · Germany (3) · Israel (3) · Spain (3) · Chile (2) · Colombia (2) · France (2)
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PMID 18182958, PMID 20452743, PMID 21832112, PMID 22515800, PMID 23690322, PMID 24635447, PMID 25527165, PMID 27074126, PMID 2712610, PMID 28276900, PMID 28701493, PMID 28973414, PMID 29884456, PMID 30103342, PMID 30125349, PMID 31668830, PMID 33838870, PMID 35390172, PMID 35439521, PMID 35747889, PMID 38030971, PMID 38710978, PMID 41712301
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