3 completed, 2 active not recruiting, 2 recruiting, 2 terminated. 11 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 3, Active not recruiting 2, Recruiting 2, Terminated 2, Unknown 2 |
| Phase 2 | 4 | Completed 1, Recruiting 1, Terminated 1, Unknown 1 |
Follow Dextrose: new trials by email Literature Review of Dextrose trials Research Report on Dextrose
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Additive On-Demand Sildenafil vs. Dextrose Candy on Maximum Exercise Capacity in Pulmonary Arterial Hypertension Dextrose, Sildenafil 20mg - Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH) | Phase 2 / Phase 3 | Recruiting | Silvia Ulrich | 20 | 2026-10-26 | 2026-11-04 |
| Effect of Trilaciclib in the Prevention of Myelosupression in Subjects With Limited-stage Small Cell Lung Cancer Trilaciclib, Saline (0.9% NaCl) - Limited Stage Small Cell Lung Cancer | Phase 3 | Recruiting | Pharmacosmos A/S | 120 | 2026-09-01 | 2026-10-02 |
| A Clinical Study of Intismeran Autogene (V940) Plus Pembrolizumab in People With High-Risk Melanoma (V940-001) Intismeran autogene, Pembrolizumab, Placebo - Melanoma | Phase 3 | Active not recruiting | Merck Sharp & Dohme LLC | 1089 | 2023-07-19 | 2025-09-24 |
| Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49) pembrolizumab, paclitaxel, nab-paclitaxel - Breast Neoplasms | Phase 3 | Active not recruiting | Merck Sharp & Dohme LLC | 342 | 2021-06-18 | 2026-07-22 |
| The Impact of Air Travel on Passenger Cognitive Functions Citicoline, Cytochrome C6, Sodium Chloride Oral Product - Air Travel | Phase 2 / Phase 3 | Unknown | Dinara Zhumanbayeva | 50 | 2021-06-01 | 2021-03-17 |
| Hypertonic Dextrose Versus Corticosteroid Intra-Articular Injections for the Treatment of Trapeziometacarpal Arthritis Dextrose, Methylprednisolone Acetate 40 MG/ML - Pain, Satisfaction, Patient | Phase 3 | Unknown | Christine M. Kleinert Institute for Hand and Microsurgery | 130 | 2021-04-01 | 2021-03-16 |
| The Impact of a Preoperative Nerve Block on the Consumption of Sevoflurane in Total Shoulder Arthroplasty Ropivacaine, Dextrose - Rotator Cuff Injuries, Anesthesia; Functional | Phase 2 / Phase 3 | Terminated | University of Alberta | 17 | 2019-08-01 | 2024-06-06 |
| Myocardial Protection With Phosphocreatine in High-RIsk Cardiac SurgEry Patients Phosphocreatine sodium tetrahydrate after anaesthesia induction, 5% Glucose after anaesthesia induction, Phosphocreatine sodium tetrahydrate added to cardioplegia - Cardiac Surgical Procedures, Heart Valve Prosthesis Implantation | Phase 3 | Completed | Meshalkin Research Institute of Pathology of Circulation | 120 | 2016-06-01 | 2021-07-01 |
| Creatine Safety, Tolerability, & Efficacy in Huntington's Disease (CREST-E) Creatine Monohydrate, Placebo - Huntington's Disease | Phase 3 | Terminated | Massachusetts General Hospital | 553 | 2009-09-01 | 2016-03-11 |
| Comparing Soybean Oil-Based (Intralipid) With an Olive Oil-Based (ClinOleic) Lipid Emulsion on Healthy Volunteers Intralipid, ClinOleic, Dextrose - Diseases, Metabolic, Insulin Sensitivity | Phase 2 / Phase 3 | Completed | Emory University | 12 | 2008-06-01 | 2014-12-31 |
| Sequential Use of Fluoxetine for Smokers With Elevated Depressive Symptoms Fluoxetine, Dextrose - Major Depressive Disorder, Nicotine Dependence | Phase 3 | Completed | Butler Hospital | 206 | 2008-04-01 | 2018-10-16 |
Breast Neoplasms (1) · Depression (1) · Depressive Disorder, Major (1) · Huntington Disease (1) · Insulin Resistance (1) · Melanoma (1) · Metabolic Diseases (1) · Mitochondrial Diseases (1) · Neoplasm Metastasis (1) · Pain (1) · Parkinson Disease 4, Autosomal Dominant Lewy Body (1) · Patient Satisfaction (1) · Pulmonary Arterial Hypertension (1) · Rotator Cuff Injuries (1) · Smoking Cessation (1)
Merck Sharp & Dohme LLC (2) · Butler Hospital (1) · Christine M. Kleinert Institute for Hand and Microsurgery (1) · Dinara Zhumanbayeva (1) · Emory University (1) · Massachusetts General Hospital (1) · Meshalkin Research Institute of Pathology of Circulation (1) · Pharmacosmos A/S (1) · Silvia Ulrich (1) · University of Alberta (1)
United States (6) · Canada (4) · Australia (3) · Argentina (2) · Brazil (2) · Chile (2) · Colombia (2) · France (2) · Germany (2) · Greece (2) · Israel (2) · Italy (2) · Japan (2) · New Zealand (2) · Poland (2)
Arcangelo F Carta, Dr. med. (1) · Diana Rosas, MD, MS (1) · Evgeny V. Fominskiy, MD PhD (1) · Giovanni Schifitto, MD (1) · Guillermo Umpierrez, MD (1) · Lora Pencheva, MD (1) · Rakesh V Sondekoppam, MD (1) · Richard A. Brown, Ph.D. (1) · Silvia Ulrich, Prof. Dr. med. (1) · Steven M Hersch, MD, PhD (1) · Tuna Ozyurekoglu, MD (1) · Vivian HY Ip, MD (1)
PMID 18182958, PMID 20452743, PMID 21832112, PMID 2712610, PMID 28701493, PMID 30103342, PMID 35747889, PMID 38030971
2023 (2), R01DA023190 (1), U01AT000613 (1)