14 completed, 4 unknown, 3 terminated, 2 not yet recruiting. 25 Phase 3, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 25 | Completed 14, Unknown 4, Terminated 3, Not yet recruiting 2, Active not recruiting 1, Recruiting 1 |
| Phase 2 | 6 | Completed 3, Active not recruiting 1, Terminated 1, Unknown 1 |
Follow Botulinum Toxins: new trials by email Literature Review of Botulinum Toxins trials Research Report on Botulinum Toxins
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Botulinum TOXin Type A in the Treatment of Buerger's Disease BOTOX INJECTION - Buerger Disease, Raynaud Syndrome | Phase 3 | Not yet recruiting | University Hospital, Toulouse | 8 | 2027-01-01 | 2026-07-23 |
| Botulinum Toxin Injection After Sternotomies to Improve Scar Aspect and Impact Botulinum toxin injection - Sternotomy Closure,Open Heart Surgery | Phase 3 | Not yet recruiting | University Hospital, Bordeaux | 50 | 2025-07-05 | 2025-06-10 |
| Cyclops Syndrome After Anterior Cruciate Ligament Reconstruction Botulinum toxin, Placebo - Hamstring Contractures | Phase 3 | Terminated | GCS Ramsay Santé pour l'Enseignement et la Recherche | 13 | 2024-07-18 | 2026-06-05 |
| Injection of Botulinum Toxin for Thumb Carpometacarpal Arthritis Botulinum toxin, Standard-of-care corticosteroid injections - Carpometacarpal Sprain, Thumb Sprain | Phase 3 | Recruiting | Rhode Island Hospital | 50 | 2023-08-27 | 2024-11-20 |
| Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization Botulinum Toxin, Normal saline - Scar, Hypertrophic Scar | Phase 2 / Phase 3 | Active not recruiting | Henry Ford Health System | 12 | 2022-06-01 | 2026-01-15 |
| Efficacy of Botulinum Toxin A in the Treatment of Bruxism-related Symptomatology Botulinum toxin injection, QOL-Brux, Muscular strength of the jaw - Bruxism | Phase 3 | Terminated | Centre Hospitalier Universitaire Dijon | 1 | 2022-05-25 | 2024-08-26 |
| Treatment of Moderate to Severe Lateral Canthal Lines botulinum toxin, Placebo - Lateral Canthal Lines | Phase 3 | Completed | Galderma R&D | 303 | 2020-02-10 | 2023-06-18 |
| Treatment of Moderate to Severe Glabellar Lines botulinum toxin, Placebo - Glabellar Frown Lines | Phase 3 | Completed | Galderma R&D | 300 | 2020-02-10 | 2023-06-18 |
| The Efficacy and Molecular Mechanism of Botulinum Toxin in the Reduction of Breast Reduction Mammoplasty Scar Formation Botulinum Toxins, Normal saline - Scar, Hypertrophic Scar | Phase 2 / Phase 3 | Completed | Henry Ford Health System | 22 | 2019-06-10 | 2025-06-15 |
| A Phase III Study to Evaluate Efficacy of Botulinum Toxin for Treating Epicondylitis Injection, botulinum toxin + corticoid, Injection, placebo of toxin + corticoid, Injection, botulinum toxin + placebo corticoid - Epicondylitis | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 33 | 2019-04-19 | 2023-09-21 |
| Early Postoperative Prevention and Treatment of Median Sternotomy Scars With Botulinum Toxin Type A Injection Botulinum toxin type A, normal saline - Scar | Phase 2 / Phase 3 | Completed | Xijing Hospital | 17 | 2016-10-01 | 2018-01-25 |
| Comparative Hybrid Effects of Combining BoNT-A With Robot-assisted or Mirror Therapy for U/E Spasticity Stroke Patients Botulinum Toxin Type A, Robot-assisted therapy, Mirror therapy - Stroke | Phase 3 | Completed | Chang Gung Memorial Hospital | 37 | 2016-05-02 | 2018-07-18 |
| Botulinim Toxin Type A Injections by Different Guidance in Stroke Patients With Spasticity on Lower Extremities Botulinum toxin type A - Cerebrovascular Accident | Phase 3 | Unknown | Chang Gung Memorial Hospital | 40 | 2015-10-01 | 2015-10-14 |
| Botulinum Toxin Injection Into Epicardial Fat Pads to Prevent Atrial Fibrillation in Patients Undergoing Cardiac Surgery botulinum toxin injection, 0.9% normal saline injection, Implantable loop recorder - Atrial Fibrillation | Phase 2 / Phase 3 | Unknown | Meshalkin Research Institute of Pathology of Circulation | 170 | 2015-09-01 | 2017-09-08 |
| Efficacy of Botulinum Toxin In Scleroderma-Associated Raynaud's Syndrome Onabotulinumtoxin A, sterile saline solution - Scleroderma, Raynaud's Syndrome | Phase 3 | Completed | Johns Hopkins University | 40 | 2015-01-01 | 2016-12-22 |
| Ultrasound and EMG Guided Botox Injection for the Treatment of Non-Relaxing Puborectalis Syndrome botulinum toxin - Non-relaxing Puborectalis Syndrome | Phase 2 / Phase 3 | Terminated | Karen Noblett | 7 | 2013-01-01 | 2021-11-03 |
| Botulinim Toxin Type A Injections by Different Guidance in Stroke Patients With Spasticity on Upper Extremities Botulinum Toxin Type A - Cerebrovascular Accident | Phase 3 | Unknown | Chang Gung Memorial Hospital | 40 | 2012-09-01 | 2016-03-30 |
| Lateral Canthal Rhytides With Medium Depth Chemical Peel With or Without Pretreatment With Botulinum Toxin A Botulinum Toxin, Chemical Peel Only - Wrinkles | Phase 3 | Completed | Loyola University | 26 | 2011-09-01 | 2017-09-11 |
| Botulinum Toxin Injections by Ultrasounds Guidance and Stretching Exercise in Spastic Toe Clawing Botulinum Toxin Type A, Stretching exercise - Cerebrovascular Accident | Phase 3 | Completed | Chang Gung Memorial Hospital | 30 | 2010-08-01 | 2015-10-26 |
| Efficacy Study of Selective Tibial Neurotomy in the Treatment of the Spastic Equinovarus Foot Among Adult Hemiplegic Patients Selective tibial neurotomy, Botulinum toxin injection - Spastic Equinovarus Foot, Stroke | Phase 3 | Completed | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 16 | 2008-10-01 | 2011-12-23 |
Showing 20 of 25. Sign in to see all of them.
Stroke (5) · Cicatrix (4) · Muscle Spasticity (4) · Cicatrix, Hypertrophic (2) · Raynaud Disease (2) · Atrial Fibrillation (1) · Botulism (1) · Breast Diseases (1) · Bruxism (1) · Cerebral Palsy (1) · Constipation (1) · Dyspareunia (1) · Gigantomastia (1) · Hammer Toe Syndrome (1) · Keloid (1)
Chang Gung Memorial Hospital (4) · Mentor Worldwide, LLC (3) · Galderma R&D (2) · Henry Ford Health System (2) · Assistance Publique - Hôpitaux de Paris (1) · Centre Hospitalier Universitaire Dijon (1) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1) · GCS Ramsay Santé pour l'Enseignement et la Recherche (1) · Hospices Civils de Lyon (1) · Johns Hopkins University (1) · Karen Noblett (1) · Loyola University (1) · Meshalkin Research Institute of Pathology of Circulation (1) · Rhode Island Hospital (1) · Tehran University of Medical Sciences (1)
United States (11) · France (6) · Taiwan (4) · Canada (2) · Belgium (1) · China (1) · Iran (1) · Russia (1)
Pong Ya-Ping, MD (3) · Corey Maas, MD (2) · David Ozog, MD (2) · Alexandre Hardy, MD (1) · Benjamin Bollens, Doctor (1) · Corey Maas (1) · Jen-Wen Hung (1) · Julie Malloizel-Delaunay, MD (1) · Karen Noblett, MD (1) · Rebecca Tung, MD (1) · Scott D Lifchez, MD (1)
PMID 10077078, PMID 10896696, PMID 11242330, PMID 11348456, PMID 12845617, PMID 16777777, PMID 18065878, PMID 18534768, PMID 18555763, PMID 18843115, PMID 19215252, PMID 19341651, PMID 19802513, PMID 20009818, PMID 20440184, PMID 21332916, PMID 22090252, PMID 22177632, PMID 22907286, PMID 23027220, PMID 23102873, PMID 24501476, PMID 24898579, PMID 25592185, PMID 27639820, PMID 28426903, PMID 28539239, PMID 28654594, PMID 29401161, PMID 30548742, PMID 31155638, PMID 31164358, PMID 31513335, PMID 32813130, PMID 3809245
2017 (1)