6 completed, 2 recruiting, 2 unknown, 1 withdrawn. 11 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 11 | Completed 6, Recruiting 2, Unknown 2, Withdrawn 1 |
Follow Ativan: new trials by email Literature Review of Ativan trials Research Report on Ativan
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Computational Assessment of GABA Receptor Modulation in PTSD Lorazepam 1 mg tablet, Placebo tablet - Stress Disorders, Post-Traumatic | Phase 4 | Recruiting | VA Office of Research and Development | 150 | 2025-07-01 | 2026-06-16 |
| Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression Lorazepam, Placebo - Depression, Anxiety, Fear | Phase 4 | Recruiting | Laureate Institute for Brain Research, Inc. | 165 | 2023-11-08 | 2025-10-31 |
| Evaluating Sublingual Dexmedetomidine For Moderate To Severe Agitation In Inpatients With Schizophrenia Or Bipolar Disorder Dexmedetomidine, Lorazepam 2 MG/ML - Schizophrenia Agitation, Schizo Affective Disorder | Phase 4 | Unknown | Temple University | 32 | 2023-07-01 | 2023-10-23 |
| Multimodal Analgesia Effect on Post Surgical Patient Neurontin, Dilaudid Injectable Product, Marcaine Injectable Product - Obesity, Morbid, Surgery | Phase 4 | Completed | University of California, Davis | 60 | 2021-01-20 | 2026-09-14 |
| Phenobarbital vs Ativan for Alcohol Withdrawal in the Intensive Care Unit Phenobarbital, Lorazepam - Alcohol Withdrawal, Alcohol Withdrawal Delirium | Phase 4 | Unknown | OSF Healthcare System | 142 | 2020-07-06 | 2020-10-08 |
| Multi-modal Assessment of Gamma-aminobutyric Acid (GABA) Function in Psychosis Placebo and fMRI, Lorazepam and fMRI - Schizophrenia, Bipolar Disorder | Phase 4 | Completed | University of Michigan | 143 | 2020-01-16 | 2026-06-17 |
| Alcohol Withdrawal Syndrome Treated With Adjunctive Phenobarbital or Ketamine Ketamine, Phenobarbital, Lorazepam - Alcohol Withdrawal Syndrome | Phase 4 | Withdrawn | Santa Barbara Cottage Hospital | 2019-04-12 | 2019-09-19 | |
| Oral Sedation During Cervical Dilator Placement Oxycodone and Lorazepam (Active Comparator), Placebo Comparator - Oral Sedation and Cervical Dilator Pain | Phase 4 | Completed | Johns Hopkins University | 27 | 2017-06-28 | 2020-03-30 |
| A Multi-level Life-span Characterization of Adult-depression and Effects of Medication and Exercise Venlafaxine XR, Aerobic Exercise, Lorazepam - Depression, Depressive Disorder, Major | Phase 4 | Completed | Kirk Erickson, PhD | 31 | 2015-03-01 | 2018-05-23 |
| Characterizing and Predicting Drug Effects on Cognition Lorazepam, Placebo, Topiramate 100mg - Cognitive Deficits | Phase 4 | Completed | University of Minnesota | 60 | 2013-07-01 | 2019-12-17 |
| Treatment of Alcohol Withdrawal in Hospital Patients Lorazepam (drug), Lorazepam - Alcohol Withdrawal Syndrome | Phase 4 | Completed | Virginia Commonwealth University | 183 | 2001-04-01 | 2016-04-11 |
Bipolar Disorder (2) · Depression (2) · Psychotic Disorders (2) · Schizophrenia (2) · Agnosia (1) · Alcohol Withdrawal Delirium (1) · Anxiety Disorders (1) · Cognition Disorders (1) · Depressive Disorder (1) · Depressive Disorder, Major (1) · Motor Activity (1) · Obesity, Morbid (1) · Psychomotor Agitation (1) · Stress Disorders, Post-Traumatic (1)
Johns Hopkins University (1) · Kirk Erickson, PhD (1) · Laureate Institute for Brain Research, Inc. (1) · OSF Healthcare System (1) · Santa Barbara Cottage Hospital (1) · Temple University (1) · University of California, Davis (1) · University of Michigan (1) · University of Minnesota (1) · VA Office of Research and Development (1) · Virginia Commonwealth University (1)
United States (10)
Barbara Jachniewicz, MSN, CRNFA, (1) · Bhagat Aulakh, MD (1) · Carolyn Sufrin (1) · Jessica K Lee, MD (1) · Jonathan R Howlett, MD (1) · Kirk Erickson, PhD (1) · Maria Ironside, DPhil (1) · Michael F. Weaver, MD (1) · Mohamed R Ali, MD, FACS (1) · Noah Stites-Hallet, MD (1) · Stephan Taylor, MD (1) · Susan E. Marino, PhD (1)
PMID 16785215, PMID 30797651, PMID 32297992
K23AA000222 (1), R01MH118634 (1), R01MH132565 (1)