9 recruiting, 5 completed, 2 unknown, 1 active not recruiting. 6 Not applicable, 5 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Recruiting 3, Completed 2, Unknown 1 |
| Phase 2 | 5 | Recruiting 3, Active not recruiting 1, Unknown 1 |
| Phase 1 | 3 | Recruiting 2, Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Vulva Cancer: new trials by email Literature Review of Vulva Cancer trials Research Report on Vulva Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pembrolizumab Plus Lenvatinib in Vulvar Cancer Patients: MITO VULVA-01 Pembrolizumab, Lenvatinib Capsules - Vulva Cancer | Phase 2 | Recruiting | National Cancer Institute, Naples | 80 | 2026-03-12 | 2026-04-02 |
| SLN Mapping and ICG Dye for Vulvar Cancer Indocyanine green - Vulva Cancer | Not yet recruiting | Tufts Medical Center | 10 | 2025-11-01 | 2025-09-29 | |
| Simulation Supported Vulva Cancer and Self-Examination on Knowledge, Skills and Attitude Simulation-Based Vulvar Cancer and Self-Vulvar Examination Training - Vulva Cancer, Nurse Role | Not applicable | Completed | Trakya University | 94 | 2025-05-08 | 2025-09-12 |
| Carbon Nanoparticle-Loaded Iron in the Treatment of Advanced Solid Tumor Carbon Nanoparticle-Loaded Iron [CNSI-Fe], Carbon Nanoparticle-Loaded Iron - Tumor, Solid, Lung Cancer | Phase 1 / Phase 2 | Recruiting | Sichuan Enray Pharmaceutical Sciences Company | 54 | 2024-11-12 | 2026-02-25 |
| Danish Vulva Cancer Recurrence Study Measurement of circulating tumor-DNA, Collection of patient-reported outcomes, Algorithmically determined telephone interview with a nurse - Vulva Cancer, Vulva Neoplasm | Not applicable | Recruiting | University of Aarhus | 1295 | 2024-08-15 | 2026-04-29 |
| 3D Printed Custom Applicators for HDR BT (DISCO) 3D-printed custom applicator - Gynecologic Cancer, Endometrial Cancer | Not applicable | Recruiting | Royal North Shore Hospital | 10 | 2023-11-24 | 2026-02-06 |
| SCG142 TCR-T Cells for Human Papillomavirus-Associated Carcinomas SCG142 TCR-T cells - Human Papillomavirus Associated Carcinomas, Cervical Cancer | Phase 1 | Recruiting | The Affiliated Hospital of Qingdao University | 18 | 2023-08-02 | 2024-08-09 |
| A Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Sequencing Methods on Liquid Biopsy Analysis (POPCORN) Solid Tumor, Advanced Solid Tumor | Recruiting | Centro di Riferimento Oncologico - Aviano | 782 | 2023-05-26 | 2023-09-13 | |
| ECT STUDY High-grade or Initially Invasive Vulva - GinOnc-ECT Study Bleomicina - Paget Disease of the Vulva, Vulva Cancer | Phase 2 | Active not recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 18 | 2023-05-23 | 2025-08-08 |
| Optical Guided Sentinel Node Biopsy for Staging of Vulvar Cancer Vulva Cancer, Sentinel Lymph Node | Recruiting | Copenhagen University Hospital, Rigshospitalet | 100 | 2023-05-01 | 2023-12-13 | |
| Neo-adjuvant Pembrolizumab in Vulvar Squamous Cell Carcinoma: a Clinical Proof-of-concept Study Pembrolizumab - Vulva Cancer, Vulva Neoplasm | Phase 2 | Unknown | Leiden University Medical Center | 40 | 2023-04-01 | 2023-03-09 |
| E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers E7 TCR-T cells, Aldesleukin - Cervical Cancer, Throat Cancer | Phase 2 | Recruiting | Christian Hinrichs | 20 | 2023-03-07 | 2026-06-12 |
| A Safety and Efficacy Study of Intra-tumoural Diffusing Alpha Radiation Emitters for the Treatment of Vulva Cancer DaRT Diffusing Alpha-emitters Radiation Therapy - Vulva Cancer, Recurrent, Vulvar Squamous Cell Carcinoma | Not applicable | Unknown | CCTU- Cancer Theme | 10 | 2023-02-28 | 2023-05-25 |
| Prolonged Grief and Perception of Femininity in Gynecological Cancer Patients Such as art therapy, play therapy, breathing techniques - Cervix Cancer, Uterine Cancer | Not applicable | Completed | Kevser Pamuk | 80 | 2023-02-26 | 2024-02-01 |
| Carbon Nanoparticle-Loaded Iron [CNSI-Fe(II)] in the Treatment of Advanced Solid Tumor CNSI-Fe(II) 30 mg, CNSI-Fe(II) 60 mg, CNSI-Fe(II) 90 mg - Advanced Solid Tumor, Lung Cancer | Phase 1 | Completed | Sichuan Enray Pharmaceutical Sciences Company | 19 | 2022-11-17 | 2025-08-03 |
| Sentinel Node Extended in Squamous Cell Vulvar Cancer Sentinel node biopsy - Vulva Cancer, Sentinel Lymph Node | Completed | Diana Zach | 64 | 2019-12-14 | 2023-11-01 | |
| Fluorescence for Sentinel Lymph Node Identification in Cancer Surgery Indocyanine green, Technetium99, Optonuclear probe - Breast Carcinoma, Head and Neck Cancer | Phase 3 | Completed | Institut de Cancérologie de Lorraine | 744 | 2017-11-29 | 2026-09-01 |
| Prospective Biobanking Study in Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE) Tumor biopsies / Tumor surgery, Blood withdrawal - Ovarian Cancer, Triple-Negative Breast Cancer | Not applicable | Recruiting | Institut Curie | 1050 | 2017-01-06 | 2026-02-03 |
Vulvar Neoplasms (18) · Uterine Cervical Neoplasms (8) · Ovarian Neoplasms (5) · Endometrial Neoplasms (4) · Anus Neoplasms (3) · Breast Neoplasms (3) · Head and Neck Neoplasms (3) · Pancreatic Neoplasms (3) · Vaginal Neoplasms (3) · Colorectal Neoplasms (2) · Lung Neoplasms (2) · Melanoma (2) · Neoplasms (2) · Penile Neoplasms (2) · Thyroid Neoplasms (2)
Female Urogenital Diseases (18) · Female Urogenital Diseases and Pregnancy Complications (18) · Genital Diseases (18) · Genital Diseases, Female (18) · Genital Neoplasms, Female (18) · Neoplasms by Site (18) · Urogenital Diseases (18) · Urogenital Neoplasms (18) · Vulvar Diseases (17) · Neoplasms (16) · Uterine Diseases (9) · Uterine Cervical Diseases (8) · Uterine Neoplasms (8) · Digestive System Diseases (6) · Digestive System Neoplasms (6)
Indocyanine Green (2) · pembrolizumab (2) · Adoptive Transfer (1) · Art Therapy (1) · Bleomycin (1) · Cisplatin (1) · Infracyanine green (1) · Play Therapy (1) · Sentinel Lymph Node Biopsy (1) · Technetium-99 (1) · aldesleukin (1) · lenvatinib (1) · nanocis (1)
Sichuan Enray Pharmaceutical Sciences Company (2) · CCTU- Cancer Theme (1) · Centro di Riferimento Oncologico - Aviano (1) · Christian Hinrichs (1) · Copenhagen University Hospital, Rigshospitalet (1) · Diana Zach (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Institut Curie (1) · Institut de Cancérologie de Lorraine (1) · Kevser Pamuk (1) · Leiden University Medical Center (1) · National Cancer Institute, Naples (1) · Royal North Shore Hospital (1) · The Affiliated Hospital of Qingdao University (1) · Trakya University (1)
China (3) · Italy (3) · Denmark (2) · France (2) · Turkey (Türkiye) (2) · United States (2) · Australia (1) · Sweden (1) · United Kingdom (1)
Aysel Karaca (1) · Christian S Hinrichs, MD (1) · Diana Zach, MD (1) · Fabio Puglisi, MD, PhD (1) · Giacomo Corrado (1) · Jeremy Booth, PhD QMP (1) · Li Tee Tan (1) · Marita Morgia, MD (1) · Pernille T. Jensen, Professor (1) · Rafael Gonzalez, MD (1) · Sandro Pignata, MD, PhD (1) · Yongsheng Wang, PhD & MD (1)
PMID 28744123, PMID 29186019, PMID 30184767, PMID 31796533, PMID 32510916, PMID 34766118, PMID 35418195, PMID 37918956, PMID 38909994, PMID 39612700, PMID 42249319, PMID 42816483
2019 (1), 2023 (1), U01CA287904 (1)