51 completed, 21 recruiting, 19 unknown, 8 active not recruiting. 59 Not applicable, 24 Phase 2, 9 Phase 1, 9 Phase 3, 3 Early Phase 1.
Follow Sentinel Lymph Node Biopsy: new trials by email Literature Review of Sentinel Lymph Node Biopsy trials Research Report on Sentinel Lymph Node Biopsy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Zanubrutinib and Sonrotoclax for the Treatment of Relapsed Chronic Lymphocytic Leukemia /Small Lymphocytic Leukemia, ZeuS-2 Trial Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | Phase 2 | Not yet recruiting | City of Hope Medical Center | 44 | 2027-08-04 | 2026-09-10 |
| A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information Biospecimen Collection, Chest Radiography, Computed Tomography - Clinical Stage 0 Cutaneous Melanoma AJCC v8, Clinical Stage I Cutaneous Melanoma AJCC v8 | Phase 2 | Recruiting | Children's Oncology Group | 51 | 2027-05-15 | 2026-09-24 |
| Feasibility and Effectiveness of Sentinel Lymph Node Biopsy in Inflammatory Breast Cancer Sentinel node biopsy with blue dye and radioisotope - Breast Cancer | Not applicable | Not yet recruiting | Case Comprehensive Cancer Center | 20 | 2027-01-01 | 2026-10-21 |
| NAUTILUS-04: No Axillary Surgical Treatment in Low-Risk Clinically Node-Negative Breast Cancer Without Whole-Breast Radiotherapy Omission of axillary surgery, Sentinel lymph node biopsy - Breast Cancer (Early Breast Cancer), Sentinel Lymph Node Biopsy | Not applicable | Not yet recruiting | Wonshik Han | 1520 | 2026-10-01 | 2026-10-08 |
| Hotspot Stereotactic Ablative Radiotherapy Versus Traditional Stereotactic Ablative Radiotherapy for the Treatment of Early-Stage Non-Small Cell Lung Cancer Biospecimen Collection, Computed Tomography, Lymph Node Biopsy - Early Stage Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8 | Phase 2 | Recruiting | Roswell Park Cancer Institute | 200 | 2026-09-01 | 2026-08-26 |
| A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS) Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Rhabdomyosarcoma | Phase 3 | Recruiting | Children's Oncology Group | 342 | 2026-07-14 | 2026-08-25 |
| Axillary Web Syndrome After Breast Cancer Surgery: Incidence, Risk Factors, and Functional Outcomes Axillary surgery (sentinel lymph node biopsy or axillary lymph node dissection) - Axillary Web Syndrome, Breast Cancer | Recruiting | Antalya City Hospital | 250 | 2026-05-01 | 2026-08-21 | |
| Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma Adjuvant Therapy, Comprehensive Geriatric Assessment, Computed Tomography - Cutaneous Melanoma | Phase 3 | Recruiting | ECOG-ACRIN Cancer Research Group | 428 | 2026-04-17 | 2026-09-24 |
| Patent Blue SLN in Early Ovarian Cancer Prospective Study (FIGO I-II) Evaluating Patent Blue SLN Mapping. Injection Into IP/UO Ligaments in Situ. Goals: Assess Feasibility and Accuracy vs Standard Lymphadenectomy to Minimize Surgical Morbidity Sentinel node biopsy with patent blue dye - Sentinel Lymph Node Biopsy (SLNB), Early Stage Ovarian Tumors | Recruiting | Faculty of Medicine of Tunis | 30 | 2026-04-15 | 2026-09-10 | |
| De-escalating Axillary Surgery in Breast Cancer Patients in Nigeria Sentinel lymph Node Biopsy - Breast Cancer, Axilla; Breast | Not applicable | Not yet recruiting | Nova Scotia Health Authority | 100 | 2025-11-01 | 2024-08-22 |
| De-escalation in Axillary Surgery for Early-stage Breast Cancer sentinel lymph node biopsy, omission of sentinel lymph node biopsy - Omitting Sentinel Lymph Node Biopsy in Early-stage Breast Cancer | Not applicable | Not yet recruiting | Clinical Hospital Center Rijeka | 620 | 2025-09-10 | 2025-08-01 |
| Sarcoidosis Immunotsuppressive Therapy and Lymphoma Development lymph node biopsy - Sarcoidosis Lung | Completed | Alexandria University | 40 | 2025-08-01 | 2026-01-15 | |
| International Prospective Multicentre Study That Evaluate the Sentinel Lymph Node Detection Rate in Patients With First Local Recurrent Scamous Cell Carcinoma of the Vulva. Sentinel Lymph Node Biopsy in first local recurrent vulvar carcinoma - Recurent Vulvar Carcinoma | Not applicable | Enrolling by invitation | Hospital Universitario La Paz | 100 | 2025-08-01 | 2025-06-17 |
| Personalized Neck Radiation Therapy Directed by Sentinel Lymph Node Biopsy for the Treatment of Oral Cavity Squamous Cell Carcinoma, PRECEDENT Trial Biospecimen Collection, Carboplatin, Cisplatin - Oral Cavity Squamous Cell Carcinoma, Stage I Lip and Oral Cavity Cancer AJCC v8 | Phase 2 | Recruiting | University of Michigan Rogel Cancer Center | 50 | 2025-07-17 | 2026-07-31 |
| Phase 2 Pragmatic Trial of Sentinel Lymph Node Biopsy (SLNB) in Patients With Clinically Node-Negative (cN0), High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) of the Head and Neck Sentinel lymph node biopsy (SLNB), Lymphadenectomy, Adjuvant Definitive Therapy - Cutaneous Squamous Cell Carcinoma of the Head and Neck, Clinically Node-Negative (cN0) | Phase 2 | Withdrawn | University of California, Davis | 2025-06-25 | 2026-08-31 | |
| Implementation of Indocyanine Green to Identify Sentinel Lymph Nodes During Surgery for Breast Cancer Technetium (99mTc), Indocyanine Green, Sentinel lymph node biopsy - Breast Cancer, Sentinel Lymph Node Biopsy (SLNB) | Not applicable | Recruiting | Isabelle Henskens | 1760 | 2025-04-18 | 2026-06-25 |
| Sentinel Node Biopsy Versus Limited Elective Neck Dissection in Early Cancers of Oral Cavity NoDe Negative Sentinel Node Biopsy, Limited Elective Neck Dissection - Mouth Neoplasms, Oral Cancers | Not applicable | Recruiting | Tata Memorial Hospital | 508 | 2025-04-16 | 2025-07-17 |
| Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advanced or Metastatic Pancreatic Cancer Biopsy, Biospecimen Collection, Computed Tomography - Locally Advanced Pancreatic Adenocarcinoma, Metastatic Pancreatic Adenocarcinoma | Phase 2 | Active not recruiting | Mayo Clinic | 24 | 2024-12-06 | 2026-06-18 |
| To Evaluate the Effectiveness and Safety of Single-port Robotic-assisted Subcutaneous Gland Resection Combined With Immediate Breast Reconstruction in Breast Cancer sentinel lymph node biopsy, Single-port robotic-assisted axillary lymph node dissection - Breast Cancer | Not applicable | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 40 | 2024-12-01 | 2024-11-29 |
| Implementation of Surgical Safety and Intraoperative Metastasis Identification Through Deep Learning: Multicentric Video Collection for Minimally Invasive Sentinel Lymph Node Dissection in Uterine Malignancies Sentinel lymph node sampling - Endometrial Cancer, Cervical Cancer | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 100 | 2024-09-17 | 2024-10-02 |
Showing 20 of 121. Sign in to see all of them.
Breast Neoplasms (48) · Melanoma (11) · Uterine Cervical Neoplasms (10) · Endometrial Neoplasms (9) · Mouth Neoplasms (6) · Squamous Cell Carcinoma of Head and Neck (5) · Carcinoma, Intraductal, Noninfiltrating (4) · Leukemia, Lymphocytic, Chronic, B-Cell (3) · Rectal Neoplasms (3) · Triple Negative Breast Neoplasms (3) · Vulvar Neoplasms (3) · Anus Neoplasms (2) · Breast Carcinoma In Situ (2) · Breast Neoplasms, Male (2) · Colonic Neoplasms (2)
M.D. Anderson Cancer Center (6) · Roswell Park Cancer Institute (4) · Alliance for Clinical Trials in Oncology (3) · Gangnam Severance Hospital (3) · National Cancer Institute (NCI) (3) · Washington University School of Medicine (3) · Case Comprehensive Cancer Center (2) · Cedars-Sinai Medical Center (2) · Centre hospitalier de l'Université de Montréal (CHUM) (2) · Children's Oncology Group (2) · Dana-Farber Cancer Institute (2) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (2) · Istanbul University (2) · Memorial Sloan Kettering Cancer Center (2) · Peking University People's Hospital (2)
United States (53) · China (10) · Canada (7) · France (5) · Italy (5) · Turkey (Türkiye) (5) · South Korea (4) · Australia (3) · Brazil (3) · Egypt (3) · Netherlands (3) · Czechia (2) · India (2) · Russia (2) · Spain (2)
Clinton Yam (2) · Erwei Song, M.D., Ph.D. (2) · Jean-Francois Rodier, MD (2) · Aiping Shi, Doctor (1) · Alex Mlynarek, MD (1) · Alice Chung, MD (1) · Amy Cyr, M.D. (1) · Andrea Barrio, MD (1) · Andrew Birkeland, MD (1) · Andrew G Renehan (1) · Annemiek Doeksen, MD, PhD (1) · Armando E. Giuliano, MD (1) · Armando Giuliano, MD (1) · Bence Dorogi, MD (1)
PMID 11192930, PMID 12356141, PMID 14965682, PMID 15166963, PMID 15614159, PMID 16164916, PMID 16192820, PMID 16514477, PMID 16677594, PMID 16740298, PMID 17330838, PMID 17485709, PMID 18723148, PMID 18777194, PMID 20142602, PMID 20195151, PMID 20309640, PMID 21489874, PMID 21569373, PMID 21791687, PMID 21918427, PMID 22308288, PMID 22366409, PMID 22868365, PMID 24101169, PMID 25175452, PMID 25452445, PMID 25646192, PMID 25664534, PMID 25777085, PMID 26047592, PMID 27214241, PMID 28657941, PMID 29980907, PMID 30640706, PMID 31203203, PMID 31796533, PMID 32043193, PMID 32750501, PMID 34253579, PMID 34763939, PMID 35507014, PMID 35914239, PMID 3652025, PMID 3663535, PMID 37132193, PMID 37505106, PMID 37547448, PMID 37918956, PMID 38345718
U10CA027469 (2), U10CA180868 (2), U10CA180886 (2), 2019 (1), P01CA084203 (1), P30CA014089 (1), P30CA016059 (1), P30CA016672 (1), P30CA022453 (1), P30CA033572 (1), P30CA093373 (1), R01CA120228 (1), U10CA180820 (1), UM1CA121947 (1)