9 unknown, 5 completed, 2 active not recruiting, 2 recruiting. 5 Phase 2, 2 Not applicable, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 2, Active not recruiting 1, Recruiting 1, Terminated 1 |
| Not applicable | 2 | Completed 1, Unknown 1 |
| Phase 1 | 2 | Completed 1, Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Safety and Efficacy Study of Intra-tumoural Diffusing Alpha Radiation Emitters for the Treatment of Vulva Cancer DaRT Diffusing Alpha-emitters Radiation Therapy - Vulva Cancer, Recurrent, Vulvar Squamous Cell Carcinoma | Not applicable | Unknown | CCTU- Cancer Theme | 10 | 2023-02-28 | 2023-05-25 |
| Perioperative Encobini in BRAFV600 Mutant Stage III (B/C/D) or Oligometastatic Stage IV Melanoma Encorafenib + Binimetinib, Standard Adjuvant Treatment - Melanoma, Cancer | Phase 2 | Active not recruiting | CCTU- Cancer Theme | 18 | 2023-02-27 | 2026-10-26 |
| Metabolic and Immunological Phenotyping in Patients With Cancer Observational assessments - Cancer, Non-Hematologic Malignancy | Unknown | CCTU- Cancer Theme | 80 | 2021-12-07 | 2024-02-02 | |
| Pre-operative Stereotactic Ablative Body Radiotherapy Followed by Immediate Surgery for Pancreatic Cancer Pre-operative stereotactic ablative body radiotherapy - Cancer of Pancreas | Not applicable | Completed | CCTU- Cancer Theme | 10 | 2020-10-26 | 2026-04-20 |
| WIRE - Novel Treatments in Renal Cell Cancer Olaparib, Cediranib, Volrustomig - Renal Cell Cancer | Phase 2 | Recruiting | CCTU- Cancer Theme | 134 | 2020-07-27 | 2026-09-25 |
| Microbiome Immunotherapy Toxicity and Response Evaluation Nivolumab, Pembrolizumab, Ipilimumab - Melanoma, Renal Cancer | Unknown | CCTU- Cancer Theme | 1800 | 2020-07-08 | 2023-02-16 | |
| A Study to Collect Bone Marrow for Process Development and Production of BM-MSC to Treat Severe COVID19 Pneumonitis Bone Marrow Harvest - Healthy Volunteers for Bone Marrow Donation | Unknown | CCTU- Cancer Theme | 10 | 2020-05-01 | 2020-05-21 | |
| Evaluation of Novel Diagnostic Tests for COVID-19 SAMBA II (Diagnostic for the Real World), Public Health England Gold Standard, Cambridge Validated Viral Detection Method - Acute Disease, Coronavirus | Unknown | CCTU- Cancer Theme | 200 | 2020-04-06 | 2020-05-18 | |
| Identification of Novel Biomarkers of Response to Systemic Treatments in Renal Cell Cancer Laboratory analysis of samples, Application of machine learning - Carcinoma, Renal Cell | Unknown | CCTU- Cancer Theme | 12 | 2020-01-01 | 2019-08-19 | |
| AZD6738 & Gemcitabine as Combination Therapy AZD6738, Gemcitabine - Cancer | Phase 1 | Unknown | CCTU- Cancer Theme | 55 | 2019-10-15 | 2021-06-04 |
| Heuristics, Algorithms and Machine Learning: Evaluation & Testing in Radiation Therapy Radical Image-Guided Radiotherapy - Cancer | Recruiting | CCTU- Cancer Theme | 310 | 2019-09-11 | 2021-08-02 | |
| Therapeutics in Active Prostate Cancer Surveillance Apalutamide - Prostate Cancer | Phase 2 | Completed | CCTU- Cancer Theme | 11 | 2018-06-05 | 2019-11-19 |
| Neo-RT: A Study Investigating Whether Changing the Sequence of Treatments (Starting Radiotherapy Followed by Hormone Therapy Before Surgery) is Feasible Intensity modulated radiotherapy (IMRT), Endocrine therapy, Breast conserving surgery - Breast Cancer | Active not recruiting | CCTU- Cancer Theme | 43 | 2018-03-26 | 2026-10-05 | |
| Predicting Sites of Tumour Progression in the Invasive Margin of Glioblastomas (PRaM-GBM Study) Diffusion tensor Imaging (DTI) - High Grade Glioma | Completed | CCTU- Cancer Theme | 147 | 2017-03-02 | 2024-09-27 | |
| To Assess the Safety of Continuous IV Administration of Plerixafor in Patients With Advanced Pancreatic, Ovarian and Colorectal Cancers Plerixafor - Pancreatic Adenocarcinoma Metastatic, Ovarian Serous Adenocarcinoma | Phase 1 | Completed | CCTU- Cancer Theme | 26 | 2015-06-01 | 2019-07-23 |
| LUCID - LUng Cancer CIrculating Tumour Dna Study Blood sampling, Surplus Tumour Tissue sample collection from surgery, Collection or archival tumour tissue (If available) - Non Small Cell Lung Cancer | Unknown | CCTU- Cancer Theme | 100 | 2015-01-01 | 2019-11-06 | |
| Cambridge Liquid Biopsy and Tumour Profiling Study for Patients on Experimental Therapeutics Trials Cancer | Unknown | CCTU- Cancer Theme | 100 | 2014-12-08 | 2019-07-22 | |
| Pancreatic Resectability in Cancers With Known Limited Extension (PRICKLE) Abraxane, Gemcitabine - Pancreatic Adenocarcinoma | Phase 2 | Terminated | CCTU- Cancer Theme | 9 | 2014-07-01 | 2019-07-16 |
| Scheduling Nab-paclitaxel With Gemcitabine Abraxane (nab-paclitaxel), Gemcitabine - Pancreatic Adenocarcinoma Metastatic | Phase 2 | Completed | CCTU- Cancer Theme | 146 | 2014-01-01 | 2019-07-16 |
Neoplasms (6) · Pancreatic Neoplasms (3) · Carcinoma, Renal Cell (2) · Melanoma (2) · Acute Disease (1) · Breast Neoplasms (1) · COVID-19 (1) · Carcinoma, Non-Small-Cell Lung (1) · Colorectal Neoplasms (1) · Coronavirus Infections (1) · Glioma (1) · Kidney Neoplasms (1) · Lung Neoplasms (1) · Neoplasm Metastasis (1) · Ovarian Neoplasms (1)
Gemcitabine (3) · 130-nm albumin-bound paclitaxel (2) · Albumin-Bound Paclitaxel (2) · Bevacizumab (1) · Blood Specimen Collection (1) · Diagnosis (1) · Diagnostic Imaging (1) · Diffusion Tensor Imaging (1) · Ipilimumab (1) · Mastectomy, Segmental (1) · Nivolumab (1) · Radiotherapy, Intensity-Modulated (1) · Tomography, X-Ray Computed (1) · apalutamide (1) · atezolizumab (1)
United Kingdom (18)
Pippa Corrie (3) · Amy Bates (1) · Andrew McCaskie, FRCS (1) · Brent O'Carrigan (1) · Bristi Basu, Dr (1) · Charlotte E Coles, MB ChB, MRCP, FRCR, PhD (1) · Claire Connell (1) · Duncan Jodrell (1) · Grant D Stewart (1) · Li Tee Tan (1) · Nitzan Rosenfeld, PhD (1) · Professor Duncan Jodrell (1) · Raj Dr. Jena (1) · Ravindra Prof. Gupta, BMBCh (1) · Richard Baird (1)
PMID 32350413, PMID 34794412, PMID 35073853, PMID 36813867, PMID 38981998, PMID 41369900
2014 (1), 2017 (1), 2019 (1)