7 completed, 4 recruiting, 2 unknown, 1 not yet recruiting. 6 Not applicable, 5 Phase 3, 4 Phase 2, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 5, Not yet recruiting 1 |
| Phase 3 | 5 | Completed 2, Unknown 2, Recruiting 1 |
| Phase 2 | 4 | Unknown 2, Recruiting 1, Terminated 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Vitamin C: new trials by email Literature Review of Vitamin C trials Research Report on Vitamin C
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dietary Supplements in Patients With Coronary Artery Bypass Grafting for Improving the Quality of Healthcare Delivery. Vitamin C, Omega 3 PUFA (EPO/DHA), Lignin, Lactulose - Cardio-pulmonary Bypass, Cardiovascular Diseases | Not applicable | Not yet recruiting | Nicosia General Hospital | 108 | 2026-09-01 | 2026-05-13 |
| Effect of Double Nutri® Liposomal Encapsulation Technology on Human Absorption of Vitamin C and Glutathione Liquid Sachet Vitamin C and Glutathione without liposome, Liposomal Vitamin C and Glutathione - Vitamin C, Glutathione | Not applicable | Completed | TCI Co., Ltd. | 20 | 2025-12-15 | 2026-02-03 |
| Effect of Vitamin C on Length of Hospital Stay in Children With Severe Pneumonia Antibiotics administration, Vitamin C - Pneumonia Childhood, Vitamin C | Phase 4 | Recruiting | Children's Hospital and Institute of Child Health, Multan | 90 | 2025-08-28 | 2026-02-17 |
| Gingival Hyperpigmentation Treatment Vitamin c and glutathione, Surgical depigmentation - Gingival Pigmentation, Depigmentation | Phase 2 | Recruiting | Cairo University | 30 | 2025-08-01 | 2026-05-19 |
| High - Dose Vitamin C Infusion Regimen Based on Pharmacokinetic Characteristics for Patients With Advanced Malignant Solid Tumors high - dose vitamin C - Vitamin C | Phase 1 | Recruiting | Zhongnan Hospital | 18 | 2025-03-30 | 2025-08-13 |
| Combination of IV Ascorbic Acid and Adebrelimab in Metastatic Colorectal Cancer Ascorbic acid, FOLFOX Protocol, Adebrelimab - Colorectal Cancer, Vitamin C | Phase 3 | Recruiting | Fudan University | 400 | 2024-12-01 | 2024-10-24 |
| Vitamin C on Acute and Chronic Post Mastectomy Pain vitamin C group, placebo group - Vitamin C, Post-mastectomy Pain Syndrome | Not applicable | Completed | Tanta University | 204 | 2023-04-01 | 2025-12-29 |
| Influence of High Vitamin C Dose on Lactate During and After Extracorporeal Circulation ascorbic acid,, Placebo (saline) - Hyperlactatemia, Cardiac Disease | Not applicable | Completed | University Medical Centre Maribor | 70 | 2023-03-01 | 2025-02-21 |
| Role of Vitamin C Infusion in Postoperative Mechanically Ventilated Neonates With Sepsis Placebo, Vitamin C - Vitamin C, Postoperative | Not applicable | Completed | Tanta University | 50 | 2023-02-01 | 2025-01-17 |
| Efficacy of Megadose Vitamin C in Severe and Critical Ill COVID-19 Patients. Vitamin C, Placebo - Vitamin C, COVID-19 Pneumonia | Phase 2 / Phase 3 | Unknown | Zhujiang Hospital | 608 | 2023-01-13 | 2023-01-23 |
| Lessening Organ Dysfunction With VITamin C - COVID-19 Vitamin C, Control - Vitamin C, COVID-19 | Phase 3 | Completed | Université de Sherbrooke | 392 | 2020-08-14 | 2023-04-21 |
| Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia VC, Sterile Water for Injection - Vitamin C, Pneumonia, Viral | Phase 2 | Terminated | ZhiYong Peng | 56 | 2020-02-14 | 2020-10-12 |
| Oral Vitamin C Administration on Erythropoietin Dosing Requirement in End-Stage Renal Disease Patients on Regular Hemodialysis Normal regimen of treatment of anemia, Vitamin C - Vitamin C, Oral Administration | Not applicable | Completed | Ain Shams University | 60 | 2019-08-01 | 2025-12-18 |
| Lessening Organ Dysfunction With VITamin C Vitamin C, Control - Sepsis, Vitamin C | Phase 3 | Completed | Université de Sherbrooke | 872 | 2018-11-08 | 2022-04-04 |
| Role of Vitamin C to Augment Iron Chelation With DFP or DFX Vitamin C, Defriprone, deferisarox, deferiprone , deferesarox - Vitamin c, Thalassemia Major | Phase 2 / Phase 3 | Unknown | Ain Shams University | 50 | 2014-04-01 | 2014-03-11 |
COVID-19 (3) · Coronavirus Infections (2) · Sepsis (2) · Cardiovascular Diseases (1) · Colorectal Neoplasms (1) · Heart Diseases (1) · Heart Valve Diseases (1) · Hyperlactatemia (1) · Kidney Failure, Chronic (1) · Neoplasms (1) · Pneumonia (1) · Pneumonia, Ventilator-Associated (1) · Pneumonia, Viral (1) · Vitiligo (1) · beta-Thalassemia (1)
Infections (6) · Lung Diseases (5) · Pathological Conditions, Signs and Symptoms (5) · Respiratory Tract Diseases (5) · Respiratory Tract Infections (5) · Pathologic Processes (4) · Pneumonia (4) · Virus Diseases (4) · Coronaviridae Infections (3) · Nidovirales Infections (3) · Pneumonia, Viral (3) · RNA Virus Infections (3) · Disease Attributes (2) · Inflammation (2) · Systemic Inflammatory Response Syndrome (2)
Ascorbic Acid (13) · Glutathione (2) · Deferiprone (1) · Folfox protocol (1) · Injections (1) · Isoflurophate (1) · Lactulose (1) · Lignin (1) · Liposomes (1) · Sodium Chloride (1)
Ain Shams University (2) · Tanta University (2) · Université de Sherbrooke (2) · Cairo University (1) · Children's Hospital and Institute of Child Health, Multan (1) · Fudan University (1) · Nicosia General Hospital (1) · TCI Co., Ltd. (1) · University Medical Centre Maribor (1) · ZhiYong Peng (1) · Zhongnan Hospital (1) · Zhujiang Hospital (1)
Egypt (5) · China (4) · Canada (2) · Cyprus (1) · Pakistan (1) · Slovenia (1) · Taiwan (1)
Athanasios D. Athanasiou, MD, MSc, MPA (1) · Ayesha F Assitant Professor, FCPS (1) · Elpidoforos S. Soteriades, MD, Ass Prof (1) · Guoxiang Cai, Doctor (1) · Liu Zhanguo, MD,PhD (1) · Neill Adhikari, MDCM FRCPC MSc (1) · Neill K Adhikari, MDCM, FRCPC, MSc (1) · Nourhan A Abdullah, Phd (1) · Tong-Lin Wu (1) · Zhiyong Peng, professor (1)
PMID 31915072, PMID 32641343, PMID 34020705, PMID 35704292, PMID 37877585, PMID 39774855, PMID 40927646, PMID 41315087