70 completed, 34 unknown, 21 recruiting, 13 terminated. 65 Not applicable, 35 Phase 2, 10 Phase 1, 7 Phase 3, 5 Early Phase 1.
Follow Vestibulocochlear Nerve Diseases: new trials by email Literature Review of Vestibulocochlear Nerve Diseases trials Research Report on Vestibulocochlear Nerve Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Role of ChatGPT in Vestibular Schwannoma Management Use of chatGPT for 1 week - Vestibular Schwannoma | Not applicable | Withdrawn | University of Southern California | 2027-01-01 | 2026-01-13 | |
| Luvometinib in Combination With Serplulimab for NF2-Related Tumors Luvometinib, Serplulimab - NF2-related Schwannomatosis, NF2 | Phase 1 / Phase 2 | Not yet recruiting | Beijing Tiantan Hospital | 30 | 2026-07-31 | 2026-07-16 |
| Platform Research for Innovative Medicines in NF2-SWN (PRIME-NF2) Selumetinib 25mg/m2, Luvometinib, Serplulimab - Neurofibromatosis Type 2, Vestibular Schwannoma | Phase 2 | Not yet recruiting | Beijing Tiantan Hospital | 200 | 2026-07-18 | 2026-07-20 |
| Selumetinib for NF2-Related Schwannomatosis Selumetinib - Neurofibromatosis Type 2, NF2 | Phase 2 | Not yet recruiting | Beijing Tiantan Hospital | 20 | 2026-07-15 | 2026-07-16 |
| Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures Panitumumab-IRDye800 - Meningioma, Glioblastoma | Early Phase 1 | Recruiting | Eben Rosenthal | 30 | 2026-07-07 | 2026-10-16 |
| Study to Determine Optimal Dose, Evaluate the Efficacy and Safety of PRG-N-01 in Patients With Neurofibromatosis Type II Trineumin - Neurofibromatosis Type II, NF2 | Phase 1 / Phase 2 | Not yet recruiting | PRG Science & Technology Co., Ltd. | 25 | 2026-07-01 | 2026-01-23 |
| Measuring Vestibular Organ Function With Weak Alternating Current Stimulation Active transcranial electrical vestibular stimulation (Active EVS), Sham transcranial electrical vestibular stimulation (Sham EVS), Control measurement - Vestibular Disorder, Vestibular Schwannoma | Not applicable | Enrolling by invitation | Aalto University | 30 | 2026-06-08 | 2026-07-01 |
| Oliceridine Versus Sufentanil for Postoperative Nausea in Cerebellopontine Angle Surgery Oliceridine, Sufentanil - PONV, Cerebellopontine Angle Tumor | Not applicable | Recruiting | Xuanwu Hospital, Beijing | 174 | 2026-03-25 | 2026-05-22 |
| Long Term Follow-up Study of AAVAnc80-antiVEGF Gene Therapy Vestibular Schwannoma | Enrolling by invitation | Akouos, Inc. | 100 | 2026-03-02 | 2026-07-16 | |
| Assessment of Patient Experience With Auto-Captioning Glasses in NF2-Related-Schwannomatosis Auto-captioning Glasses - NF2-related Schwannomatosis | Not applicable | Completed | Massachusetts General Hospital | 18 | 2026-02-19 | 2026-08-25 |
| 3D MRE-Based Evaluation of Vestibular Schwannoma Mechanical Properties and Histological Features Vestibular Schwannoma | Recruiting | Shengjing Hospital | 30 | 2025-09-25 | 2026-10-16 | |
| Vestibular Rehabilitation Protocol in Unilateral Vestibular Schwannoma No Intervention: Observational Cohort, Structured home-based vestibular telerehabilitation program, CE-marked clinical rotatory chair - Vestibular Schwannoma, Vestibular Schwannomas | Not applicable | Recruiting | Albert Torrents Torrero | 75 | 2025-09-01 | 2026-01-23 |
| Steroids for Facial Nerve Function Protection in Post-surgical Vestibular Schwannoma Patients Steroids therapy, Placebo - Vestibular Schwannoma, Facial Nerve Paralysis | Phase 3 | Not yet recruiting | Beijing Tiantan Hospital | 364 | 2025-09-01 | 2025-08-12 |
| Quantitative Eye Movement Measurements in Patients with Acute Vestibular Syndrome video-oculography - Acute Vestibular Syndrome, Vertigo | Not applicable | Not yet recruiting | Alexander Tarnutzer | 75 | 2025-07-01 | 2024-10-31 |
| Mapping of Vestibular Centers Activation Using fMRI in Patients With Vestibular Schwannoma vestibular schwannoma resection - Vestibular Schwannoma, Unilateral Vestibular Deficit | Not applicable | Recruiting | Marketa Bonaventurova | 40 | 2025-06-01 | 2026-10-22 |
| Early Rehabilitation Using Head Impulse Test for Acute Vestibular Deficit Experimental treatment: Head movements, Sham treatment: only eye movements - Vestibular Schwannoma, Unilateral Vestibular Deficit | Not applicable | Recruiting | Hospices Civils de Lyon | 26 | 2025-05-13 | 2025-05-16 |
| Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma AAVAnc80-antiVEGF via Akouos Delivery Device - Vestibular Schwannoma | Phase 1 / Phase 2 | Recruiting | Akouos, Inc. | 27 | 2025-01-17 | 2026-04-06 |
| Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent RVP-001 - Central Nervous System (CNS) Lesions, Brain Metastases | Phase 2 | Completed | Reveal Pharmaceuticals Inc. | 18 | 2024-08-15 | 2025-12-26 |
| Effect of Peripheral Vestibular Disease Location on Outcomes Following Home-based Virtual Reality Vestibular Therapy Standard Vestibular Rehabilitation with Adjunct At Home Virtual Reality Vestibular Rehabilitation, Standard Vestibular Rehabilitation with Adjunct Auditory Intervention - Peripheral Vestibular Disorder, Benign Paroxysmal Positional Vertigo | Not applicable | Unknown | University of British Columbia | 50 | 2024-06-01 | 2024-08-15 |
| USPIO Enhanced MR Imaging in CNS Tumours (UMIC) USPIO enhanced MRI - Vestibular Schwannoma, Glioma, Astrocytic | Not applicable | Recruiting | Northern Care Alliance NHS Foundation Trust | 17 | 2024-04-26 | 2024-08-27 |
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Neuroma, Acoustic (98) · Neurofibromatosis 2 (47) · Vestibular Neuronitis (33) · Meningioma (18) · Dizziness (13) · Vertigo (11) · Vestibular Diseases (11) · Brain Neoplasms (10) · Ependymoma (10) · Hearing Loss (8) · Neurilemmoma (8) · Neurofibromatoses (8) · Neurofibromatosis 1 (7) · Meniere Disease (6)
Cranial Nerve Diseases (162) · Nervous System Diseases (161) · Ear Diseases (160) · Retrocochlear Diseases (160) · Otorhinolaryngologic Diseases (159) · Cranial Nerve Neoplasms (122) · Neoplasms by Histologic Type (122) · Neoplasms, Nerve Tissue (122) · Nerve Sheath Neoplasms (122) · Neuroectodermal Tumors (122) · Neuroendocrine Tumors (122) · Otorhinolaryngologic Neoplasms (122) · Neoplasms, Germ Cell and Embryonal (121) · Neuroma (121)
Bevacizumab (7) · Radiosurgery (6) · Cochlear Implants (4) · Everolimus (4) · AZD 6244 (3) · Gentamicins (3) · Adrenal Cortex Hormones (2) · Ginkgo Extract (2) · HDAC-42 (2) · Lapatinib (2) · Methylprednisolone (2) · Prednisone (2) · Sirolimus (2) · ((3-methoxythiophen-2-yl)methyl)((2-(9-(pyridin-2-yl)-6-oxaspiro(4.5)decan-9-yl)ethyl))amine (1) · 2,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide (1)
Massachusetts Eye and Ear Infirmary (6) · Massachusetts General Hospital (6) · Beijing Tiantan Hospital (5) · NYU Langone Health (5) · University Hospital, Strasbourg, France (4) · Johns Hopkins University (3) · Lund University (3) · Medical University of Vienna (3) · University Hospital Tuebingen (3) · University of Alabama at Birmingham (3) · Aalborg University Hospital (2) · Akouos, Inc. (2) · Assistance Publique - Hôpitaux de Paris (2) · Assistance Publique Hopitaux De Marseille (2) · Central Hospital, Nancy, France (2)
United States (69) · France (19) · China (9) · United Kingdom (9) · Austria (5) · Canada (4) · Germany (4) · Norway (4) · Sweden (4) · Denmark (3) · Czechia (2) · Israel (2) · Italy (2) · Netherlands (2) · South Korea (2)
Ana-Maria Vranceanu, PhD (3) · Matthias A Karajannis, MD, MS (3) · Aaron Tward, MD (2) · D. Bradley Welling, MD, PhD (2) · Fu Zhao (2) · Matthew L Carlson, MD (2) · Pinan Liu (2) · Scott Plotkin, MD (2) · Theodore Nicolaides, MD (2) · Alexander A Tarnutzer, MD (1) · Andrea Giacobbo, PT (1) · Anhua Wu, MD (1) · Anna Bedenko, PhD student (1)
PMID 17917842, PMID 19574236, PMID 19645909, PMID 22027076, PMID 10449559, PMID 11587600, PMID 11710496, PMID 11981398, PMID 12925338, PMID 12943357, PMID 14724495, PMID 15269315, PMID 15354006, PMID 15519876, PMID 15979939, PMID 17141563, PMID 17438254, PMID 17562049, PMID 17905655, PMID 18607963, PMID 18769654, PMID 19464947, PMID 19645932, PMID 20517167, PMID 20541460, PMID 20592851, PMID 20592852, PMID 20647135, PMID 20709596, PMID 20802221, PMID 20851113, PMID 21586257, PMID 21993052, PMID 23123220, PMID 23333609, PMID 23573135, PMID 23673615, PMID 24604142, PMID 24904885, PMID 25745609, PMID 26055840, PMID 26247776, PMID 26490109, PMID 26943915, PMID 26976425, PMID 28053986, PMID 28391531, PMID 28439223, PMID 28520834, PMID 28811848
2017 (1), P30CA006973 (1), P30CA008748 (1), P30CA086862 (1), R01DC003196 (1), R01DC012593 (1), R01DC017425 (1), R44CA261240 (1), U01CA069856 (1), U01DC013778 (1)