11 completed, 2 terminated, 2 unknown, 1 active not recruiting. 16 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 16 | Completed 11, Terminated 2, Unknown 2, Active not recruiting 1 |
Follow Vestibular Diseases: new trials by email Literature Review of Vestibular Diseases trials Research Report on Vestibular Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SPI-1005 for the Treatment of Meniere's Disease (Open Label) Ebselen - Meniere's Disease, Ménière's Disease | Phase 3 | Active not recruiting | Sound Pharmaceuticals, Incorporated | 200 | 2025-10-29 | 2026-07-13 |
| Efficacy and Safety of Intravenous Diazepam Given at 2 Different Doses Compared to Placebo in Acute Peripheral Vertigo Diazepam 5mg, Diazepam 10 mg, Placebo - Vertigo, Peripheral | Phase 3 | Unknown | University of Monastir | 1000 | 2024-05-01 | 2024-04-02 |
| SPI-1005 for the Treatment of Meniere's Disease Ebselen, Placebo - Meniere Disease, Ménière | Phase 3 | Completed | Sound Pharmaceuticals, Incorporated | 220 | 2022-08-02 | 2026-07-23 |
| Comparison of Efficacy of Metoclopramide , Promethazine and Prochloroperazine in the Treatment of Vertigo. Metoclopramid ( 10mg), IM promethazine (25mg) , IM prochloroperazine( 12.5mg) - Peripheral Vertigo | Phase 3 | Unknown | Oman Medical Speciality Board | 90 | 2022-02-01 | 2024-12-16 |
| Efficacy and Safety of Buspirone, Sustained-release Tablets, 15 mg in Patients With Autonomic Dysfunction Syndrome Accompanied by Vertigo Buspirone, Placebo - Vertigo, Autonomic Dysfunction | Phase 3 | Completed | Valenta Pharm JSC | 268 | 2022-01-28 | 2022-06-24 |
| Phase 3 Study of OTO-104 in Subjects With Unilateral Meniere's Disease OTO-104, Placebo - Meniere Disease | Phase 3 | Completed | Otonomy, Inc. | 148 | 2018-08-27 | 2022-12-07 |
| Non Inferiority of Meclin® (Meclizine Chlorhydrate) Versus Dramin® (Dimenhydrinate) in Control of Acute Vertigo Symptoms From Peripheral Origin Meclizine, Dimenhydrinate - Vertigo, Peripheral | Phase 3 | Completed | Apsen Farmaceutica S.A. | 292 | 2016-11-01 | 2026-09-08 |
| Study of OTO-104 in Subjects With Unilateral Meniere's Disease OTO-104, Placebo - Meniere's Disease | Phase 3 | Terminated | Otonomy, Inc. | 176 | 2016-03-21 | 2023-01-13 |
| Study of OTO-104 in Subjects With Unilateral Meniere's Disease OTO-104, Placebo - Meniere's Disease | Phase 3 | Completed | Otonomy, Inc. | 166 | 2015-10-27 | 2023-01-12 |
| The Efficacy of Steroid Therapy in Vestibular Neuritis Ginkgo biloba & Methylprednisolone, Ginkgo biloba - Vestibular Neuritis | Phase 3 | Completed | Asan Medical Center | 40 | 2014-03-01 | 2019-01-10 |
| Promethazine vs. Lorazepam for Treatment of Vertigo Promethazine, Lorazepam - Peripheral Vertigo. | Phase 3 | Completed | Shahid Beheshti University of Medical Sciences | 210 | 2013-04-01 | 2013-06-14 |
| The Treatment of Posterior Semicircular Canal Benign Paroxysmal Positional Vertigo Modified Epley maneuver, Semont maneuver, Reverse Epley maneuver - Benign Paroxysmal Positional Vertigo | Phase 3 | Completed | Asan Medical Center | 99 | 2012-10-01 | 2014-01-08 |
| Famvir for Treatment of Hearing in Unilateral Meniere's Disease Famciclovir, Placebo - Meniere's Disease | Phase 3 | Terminated | House Research Institute | 11 | 2011-12-01 | 2021-04-19 |
| Treatment of Apogeotropic Horizontal Canal Benign Paroxysmal Positional Vertigo Gufoni maneuver, Head-shaking maneuver, sham maneuver - HC-BPPV | Phase 3 | Completed | Chonbuk National University | 157 | 2009-01-01 | 2011-06-27 |
| Treatment of Geotropic Horizontal Canal Benign Paroxysmal Positional Vertigo Gufoni, Sham, Barbecue - Benign Paroxysmal Positional Vertigo | Phase 3 | Completed | Chonbuk National University | 170 | 2009-01-01 | 2011-06-06 |
| Canalith Repositioning Procedure for BPPV in Primary Care Canalith repositioning maneuver (CRM) - Benign Paroxysmal Positional Vertigo | Phase 3 | Completed | McMaster University | 56 | 2002-01-01 | 2024-03-15 |
Vertigo (13) · Meniere Disease (6) · Benign Paroxysmal Positional Vertigo (4) · Dizziness (3) · Hearing Loss (3) · Tinnitus (3) · Nystagmus, Pathologic (2) · Otorhinolaryngologic Diseases (2) · Ear Diseases (1) · Endolymphatic Hydrops (1) · Labyrinth Diseases (1) · Primary Dysautonomias (1) · Vestibular Neuronitis (1)
Nervous System Diseases (16) · Neurologic Manifestations (16) · Pathological Conditions, Signs and Symptoms (16) · Signs and Symptoms (16) · Ear Diseases (15) · Labyrinth Diseases (15) · Otorhinolaryngologic Diseases (14) · Endolymphatic Hydrops (5) · Sensation Disorders (4) · Cranial Nerve Diseases (3) · Hearing Disorders (3) · Vertigo (3) · Eye Diseases (2) · Ocular Motility Disorders (2)
ebselen (2) · Buspirone (1) · Diazepam (1) · Dimenhydrinate (1) · Famciclovir (1) · Ginkgo Extract (1) · Lorazepam (1) · Meclizine (1) · Methylprednisolone (1) · Promethazine (1) · salicylhydroxamic acid (1)
Otonomy, Inc. (3) · Asan Medical Center (2) · Chonbuk National University (2) · Sound Pharmaceuticals, Incorporated (2) · Apsen Farmaceutica S.A. (1) · House Research Institute (1) · McMaster University (1) · Oman Medical Speciality Board (1) · Shahid Beheshti University of Medical Sciences (1) · University of Monastir (1) · Valenta Pharm JSC (1)
United States (5) · South Korea (4) · Belgium (1) · Brazil (1) · Canada (1) · Germany (1) · Iran (1) · Italy (1) · Oman (1) · Poland (1) · Russia (1) · Spain (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Kathie Bishop, PhD (2) · Asma Al Buraiki, MD (1) · Hong Ju Park, Professor (1) · Hongju Park, Professor (1) · Jennifer Derebery, MD (1) · Juan Munoz, MD (1) · Norton Sayeg, PhD (1)