31 completed, 13 unknown, 6 recruiting, 6 terminated. 33 Not applicable, 11 Phase 4, 3 Phase 3, 2 Early Phase 1, 2 Phase 2.
Follow Urge Incontinence: new trials by email Literature Review of Urge Incontinence trials Research Report on Urge Incontinence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fluoroscopy Radiation Reduction During Sacral Neuromodulation Lead Placement Reduced radiation fluoroscopy, Conventional fluoroscopy - Radiation Exposure, Overactive Bladder | Not applicable | Recruiting | Loma Linda University | 44 | 2026-06-01 | 2026-03-06 |
| A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections Pro-Nox Nitrous Oxide/Oxygen Delivery System, Standard Care for Bladder Botox Injection, Sham Mask - Overactive Bladder, Neurogenic Bladder | Phase 4 | Not yet recruiting | TriHealth Inc. | 96 | 2026-02-01 | 2026-02-04 |
| Low-intensity Shockwave Therapy Versus Solifenacin for the Treatment of Overactive Bladder in Women Low intensity shockwave therapy, Oral Solifenacin succinate 5 mg - Overactive Bladder (OAB), Urge Incontinence | Phase 4 | Recruiting | Mansoura University | 70 | 2025-11-11 | 2026-03-16 |
| Assessing the Genitourinary Microbiome of Women With Overactive Bladder Undergoing Onabotulinum Toxin Type A Intradetrusor Injections onabotulinum toxin type a - Overactive Bladder (OAB), Urge Incontinence | Recruiting | Alexis Dieter | 40 | 2025-09-03 | 2025-09-12 | |
| Optimal Intravesical Lidocaine Volume for Pain Relief During Office Intra-detrusor Onabotulinum Toxin a Injections Lidocaine 2% without vessel constrictor - Overactive Bladder, Overactive Bladder Syndrome | Phase 4 | Not yet recruiting | University of Louisville | 36 | 2024-12-01 | 2024-11-19 |
| Prevalence, Types and Risk Factors of Urinary Incontinence Among Women in Baghdad, Iraq. Urinary Incontinence, Urge Incontinence | Unknown | Al-Kindy College of Medicine | 384 | 2024-03-01 | 2024-04-08 | |
| rTMS in Overactive Bladder Transcranial Magnetic Stimulation - Overactive Bladder, Overactive Bladder Syndrome | Not applicable | Completed | The Methodist Hospital Research Institute | 14 | 2024-01-08 | 2026-03-24 |
| Percutaneous Nerve Evaluation Trial Time Sacral neuromodulation - Urge Incontinence, Urgency-frequency Syndrome | Not applicable | Recruiting | University of Chicago | 193 | 2023-12-10 | 2026-02-09 |
| UCon Treatment of Overactive Bladder (OAB) in Males Urge stimulation, Time limited stimulation - Urinary Incontinence, Urge Incontinence | Not applicable | Recruiting | InnoCon Medical | 20 | 2023-10-12 | 2026-11-06 |
| Effect of Diaphragmatic Training on Urgency Urinary Incontinence in Postmenopausal Women anti muscarinic drugs, Instructions including bladder training, pelvic floor muscle training (PFMT) - Urge Incontinence, Urinary Incontinence | Not applicable | Completed | Cairo University | 60 | 2023-07-01 | 2024-07-25 |
| Effectiveness of eCoin at Sensory and Subsensory Amplitudes eCoin Peripheral Neurostimulator System - Urge Incontinence | Not applicable | Completed | Valencia Technologies Corporation | 38 | 2023-06-06 | 2025-11-03 |
| Lidocaine Patches Prior to Percutaneous Nerve Evaluation Lidocaine patch, Placebo - Overactive Bladder, Urge Incontinence | Phase 2 | Completed | University of Louisville | 39 | 2023-05-01 | 2025-02-03 |
| Social Media Navigation Aid Kits for Urinary Incontinence Social Media Navigation Aid Kit - Urinary Incontinence, Stress Incontinence, Female | Not applicable | Completed | University of New Mexico | 75 | 2023-04-24 | 2025-01-16 |
| A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE) eCoin Tibial Nerve Stimulation - Overactive Bladder, Urge Incontinence | Not applicable | Recruiting | Valencia Technologies Corporation | 200 | 2023-01-26 | 2026-10-19 |
| Prophylactic Antibiotic Administration for Bladder OnabotulinumtoxinA Injection Single-Dose Antibiotic, Multi-Dose Antibiotic - Overactive Bladder, Overactive Bladder Syndrome | Phase 4 | Completed | The Cleveland Clinic | 100 | 2022-12-06 | 2024-01-02 |
| AURA-2: Augmenting Urinary Reflex Activity Amber UI System - Overactive Bladder, Urge Incontinence | Not applicable | Completed | Amber Therapeutics Ltd | 13 | 2022-11-30 | 2024-08-12 |
| The Effect of Local Anesthetic Solution in the Bladder Prior to Botox Injections in the Bladder Alkalinized Lidocaine, Placebo Sodium Chloride 0.9% Inj - Urge Incontinence, Overactive Bladder | Phase 3 | Unknown | Herlev and Gentofte Hospital | 50 | 2022-09-12 | 2022-09-22 |
| Intradetrusor Botulinum Toxin A for OAB Via 1 Versus 10 Injections: A Randomized Clinical Trial OnabotulinumtoxinA 100 UNT [Botox] - Overactive Bladder, Urinary Urge Incontinence | Phase 4 | Completed | University of California, Irvine | 116 | 2022-05-01 | 2026-02-25 |
| A Sham-Controlled Study to Evaluate the Safety and Efficacy of a Smart, Self-Adjusting, Surgery-Free, Wearable Bladder Neuromodulation System for Overactive Bladder Avation System, Sham Avation System - Overactive Bladder, Urinary Urge Incontinence | Not applicable | Terminated | Avation Medical, Inc. | 125 | 2022-04-14 | 2024-05-29 |
| AURA 1: Augmenting Urinary Reflex Activity: Study 1 Picostim Amber - Overactive Bladder, Urge Incontinence | Not applicable | Withdrawn | Amber Therapeutics Ltd | 2022-04-01 | 2023-02-02 |
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Urinary Incontinence, Urge (62) · Urinary Bladder, Overactive (39) · Urinary Incontinence (19) · Urinary Incontinence, Stress (10) · Fecal Incontinence (4) · Nocturia (4) · Urinary Bladder, Neurogenic (4) · Pelvic Floor Disorders (3) · Lower Urinary Tract Symptoms (2) · Nocturnal Enuresis (2) · Pelvic Organ Prolapse (2) · Urinary Retention (2) · Agnosia (1) · Chronic Pain (1) · Diarrhea (1)
Female Urogenital Diseases (62) · Female Urogenital Diseases and Pregnancy Complications (62) · Male Urogenital Diseases (62) · Pathological Conditions, Signs and Symptoms (62) · Signs and Symptoms (62) · Urination Disorders (62) · Urogenital Diseases (62) · Urological Manifestations (62) · Urologic Diseases (61) · Lower Urinary Tract Symptoms (60) · Urinary Incontinence (43) · Urinary Bladder Diseases (39) · Neurologic Manifestations (7) · Nervous System Diseases (5) · Digestive System Diseases (4)
Botulinum Toxins, Type A (4) · Lidocaine (3) · Solifenacin Succinate (3) · Transcranial Magnetic Stimulation (2) · Transcutaneous Electric Nerve Stimulation (2) · mirabegron (2) · AIEOP acute lymphoblastic leukemia protocol (1) · Anti-Bacterial Agents (1) · Antibiotic Prophylaxis (1) · Dimethyl Sulfoxide (1) · Electric Stimulation Therapy (1) · Injections (1) · Nitrous Oxide (1) · Oxygen (1) · Phenazopyridine (1)
Valencia Technologies Corporation (4) · Amber Therapeutics Ltd (2) · Boston Urogynecology Associates (2) · InnoCon Medical (2) · Loma Linda University (2) · The Methodist Hospital Research Institute (2) · University of California, Irvine (2) · University of California, San Francisco (2) · University of Louisville (2) · University of Southern California (2) · Al-Kindy College of Medicine (1) · Alexis Dieter (1) · Alza Corporation, DE, USA (1) · Astellas Pharma China, Inc. (1) · Astellas Pharma Inc (1)
United States (37) · Belgium (4) · Denmark (3) · Spain (3) · Turkey (Türkiye) (3) · Brazil (2) · Egypt (2) · Netherlands (2) · Poland (2) · Australia (1) · China (1) · Czechia (1) · France (1) · Hungary (1) · Iraq (1)
Aftab Ahmed Mirza Baig, DPT, MSAPT (1) · Alison Huang, MS, MAS, MPhil (1) · Amy D. Dobberfuhl, M.D. (1) · Annemarie B Villadsen (1) · Carly Crowder, MD (1) · David Sheyn, MD (1) · Dr. Muhammad Hammad Mithani, MBBS, FCPS (1) · Dr. Syed Imran Ahmed, MBBS, FCPS (1) · Emily Slopnick, MD (1) · Felicia Lane, MD (1) · Forrest Jellison, MD (1) · Gloria Kolb, M.S. (1)
PMID 34156506, PMID 35167358, PMID 35536667, PMID 35580634, PMID 35607890, PMID 35622269, PMID 37160401, PMID 37811598, PMID 37930265, PMID 38540138, PMID 39033475, PMID 39186785, PMID 39621424, PMID 39797697, PMID 40013530, PMID 40025238, PMID 41359336, PMID 41420462, PMID 42311071, PMID 42348866, PMID 42781031
R01DK116712 (1)