3 recruiting. 3 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Recruiting 3 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Tuberous Sclerosis: new trials by email Literature Review of Tuberous Sclerosis trials Research Report on Tuberous Sclerosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety, Tolerability, and Pharmacokinetics of SVG103 (Paxalisib) in Focal Cortical Dysplasia Type II (FCD-II), Tuberous Sclerosis Complex (TSC) or Hemimegalencephaly (HME) SVG103 - Focal Cortical Dysplasia, Tuberous Sclerosis Complex (TSC) | Phase 1 / Phase 2 | Recruiting | Sovargen | 12 | 2026-07-14 | 2026-08-10 |
| Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders Sertraline, Placebo - Neurodevelopmental Disorders, Autism | Phase 2 | Recruiting | Holland Bloorview Kids Rehabilitation Hospital | 130 | 2024-09-16 | 2026-07-27 |
| Efficacy and Safety of Rapamycin Versus Vigabatrin in the Prevention of Tuberous Sclerosis Complex Symptoms in Infants Vigabatrin, Rapamycin, Placebo - Tuberous Sclerosis Complex | Phase 2 / Phase 3 | Recruiting | Katarzyna Kotulska | 60 | 2021-05-07 | 2026-10-22 |
22q11 Deletion Syndrome (1) · Anxiety Disorders (1) · Attention Deficit Disorder with Hyperactivity (1) · Autism Spectrum Disorder (1) · Autistic Disorder (1) · DiGeorge Syndrome (1) · Epilepsy (1) · Focal Cortical Dysplasia (1) · Fragile X Syndrome (1) · Hemimegalencephaly (1) · Neoplasms (1) · Neurodevelopmental Disorders (1) · Tic Disorders (1) · Tourette Syndrome (1)
Congenital Abnormalities (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Hamartoma (3) · Heredodegenerative Disorders, Nervous System (3) · Malformations of Cortical Development (3) · Malformations of Cortical Development, Group I (3) · Neoplasms, Multiple Primary (3) · Neoplastic Syndromes, Hereditary (3) · Nervous System Diseases (3) · Nervous System Malformations (3) · Neurocutaneous Syndromes (3) · Neurodegenerative Diseases (3) · Brain Diseases (2) · Central Nervous System Diseases (2)
Fluid Therapy (1) · Selective Serotonin Reuptake Inhibitors (1) · Sertraline (1) · Sirolimus (1) · Vigabatrin (1)
Holland Bloorview Kids Rehabilitation Hospital (1) · Katarzyna Kotulska (1) · Sovargen (1)
Australia (1) · Canada (1) · Poland (1)