2 recruiting, 1 withdrawn. 1 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1 | Withdrawn 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Hemimegalencephaly: new trials by email Literature Review of Hemimegalencephaly trials Research Report on Hemimegalencephaly
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety, Tolerability, and Pharmacokinetics of SVG103 (Paxalisib) in Focal Cortical Dysplasia Type II (FCD-II), Tuberous Sclerosis Complex (TSC) or Hemimegalencephaly (HME) SVG103 - Focal Cortical Dysplasia, Tuberous Sclerosis Complex (TSC) | Phase 1 / Phase 2 | Recruiting | Sovargen | 12 | 2026-07-14 | 2026-08-10 |
| Use of a Tonometer to Identify Epileptogenic Lesions During Pediatric Epilepsy Surgery Intra-operative brain tonometry - Epilepsy, Focal Cortical Dysplasia | Not applicable | Withdrawn | University of California, Los Angeles | 2018-07-16 | 2023-10-10 | |
| Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies Sampling of blood, frozen resected tissues, and cerebrospinal fluid (CSF) - Drug-resistant Focal Epilepsies in Pediatric Population | Recruiting | Fondation Ophtalmologique Adolphe de Rothschild | 450 | 2015-12-17 | 2026-04-17 |
Focal Cortical Dysplasia (3) · Tuberous Sclerosis (3) · Encephalitis (2) · Brain Neoplasms (1) · Epilepsies, Partial (1) · Epilepsy (1) · Gliosis (1) · Hypothalamic hamartomas (1) · Polymicrogyria (1) · Stroke (1) · Sturge-Weber Syndrome (1)
Congenital Abnormalities (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Craniofacial Abnormalities (3) · Genetic Diseases, Inborn (3) · Hamartoma (3) · Heredodegenerative Disorders, Nervous System (3) · Malformations of Cortical Development (3) · Malformations of Cortical Development, Group I (3) · Megalencephaly (3) · Musculoskeletal Abnormalities (3) · Musculoskeletal Diseases (3) · Neoplasms (3) · Neoplasms, Multiple Primary (3) · Neoplastic Syndromes, Hereditary (3) · Nervous System Diseases (3)
Fondation Ophtalmologique Adolphe de Rothschild (1) · Sovargen (1) · University of California, Los Angeles (1)
Australia (1) · Canada (1) · France (1) · United States (1)
Aria Fallah, MD (1)
PMID 31444548, PMID 33407896, PMID 33434304, PMID 33834539, PMID 36307217, PMID 37324239, PMID 38710875, PMID 39460693, PMID 40307383