11 completed, 3 recruiting, 1 not yet recruiting. 12 Not applicable, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Completed 9, Recruiting 2, Not yet recruiting 1 |
| Early Phase 1 | 1 | Completed 1 |
Follow Thermoregulation: new trials by email Literature Review of Thermoregulation trials Research Report on Thermoregulation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AI-Guided Predictions of Blood Pressure Dysregulation Using Perfusion Index as a Novel Biomarker in Persons With Spinal Cord Injury Controlled Cool Thermal Challenge (18°C) - Spinal Cord Injuries (SCI), Blood Pressure | Not applicable | Recruiting | James J. Peters Veterans Affairs Medical Center | 24 | 2026-09-01 | 2026-08-10 |
| Effect of Thermoregulation Bundle Applied at Birth on Neonatal Physiological Parameters and Breastfeeding Thermoregulation bundle, routine care - Thermoregulation, Neonatal Hypothermia | Not applicable | Recruiting | Istanbul University - Cerrahpasa | 140 | 2025-11-01 | 2026-05-05 |
| The Effects of Caffeine on Exercise Physiology and Time-trial Performance in a Hot Environment Hot environment, Thermoneutral environment - Caffeine, Thermoregulation | Not applicable | Not yet recruiting | St. Mary's University, Twickenham | 15 | 2025-08-22 | 2025-08-19 |
| Identifying the Limits of Survivability in Heat-exposed Older Females Humidity-Ramp Protocol, Above-inflection fixed-condition exposure (5%), Below-inflection fixed-condition exposure (5%) - Heat Stress, Temperature Change, Body | Not applicable | Completed | University of Ottawa | 12 | 2025-07-16 | 2026-06-11 |
| Physiological Responses to Heat Stress During High-risk Events None-placebo - Thermoregulation | Recruiting | United States Army Research Institute of Environmental Medicine | 150 | 2025-05-31 | 2026-05-05 | |
| Enhancing Heat Resiliency in Older Adults During Indoor Overheating Via Heat Acclimation by Warm Water Immersion Heat acclimation by warm-water immersion - Hyperthermia, Thermoregulation | Not applicable | Completed | University of Ottawa | 16 | 2024-11-11 | 2026-06-11 |
| Effect of Pre-cooling on Whole-body Heat Loss During Exercise-heat Stress No Cooling, Pre-Cooling - Thermoregulation, Cold Exposure | Not applicable | Completed | University of Ottawa | 10 | 2024-10-24 | 2025-06-17 |
| Does Mirabegron Increase the Body Heat Generated by the Nervous System Myrbetriq 25Mg Extended-Release Tablet, Placebo - Thermoregulation | Early Phase 1 | Completed | Christopher Bell | 19 | 2023-04-27 | 2024-06-06 |
| Acute Sleep Deprivation on Whole-body Heat Exchange During Exercise-heat Stress in Young and Older Men Sleep deprivation, Normal sleep - Thermoregulation, Sleep Disturbance | Not applicable | Completed | University of Ottawa | 21 | 2022-12-01 | 2024-07-15 |
| Hot Water Immersion as a Heat Acclimation Strategy in Older Adults Heat acclimation - Hyperthermia, Heat Exposure | Not applicable | Completed | University of Ottawa | 12 | 2022-04-29 | 2024-07-11 |
| Assessment of Vasomotion of People With Idiopathic Chilblains Assessment of Vasomotion of People With Idiopathic Chilblains - Chilblains, Perniosis | Not applicable | Completed | University of Thessaly | 16 | 2022-03-15 | 2024-03-25 |
| Delaying First Bathing and Skin Barrier Function on Infant Bathing - Premature, Thermoregulation | Not applicable | Completed | Akdeniz University | 80 | 2020-02-20 | 2022-10-03 |
| Cooling Fabrics and Exercise Performance in Endurance Athletes Cooling Fabric, Placebo Garment - Cooling Fabrics, Exercise Performance | Not applicable | Completed | McGill University | 20 | 2014-01-01 | 2015-08-26 |
| Impact of Active Thermoregulation on the Microcirculation of Free Flaps Hilotherm Clinic® - Microcirculation, Thermoregulation | Not applicable | Completed | Ulf Dornseifer, MD | 25 | 2013-11-01 | 2015-07-07 |
| Management and Thermal Comfort of Premature Infants Under 32 Weeks mesure of skin temperature - Thermoregulation | Completed | Centre Hospitalier Universitaire, Amiens | 29 | 2010-06-04 | 2026-06-16 |
Heat Stress Disorders (6) · Motor Activity (3) · Hyperthermia (2) · Body Temperature Changes (1) · Chilblains (1) · Parasomnias (1) · Premature Birth (1) · Spinal Cord Injuries (1)
Wounds and Injuries (8) · Behavior (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Body Temperature Changes (2) · Nervous System Diseases (2) · Central Nervous System Diseases (1) · Cold Injury (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Frostbite (1) · Mental Disorders (1) · Obstetric Labor Complications (1) · Obstetric Labor, Premature (1) · Pregnancy Complications (1) · Sleep Wake Disorders (1)
Baths (1) · mirabegron (1)
University of Ottawa (5) · Akdeniz University (1) · Centre Hospitalier Universitaire, Amiens (1) · Christopher Bell (1) · Istanbul University - Cerrahpasa (1) · James J. Peters Veterans Affairs Medical Center (1) · McGill University (1) · St. Mary's University, Twickenham (1) · Ulf Dornseifer, MD (1) · United States Army Research Institute of Environmental Medicine (1) · University of Thessaly (1)
Canada (6) · United States (3) · Turkey (Türkiye) (2) · France (1) · Germany (1) · Greece (1)
Glen P Kenny, PhD (3) · Andreas Flouris, PhD (1) · Christopher Bell, Ph.D. (1) · Dennis Jensen, Ph.D. (1) · Glen P Kenny, PhD. (1) · Pierre Tourneux, PU-PH (1) · Ulf Dornseifer, MD (1)
PMID 33210328, PMID 39491044, PMID 39820413, PMID 40623158, PMID 41549363, PMID 42406578