10 completed, 3 not yet recruiting, 2 unknown, 1 recruiting. 6 Not applicable, 3 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 5, Unknown 1 |
| Phase 4 | 3 | Not yet recruiting 2, Unknown 1 |
Follow Cold Injury: new trials by email Literature Review of Cold Injury trials Research Report on Cold Injury
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis | Phase 4 | Not yet recruiting | Jay C. Buckey Jr. | 100 | 2026-11-01 | 2026-09-09 |
| Field Study on Intravenous Iloprost for Treatment of Severe Frostbite at High Altitude Iloprost (Ilomedin, BAYQ6256) - Frostbite, Altitude | Not yet recruiting | Institute of Mountain Emergency Medicine | 10 | 2026-05-01 | 2026-03-09 | |
| Epoprostenol Plus Conventional Therapy in COld and Frostbite Injury (ECCO) Standard of care plus Epoprostenol infusion for 8 hours (hrs) per day up to 5 days maximum, Standard of Care + Placebo (Normal Saline)infusion for 8 hours per day up to 5 days maximum - Frostbite | Phase 4 | Not yet recruiting | University of Colorado, Denver | 66 | 2026-02-01 | 2026-02-20 |
| Prevention and Treatment of Frostbite Infection With Antimicrobial Pharmacokinetic Analysis Long-Acting silver dressings, Aloe Vera, Dalbavancin - Frostbite | Phase 4 | Unknown | University of Colorado, Denver | 100 | 2024-03-01 | 2024-05-13 |
| Comparison of ICG Microangiography and Conventional Angiography in Severe Frostbite Indocyanine Green Angiogram - Frostbite | Completed | HealthPartners Institute | 8 | 2023-02-03 | 2026-07-30 | |
| Multicenter Sous Vide Frostbite Sous Vide Device (SVD) - Frostbite, Frostbite of Hand | Not applicable | Completed | Dartmouth-Hitchcock Medical Center | 7 | 2022-12-01 | 2025-12-30 |
| Assessment of Vasomotion of People With Idiopathic Chilblains Assessment of Vasomotion of People With Idiopathic Chilblains - Chilblains, Perniosis | Not applicable | Completed | University of Thessaly | 16 | 2022-03-15 | 2024-03-25 |
| Sous Vide Rewarming for Frostbitten Extremities Sous Vide Device (SVD) - Frostbite, Frostbite of Hand | Not applicable | Completed | Dartmouth-Hitchcock Medical Center | 1 | 2021-01-14 | 2021-09-28 |
| Cutaneous Manifestations of Coronavirus Disease 2019(COVID-19). Cutaneous Manifestations, Skin Manifestations | Completed | Jinnah Postgraduate Medical Centre | 1206 | 2020-07-31 | 2021-11-22 | |
| COVID-19 and Chilblains Biological sample collection - Chilblains, COVID-19 | Not applicable | Completed | Rennes University Hospital | 269 | 2020-07-21 | 2025-01-08 |
| Analysis of Chilblains pROfile During coVID-19 Epidemic (ACROVID) Biological Sample Collection - COVID-19, Chilblains | Not applicable | Completed | Poitiers University Hospital | 11 | 2020-04-30 | 2021-11-29 |
| Assessment of Chilbains Occuring During Covid-19 Infection Skin Manifestations, COVID | Recruiting | Centre Hospitalier Universitaire de Nice | 30 | 2020-04-09 | 2026-06-29 | |
| Acral Cutaneous Thrombotic Vasculopathy and Covid-19 Infection COVID 19 | Completed | University Hospital, Montpellier | 10 | 2020-04-01 | 2020-12-29 | |
| Characteristics and the Future of the City Chilblains Chilblains | Completed | Fondation Hôpital Saint-Joseph | 50 | 2016-02-01 | 2017-04-05 | |
| 10-years Nationwide Alpine Accidents in Austria general and specific data - Alpine Accident, Frostbite | Completed | Medical University Innsbruck | 500 | 2015-01-21 | 2018-01-23 | |
| CAERvest® - A Novel Endothermic Hypothermic Device for Core Body Cooling. Safety and Efficacy Testing. Cooling - Hypothermia. | Not applicable | Unknown | Bodychillz Ltd | 30 | 2014-03-01 | 2014-03-04 |
Frostbite (9) · Chilblains (7) · COVID-19 (4) · Skin Manifestations (2) · Vasculitis (2) · Calciphylaxis (1) · Candidiasis, Oral (1) · Colitis, Ulcerative (1) · Coronavirus Infections (1) · Craniocerebral Trauma (1) · Crohn Disease (1) · Enterocolitis, Pseudomembranous (1) · Epidermolysis Bullosa (1) · Erythema Multiforme (1) · Graft vs Host Disease (1)
Wounds and Injuries (16) · Frostbite (7) · Infections (5) · Cardiovascular Diseases (4) · Coronaviridae Infections (4) · Lung Diseases (4) · Nidovirales Infections (4) · Pathological Conditions, Signs and Symptoms (4) · Pneumonia (4) · Pneumonia, Viral (4) · RNA Virus Infections (4) · Respiratory Tract Diseases (4) · Respiratory Tract Infections (4) · Signs and Symptoms (4)
Cool-Down Exercise (1) · Histidine-tRNA Ligase (1) · Iloprost (1) · Oxygen (1) · Standard of Care (1) · dalbavancin (1)
Dartmouth-Hitchcock Medical Center (2) · University of Colorado, Denver (2) · Bodychillz Ltd (1) · Centre Hospitalier Universitaire de Nice (1) · Fondation Hôpital Saint-Joseph (1) · HealthPartners Institute (1) · Institute of Mountain Emergency Medicine (1) · Jay C. Buckey Jr. (1) · Jinnah Postgraduate Medical Centre (1) · Medical University Innsbruck (1) · Poitiers University Hospital (1) · Rennes University Hospital (1) · University Hospital, Montpellier (1) · University of Thessaly (1)
France (5) · United States (5) · Austria (1) · Greece (1) · Italy (1) · Pakistan (1) · United Kingdom (1)
Nicholas Daniel, DO (2) · Alexandra Lacey, MD (1) · Andreas Flouris, PhD (1) · Arek J Wiktor, MD, FACS (1) · Arek Wiktor, MD (1) · Jay Buckey (1) · Peter Paal, Dr (1) · Rabia Ghafoor, MBBS, FCPS, SCE-Derm(MRCP-UK) (1) · Rowland L Cottingham, FRCS FCEM (1) · Syeda Mahanum Ali, MBBS, Postgraduate Trainee (1)