2 completed, 1 terminated. 3 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 2, Terminated 1 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
Follow Systemic Mastocytosis: new trials by email Literature Review of Systemic Mastocytosis trials Research Report on Systemic Mastocytosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Flotetuzumab for the Treatment of Relapsed or Refractory Advanced CD123-Positive Hematological Malignancies Acetaminophen, Dexamethasone, Diphenhydramine - Recurrent Acute Leukemia, Recurrent B Acute Lymphoblastic Leukemia | Phase 1 | Completed | City of Hope Medical Center | 13 | 2020-11-18 | 2026-01-28 |
| GTB-3550 Tri-Specific Killer Engager (TriKE®) for High Risk Hematological Malignancies GTB-3550 TriKE® Phase I, GTB-3550 TriKE® Phase II - High-risk Myelodysplastic Syndromes, Acute Myelogenous Leukemia | Phase 1 / Phase 2 | Terminated | GT Biopharma, Inc. | 12 | 2020-01-01 | 2022-11-10 |
| A Study of Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Hematologic Malignancies Nilotinib - Chronic Myelogenous Leukemia, Acute Lymphoblastic Leukemia (Philadelphia Chromosome Positive) | Phase 1 / Phase 2 | Completed | Novartis Pharmaceuticals | 507 | 2005-04-01 | 2021-06-29 |
Mastocytosis, Systemic (3) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (2) · Blastic Plasmacytoid Dendritic Cell Neoplasm (1) · Burkitt Lymphoma (1) · Hematologic Neoplasms (1) · Hodgkin Disease (1) · Hypereosinophilic Syndrome (1) · Leukemia, Hairy Cell (1) · Leukemia, Mast-Cell (1) · Leukemia, Myeloid, Acute (1) · Myelodysplastic Syndromes (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (1)
Bone Marrow Diseases (3) · Hematologic Diseases (3) · Hemic and Lymphatic Diseases (3) · Immune System Diseases (3) · Leukemia (3) · Leukemia, Myeloid (3) · Mast Cell Activation Disorders (3) · Mastocytosis (3) · Neoplasms (3) · Neoplasms by Histologic Type (3) · Neoplasms, Connective Tissue (3) · Neoplasms, Connective and Soft Tissue (3) · Chronic Disease (2) · Disease Attributes (2) · Immunoproliferative Disorders (2)
Acetaminophen (1) · Calcium Dobesilate (1) · Dexamethasone (1) · Diphenhydramine (1) · Ibuprofen (1) · Ranitidine (1) · auricularum (1) · dexamethasone 21-phosphate (1) · dexamethasone acetate (1) · nilotinib (1)
City of Hope Medical Center (1) · GT Biopharma, Inc. (1) · Novartis Pharmaceuticals (1)
United States (3) · Australia (1) · Austria (1) · Belgium (1) · Canada (1) · Denmark (1) · Finland (1) · France (1) · Germany (1) · Hong Kong (1) · Italy (1) · Netherlands (1) · New Zealand (1) · Norway (1) · Poland (1)
Ibrahim T Aldoss (1) · Mark B Juckett, MD (1)
PMID 16775235, PMID 17715389, PMID 21098399, PMID 23547655, PMID 24057647, PMID 26002753, PMID 35622074
P30CA033572 (1)