19 completed, 2 active not recruiting, 2 recruiting, 2 unknown. 6 Phase 3, 5 Phase 1, 4 Phase 4, 3 Phase 2, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 6 |
| Phase 1 | 5 | Completed 2, Active not recruiting 1, Terminated 1, Unknown 1 |
| Phase 4 | 4 | Completed 3, Recruiting 1 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
| Not applicable | 1 | Completed 1 |
Follow Streptococcus Pneumoniae: new trials by email Literature Review of Streptococcus Pneumoniae trials Research Report on Streptococcus Pneumoniae
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective Dengue, Chikungunya | Recruiting | Institut Pasteur du Cambodge | 10000 | 2025-12-18 | 2026-01-22 | |
| A Study to Learn About How a New Pneumococcal Vaccine Works in Adults PG4 vaccine in Buffer 1 with low dose PA-001, PG4 in Buffer 1 with low dose PA-002, PG4 in Buffer 1 with high dose PA-001 - Streptococcus Pneumoniae | Phase 1 | Active not recruiting | Pfizer | 380 | 2025-07-22 | 2026-06-22 |
| Short Versus Long Duration of Therapy for Streptococcus Pneumoniae Bloodstream Infections pneumoniae bacteremia therapy - Streptococcus Pneumoniae | Active not recruiting | Methodist Health System | 200 | 2023-06-23 | 2025-07-04 | |
| Clinical Trial Assessing the Immunogenicity of an Anti-pneumococcal Vaccination Strategy (PCV13+PPV23 Versus PREVENAR20) in Adult Patients Treated for a Lymphoma Prevenar 13 + Pneumovax 23, PREVENAR20 - Vaccine, Streptococcus Pneumoniae | Phase 4 | Recruiting | Poitiers University Hospital | 160 | 2021-09-07 | 2026-05-29 |
| An Evaluation of PCV13 Vaccine Schedules, Comparing Impact of 2+1 vs 3+0 on Pneumococcal Carriage in Blantyre, Malawi nasopharyngeal swab - 13-valent Pneumococcal Vaccine, Streptococcus Pneumoniae | Completed | University of Liverpool | 3507 | 2019-07-21 | 2025-09-04 | |
| Carriage of Streptococcus Pneumoniae in Infants With Acute Otitis Media and in Infants Attending Day-care Centers Nasopharyngeal sampling with a swab - Streptococcus Pneumoniae, Nasopharyngeal Carriage | Not applicable | Completed | Pierre Van Damme | 2817 | 2015-10-01 | 2020-11-05 |
| PCV10 Immunogenicity Study Nepal 2015 10-valent pneumococcal conjugate vaccine - Streptococcus Pneumoniae | Phase 4 | Completed | University of Oxford | 304 | 2015-08-21 | 2018-01-11 |
| Immunogenicity and Safety of PCV13 and Fluad in Adults Aged ≥60 Years Fluad and Prevenar13, Fluad, Prevenar13 - Influenza, Streptococcus Pneumoniae | Phase 4 | Completed | Korea University Guro Hospital | 1195 | 2014-09-01 | 2015-04-01 |
| Community Acquired Pneumonia: Outcome, Quality of Life and Immune Status Prevnar 13 - Pneumonia, Streptococcus Pneumoniae | Phase 4 | Completed | St. Antonius Hospital | 60 | 2014-04-01 | 2014-12-23 |
| PICR-b Nasopharyngeal S. Pneumoniae and Nasal S. Aureus Carriage Study PCV - Streptococcus Pneumoniae | Unknown | Sheba Medical Center | 12800 | 2014-04-01 | 2017-02-27 | |
| Safety and Immunogenicity Study of Prophylactic Streptococcus Pneumoniae Vaccine Placebo, GEN-004 Low Dose, GEN-004 Low Dose + Adjuvant - Streptococcus Pneumoniae | Phase 1 | Completed | Genocea Biosciences, Inc. | 90 | 2013-11-01 | 2015-12-11 |
| Neisseria Meningitidis Burden of Disease Study Data collection, CSF samples testing - Streptococcus Pneumoniae, Neisseria Meningitidis | Completed | GlaxoSmithKline | 521 | 2013-01-01 | 2015-11-11 | |
| Costa Rica Epidemiological Study on S. Pneumoniae Blood culture, Other cultures per Clinical routine practice - Streptococcus Pneumoniae | Suspended | Instituto de Atención Pediátrica | 4000 | 2011-03-01 | 2014-03-26 | |
| Evaluating Vaccine Responses in Healthy Infants Receiving Their Routine Primary Immunisation According to the Accelerated United Kingdom Schedule at 2, 3 and 4 Months Streptococcus Pneumoniae | Completed | Prof. Elizabeth Miller | 93 | 2010-11-01 | 2019-03-22 | |
| Prevenar Special Use-result Surveillance in Japan (Regulatory PostMarketing Commitment Plan) 7-valent vaccine injection - Pneumococcal Vaccine, Streptococcus Pneumoniae | Completed | Pfizer | 1143 | 2010-09-01 | 2016-01-20 | |
| Vaccination With GSK 1024850A in Children Primed With GSK 1024850A & Boosted With Pneumovax 23™ Pneumococcal conjugate vaccine GSK 1024850A, Pneumococcal conjugate vaccine Prevenar™ (Wyeth Lederle's) - Infections, Streptococcal, Streptococcus Pneumoniae | Phase 3 | Completed | GlaxoSmithKline | 52 | 2009-06-23 | 2020-11-23 |
| Evaluation of Effectiveness of GSK Biologicals' Pneumococcal Conjugate Vaccine 1024850A Against Invasive Disease Pneumococcal conjugate vaccine GSK1024850A, GSK Biologicals' Engerix TM vaccine (Hepatitis B vaccine), GSK Biologicals' Havrix TM vaccine (Hepatitis A vaccine) - Infections, Streptococcal, Streptococcus Pneumoniae | Phase 3 | Completed | GlaxoSmithKline | 41188 | 2009-05-04 | 2020-12-17 |
| Impact of the 7 Valent Pneumococcal Conjugate Vaccine (7vPCV) on Nasopharyngeal Carriage of Streptococcus Pneumoniae in Healthy Jordanian Infants 7 valent pneumococcal conjugate vaccine (7v-PCV) - Prevenar - Streptococcus Pneumoniae | Phase 1 / Phase 2 | Unknown | German-Jordanian University | 377 | 2009-05-01 | 2009-09-30 |
| Study to Assess the Safety of a New GSK Biologicals' GSK2231395A Candidate Vaccine GSK2231395A, TwinrixTM - Haemophilus Influenzae, Streptococcus Pneumoniae | Phase 1 | Terminated | GlaxoSmithKline | 30 | 2009-03-12 | 2017-10-31 |
| Primary Vaccination Study With a Pneumococcal Conjugate Vaccine in Healthy Children 6 to 10 Weeks of Age Pneumococcal conjugate vaccine GSK1024850A, Tritanrix-HepB/Hib, Hiberix - Infections, Streptococcal, Streptococcus Pneumoniae | Phase 3 | Completed | GlaxoSmithKline | 360 | 2009-03-07 | 2020-01-03 |
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Haemophilus Infections (6) · Streptococcal Infections (4) · Otitis Media (3) · Pneumococcal Infections (2) · Pneumonia (2) · Adenoviridae Infections (1) · Arenaviridae Infections (1) · Brucellosis (1) · Bunyaviridae Infections (1) · Caliciviridae Infections (1) · Chickenpox (1) · Chikungunya Fever (1) · Chlamydia Infections (1) · Communicable Diseases (1) · Dengue (1)
Infections (12) · Bacterial Infections (9) · Bacterial Infections and Mycoses (9) · Gram-Negative Bacterial Infections (7) · Gram-Positive Bacterial Infections (6) · Pasteurellaceae Infections (6) · Respiratory Tract Diseases (4) · Ear Diseases (3) · Otitis (3) · Otorhinolaryngologic Diseases (3) · RNA Virus Infections (3) · Respiratory Tract Infections (3) · Urogenital Diseases (3) · Virus Diseases (3) · Genital Diseases (2)
13-valent pneumococcal vaccine (3) · Heptavalent Pneumococcal Conjugate Vaccine (3) · 10-valent pneumococcal conjugate vaccine (2) · Hepatitis A Vaccines (2) · Hepatitis B Vaccines (2) · Pneumococcal Vaccines (2) · 23-valent pneumococcal capsular polysaccharide vaccine (1) · Adjuvants, Pharmaceutic (1) · Blood Culture (1) · Data Collection (1) · Engerix-B (1) · Hiberix (1) · PHiD-CV vaccine (1) · Sodium Chloride (1) · Tritanrix-HepB vaccine (1)
GlaxoSmithKline (7) · Pfizer (2) · Public Health England (2) · Genocea Biosciences, Inc. (1) · German-Jordanian University (1) · Henry M. Jackson Foundation for the Advancement of Military Medicine (1) · Institut Pasteur du Cambodge (1) · Instituto de Atención Pediátrica (1) · Korea University Guro Hospital (1) · Methodist Health System (1) · NICHD Neonatal Research Network (1) · Pierre Van Damme (1) · Poitiers University Hospital (1) · Prof. Elizabeth Miller (1) · Sanofi Pasteur, a Sanofi Company (1)
United States (5) · Finland (2) · United Kingdom (2) · Belgium (1) · Cambodia (1) · Canada (1) · Costa Rica (1) · France (1) · Germany (1) · India (1) · Israel (1) · Japan (1) · Jordan (1) · Malawi (1) · Netherlands (1)
Elizabeth Miller, MBBS FRCPath (2) · Abhik Das, PhD (1) · Adnan AL-lahham, PhD (1) · Arturo Abdelnour, MD (1) · Barbara J. Stoll, MD (1) · Bart JM Vlaminckx, Phd (1) · Brian Agan, MD (1) · Carl T. D'Angio, MD (1) · Claude Flamand, Ph.D. (1) · Dror Harats, Prof. (1) · Elizabeth Coates, PhD (1) · Ger T Rijkers, Prof (1) · Gertjan H Wagenvoort, MD (1)
PMID 34986178, PMID 16567982, PMID 19814624, PMID 20234331, PMID 20795819, PMID 20887830, PMID 21135351, PMID 23158882, PMID 23370608, PMID 24173029, PMID 24287186, PMID 24569312, PMID 25008901, PMID 25127244, PMID 25424793, PMID 25510388, PMID 26284652, PMID 27125273, PMID 27919632, PMID 28802755, PMID 29503110, PMID 30145098, PMID 30635252, PMID 31122856, PMID 40884828
2008 (3), M01RR000030 (1), M01RR000032 (1), M01RR000039 (1), M01RR000044 (1), M01RR000070 (1), M01RR000633 (1), M01RR007122 (1), M01RR016587 (1), U01HD036790 (1), U10HD021385 (1), U10HD021397 (1), U10HD027851 (1), U10HD027880 (1), U10HD034216 (1)