11 completed, 7 recruiting, 5 active not recruiting, 3 terminated. 9 Not applicable, 9 Phase 2, 4 Phase 1, 3 Early Phase 1, 1 Phase 3.
Follow Stage IIIB Prostate Cancer AJCC v8: new trials by email Literature Review of Stage IIIB Prostate Cancer AJCC v8 trials Research Report on Stage IIIB Prostate Cancer AJCC v8
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Magnetic Resonance-Guided Stereotactic Body Radiation Therapy for the Treatment of Prostate Cancer Biopsy Procedure, Computed Tomography, Electronic Health Record Review - Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8 | Not applicable | Not yet recruiting | City of Hope Medical Center | 20 | 2027-01-01 | 2026-08-17 |
| Extending Prostate Genetic Awareness, Navigation, and Delivery: The EXPAND Network Training and Education, Educational Intervention, Discussion - Metastatic Prostate Carcinoma, Stage IIIB Prostate Cancer AJCC v8 | Recruiting | Thomas Jefferson University | 30 | 2024-06-03 | 2026-10-29 | |
| Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial Apalutamide, Biospecimen Collection, Computed Tomography - Prostate Adenocarcinoma, Stage II Prostate Cancer AJCC v8 | Phase 2 | Recruiting | Jonsson Comprehensive Cancer Center | 95 | 2024-03-28 | 2026-07-17 |
| Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation Biospecimen Collection, Carboplatin, Chest Radiography - Prostate Adenocarcinoma, Stage IIIB Prostate Cancer AJCC v8 | Phase 2 | Recruiting | SWOG Cancer Research Network | 44 | 2024-03-01 | 2026-01-29 |
| Focal Ablation With Focal Cryotherapy or HIFU for the Treatment of Men With Localized Prostate Cancer Cryosurgery, High-Intensity Focused Ultrasound Ablation, Survey Administration - Localized Prostate Carcinoma, Stage I Prostate Cancer AJCC v8 | Not applicable | Recruiting | University of California, Davis | 100 | 2023-11-09 | 2026-06-30 |
| MRI Guided Radiation Therapy for the Treatment of High Risk Prostate Cancer MRI-guided Intensity-Modulated Radiation Therapy, Antiandrogen Therapy, PSMA PET Scan - Prostate Adenocarcinoma, Stage IIIB Prostate Cancer AJCC v8 | Phase 2 | Terminated | Thomas Jefferson University | 6 | 2022-11-16 | 2026-03-03 |
| RElugolix VErsus LeUprolide Cardiac Trial Radiation therapy, Leuprolide, Relugolix - Biochemically Recurrent Prostate Carcinoma, Localized Prostate Carcinoma | Phase 2 | Active not recruiting | Emory University | 94 | 2022-06-06 | 2026-02-12 |
| Robot-Assisted Radical Prostatectomy With or Without Vesicopexy in Patients With Prostate Cancer Quality-of-Life Assessment, Questionnaire Administration, Radical Prostatectomy - Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8 | Not applicable | Suspended | University of Southern California | 196 | 2021-10-27 | 2026-06-01 |
| Pharmacokinetics of IA and IV Ga68-PSMA-11 Infusion Angiogram, Catheterization, Gallium Ga-labeled PSMA-11 - Prostate Adenocarcinoma, Prostate Carcinoma | Early Phase 1 | Completed | Ryan Kohlbrenner, MD | 5 | 2021-10-13 | 2023-04-07 |
| High Dose-Rate Brachytherapy and Stereotactic Body Radiotherapy for the Treatment of Prostate Adenocarcinoma High-Dose Rate Brachytherapy, Stereotactic Body Radiation Therapy - Prostate Adenocarcinoma, Stage IIB Prostate Cancer American Joint Committee on Cancer (AJCC) v8 | Not applicable | Recruiting | Jonsson Comprehensive Cancer Center | 52 | 2021-08-20 | 2026-08-20 |
| Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer Abiraterone Acetate, Antiandrogen Therapy, Apalutamide - Prostate Carcinoma, Stage IIC Prostate Cancer AJCC v8 | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 200 | 2021-08-05 | 2026-06-23 |
| Proton Radiation Therapy for the Treatment of Patients With High Risk Prostate Cancer High-Dose Rate Brachytherapy, Proton Beam Radiation Therapy, Quality-of-Life Assessment - Stage III Prostate Cancer AJCC v8, Stage IIIA Prostate Cancer AJCC v8 | Not applicable | Recruiting | Emory University | 30 | 2021-02-01 | 2026-02-17 |
| Health Literacy in Understanding Radiation Therapy Information in Patients Undergoing Definitive Radiation Therapy Survey Administration - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8 | Terminated | University of Southern California | 35 | 2020-12-18 | 2024-04-29 | |
| Technology-Enhanced Acceleration of Germline Evaluation for Therapy, TARGET Study Interview, Internet Based Intervention, Survey Administration - Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Carcinoma | Not applicable | Completed | Thomas Jefferson University | 346 | 2020-08-27 | 2025-12-02 |
| Randomized Trial of PSMA PET Scan Before Definitive Radiation Therapy for Prostate Cancer Computed Tomography, Fluorine F 18 DCFPyL, Positron Emission Tomography - Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8, Stage II Prostate Cancer AJCC v8 | Phase 3 | Terminated | Jonsson Comprehensive Cancer Center | 54 | 2020-08-14 | 2023-01-17 |
| An Investigational Scan (7 Tesla MRI) in Diagnosing Cognitive Impairment in Patients With Non-Metastatic Prostate Cancer 7 Tesla Magnetic Resonance Imaging - Non-Metastatic Prostate Carcinoma, Stage I Prostate Cancer AJCC v8 | Not applicable | Completed | University of Southern California | 20 | 2020-08-11 | 2025-03-17 |
| Remote Telemonitoring of Patient-Generated Physiologic Health Data and Patient-Reported Outcomes Patient Monitoring, Questionnaire Administration - Clinical Stage 0 Esophageal Adenocarcinoma AJCC v8, Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8 | Completed | City of Hope Medical Center | 22 | 2020-08-11 | 2026-10-14 | |
| Lifestyle Behavior Influences Among African American Patients With Stage 0-III Prostate Cancer Survivors and Their Partners Accelerometer, Ecological Momentary Assessment, Questionnaire Administration - Cancer Survivor, Partner | Active not recruiting | M.D. Anderson Cancer Center | 200 | 2020-02-26 | 2026-08-21 | |
| Daily, Long-Term Intermittent Fasting for the Prevention of PSA-Recurrence in Patients With Localized Prostate Cancer After Radical Prostatectomy Food Diary, Preventative Dietary Intervention, Questionnaire Administration - Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8 | Early Phase 1 | Withdrawn | Mayo Clinic | 2020-01-08 | 2022-07-11 | |
| Aspirin and Rintatolimod With or Without Interferon-alpha 2b in Treating Patients With Prostate Cancer Before Surgery EC Aspirin, Radical Prostatectomy, Recombinant Interferon Alfa-2b - Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8 | Phase 2 | Active not recruiting | Roswell Park Cancer Institute | 12 | 2019-11-29 | 2026-06-09 |
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Prostatic Neoplasms (30) · Ovarian Neoplasms (4) · Colorectal Neoplasms (3) · Pancreatic Neoplasms (2) · Urogenital Neoplasms (2) · Brain Neoplasms (1) · Breast Neoplasms (1) · Carcinoma, Renal Cell (1) · Gastrointestinal Neoplasms (1) · Lung Neoplasms (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Triple Negative Breast Neoplasms (1) · Urinary Bladder Neoplasms (1) · Uterine Cervical Neoplasms (1)
Genital Diseases (30) · Genital Diseases, Male (30) · Genital Neoplasms, Male (30) · Male Urogenital Diseases (30) · Neoplasms by Site (30) · Prostatic Diseases (30) · Urogenital Diseases (30) · Neoplasms (29) · Urogenital Neoplasms (28) · Adnexal Diseases (4) · Digestive System Diseases (4) · Digestive System Neoplasms (4) · Endocrine Gland Neoplasms (4) · Endocrine System Diseases (4) · Female Urogenital Diseases (4)
Magnetic Resonance Spectroscopy (7) · Specimen Handling (5) · Brachytherapy (3) · Radiation (3) · Radiotherapy (3) · Androgen Antagonists (2) · Biopsy (2) · Genetic Testing (2) · Glutamate Carboxypeptidase II (2) · Interviews as Topic (2) · Proton Therapy (2) · Radiosurgery (2) · Radiotherapy, Intensity-Modulated (2) · X-Rays (2) · apalutamide (2)
M.D. Anderson Cancer Center (7) · Jonsson Comprehensive Cancer Center (3) · Mayo Clinic (3) · Thomas Jefferson University (3) · University of Southern California (3) · City of Hope Medical Center (2) · Emory University (2) · National Cancer Institute (NCI) (2) · NRG Oncology (1) · Roswell Park Cancer Institute (1) · Ryan Kohlbrenner, MD (1) · SWOG Cancer Research Network (1) · University of California, Davis (1)
United States (30) · Canada (1) · Puerto Rico (1)
Dalnim Cho (2) · Alison M Schram (1) · Amar Kishan (1) · Amy Leader, DrPh, MPH (1) · Carlos E. Vargas, M.D. (1) · Gurkamal S Chatta (1) · Heather H Cheng (1) · Hooman Djaladat, MD (1) · Jeremie Calais (1) · Jessie DiNome, MD (1) · Jewel Samadder, M.D. (1) · Julius Weng (1) · Kimberly Miller, MD (1) · Laleh Melstrom (1) · Lorna McNeill (1)
PMID 33962579, PMID 35710085, PMID 36351402, PMID 38452310, PMID 38664019, PMID 39136560, PMID 39254446, PMID 40939237, PMID 41706486
P30CA014089 (3), P30CA016672 (2), P30CA033572 (2), P30CA138292 (2), P30CA015083 (1), P30CA093373 (1), U10CA180868 (1), U10CA180888 (1), UM1CA186691 (1)