11 completed, 6 active not recruiting, 5 recruiting, 2 suspended. 9 Not applicable, 9 Phase 2, 4 Phase 1, 3 Early Phase 1, 1 Phase 3.
Follow Stage IIIA Prostate Cancer AJCC v8: new trials by email Literature Review of Stage IIIA Prostate Cancer AJCC v8 trials Research Report on Stage IIIA Prostate Cancer AJCC v8
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Magnetic Resonance-Guided Stereotactic Body Radiation Therapy for the Treatment of Prostate Cancer Biopsy Procedure, Computed Tomography, Electronic Health Record Review - Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8 | Not applicable | Not yet recruiting | City of Hope Medical Center | 20 | 2027-01-01 | 2026-08-17 |
| Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial Apalutamide, Biospecimen Collection, Computed Tomography - Prostate Adenocarcinoma, Stage II Prostate Cancer AJCC v8 | Phase 2 | Recruiting | Jonsson Comprehensive Cancer Center | 95 | 2024-03-28 | 2026-07-17 |
| Focal Ablation With Focal Cryotherapy or HIFU for the Treatment of Men With Localized Prostate Cancer Cryosurgery, High-Intensity Focused Ultrasound Ablation, Survey Administration - Localized Prostate Carcinoma, Stage I Prostate Cancer AJCC v8 | Not applicable | Recruiting | University of California, Davis | 100 | 2023-11-09 | 2026-06-30 |
| RElugolix VErsus LeUprolide Cardiac Trial Radiation therapy, Leuprolide, Relugolix - Biochemically Recurrent Prostate Carcinoma, Localized Prostate Carcinoma | Phase 2 | Active not recruiting | Emory University | 94 | 2022-06-06 | 2026-02-12 |
| Robot-Assisted Radical Prostatectomy With or Without Vesicopexy in Patients With Prostate Cancer Quality-of-Life Assessment, Questionnaire Administration, Radical Prostatectomy - Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8 | Not applicable | Suspended | University of Southern California | 196 | 2021-10-27 | 2026-06-01 |
| Pharmacokinetics of IA and IV Ga68-PSMA-11 Infusion Angiogram, Catheterization, Gallium Ga-labeled PSMA-11 - Prostate Adenocarcinoma, Prostate Carcinoma | Early Phase 1 | Completed | Ryan Kohlbrenner, MD | 5 | 2021-10-13 | 2023-04-07 |
| Neoadjuvant Dietary Intervention in Intermediate Risk Prostate Cancer Dietary Intervention, Radical Prostatectomy - Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8 | Not applicable | Active not recruiting | M.D. Anderson Cancer Center | 12 | 2021-08-27 | 2026-09-18 |
| High Dose-Rate Brachytherapy and Stereotactic Body Radiotherapy for the Treatment of Prostate Adenocarcinoma High-Dose Rate Brachytherapy, Stereotactic Body Radiation Therapy - Prostate Adenocarcinoma, Stage IIB Prostate Cancer American Joint Committee on Cancer (AJCC) v8 | Not applicable | Recruiting | Jonsson Comprehensive Cancer Center | 52 | 2021-08-20 | 2026-08-20 |
| Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer Abiraterone Acetate, Antiandrogen Therapy, Apalutamide - Prostate Carcinoma, Stage IIC Prostate Cancer AJCC v8 | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 200 | 2021-08-05 | 2026-06-23 |
| White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or Therapy Naive Fav Risk Prostate CA Clinical Observation, Patient Observation, Questionnaire Administration - Prostate Adenocarcinoma, PSA Failure | Phase 2 | Suspended | City of Hope Medical Center | 133 | 2021-05-10 | 2026-08-10 |
| Proton Radiation Therapy for the Treatment of Patients With High Risk Prostate Cancer High-Dose Rate Brachytherapy, Proton Beam Radiation Therapy, Quality-of-Life Assessment - Stage III Prostate Cancer AJCC v8, Stage IIIA Prostate Cancer AJCC v8 | Not applicable | Recruiting | Emory University | 30 | 2021-02-01 | 2026-02-17 |
| Health Literacy in Understanding Radiation Therapy Information in Patients Undergoing Definitive Radiation Therapy Survey Administration - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8 | Terminated | University of Southern California | 35 | 2020-12-18 | 2024-04-29 | |
| Randomized Trial of PSMA PET Scan Before Definitive Radiation Therapy for Prostate Cancer Computed Tomography, Fluorine F 18 DCFPyL, Positron Emission Tomography - Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8, Stage II Prostate Cancer AJCC v8 | Phase 3 | Terminated | Jonsson Comprehensive Cancer Center | 54 | 2020-08-14 | 2023-01-17 |
| An Investigational Scan (7 Tesla MRI) in Diagnosing Cognitive Impairment in Patients With Non-Metastatic Prostate Cancer 7 Tesla Magnetic Resonance Imaging - Non-Metastatic Prostate Carcinoma, Stage I Prostate Cancer AJCC v8 | Not applicable | Completed | University of Southern California | 20 | 2020-08-11 | 2025-03-17 |
| Remote Telemonitoring of Patient-Generated Physiologic Health Data and Patient-Reported Outcomes Patient Monitoring, Questionnaire Administration - Clinical Stage 0 Esophageal Adenocarcinoma AJCC v8, Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8 | Completed | City of Hope Medical Center | 22 | 2020-08-11 | 2026-10-14 | |
| Lifestyle Behavior Influences Among African American Patients With Stage 0-III Prostate Cancer Survivors and Their Partners Accelerometer, Ecological Momentary Assessment, Questionnaire Administration - Cancer Survivor, Partner | Active not recruiting | M.D. Anderson Cancer Center | 200 | 2020-02-26 | 2026-08-21 | |
| Daily, Long-Term Intermittent Fasting for the Prevention of PSA-Recurrence in Patients With Localized Prostate Cancer After Radical Prostatectomy Food Diary, Preventative Dietary Intervention, Questionnaire Administration - Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8 | Early Phase 1 | Withdrawn | Mayo Clinic | 2020-01-08 | 2022-07-11 | |
| Aspirin and Rintatolimod With or Without Interferon-alpha 2b in Treating Patients With Prostate Cancer Before Surgery EC Aspirin, Radical Prostatectomy, Recombinant Interferon Alfa-2b - Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8 | Phase 2 | Active not recruiting | Roswell Park Cancer Institute | 12 | 2019-11-29 | 2026-06-09 |
| Testing the Addition of a New Anti-Cancer Drug, Niraparib, to the Usual Treatment (Hormone and Radiation Therapy) for Prostate Cancer With a High Chance of Recurring Gonadotrophin Releasing Hormone, Intensity-Modulated Radiation Therapy, Niraparib - Prostate Adenocarcinoma, Stage IIC Prostate Cancer AJCC v8 | Phase 1 / Phase 2 | Completed | NRG Oncology | 22 | 2019-10-08 | 2026-07-10 |
| Lifestyle Intervention for the Reduction of Prostate Cancer Disparities Among African Americans Exercise Intervention, Informational Intervention, Interview - Cancer Survivor, Partner | Not applicable | Active not recruiting | M.D. Anderson Cancer Center | 6 | 2019-08-27 | 2026-04-15 |
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Prostatic Neoplasms (29) · Ovarian Neoplasms (4) · Colorectal Neoplasms (3) · Pancreatic Neoplasms (2) · Urogenital Neoplasms (2) · Brain Neoplasms (1) · Breast Neoplasms (1) · Carcinoma, Renal Cell (1) · Gastrointestinal Neoplasms (1) · Lung Neoplasms (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Triple Negative Breast Neoplasms (1) · Urinary Bladder Neoplasms (1) · Uterine Cervical Neoplasms (1)
Genital Diseases (29) · Genital Diseases, Male (29) · Genital Neoplasms, Male (29) · Male Urogenital Diseases (29) · Neoplasms by Site (29) · Prostatic Diseases (29) · Urogenital Diseases (29) · Neoplasms (28) · Urogenital Neoplasms (27) · Adnexal Diseases (4) · Digestive System Diseases (4) · Digestive System Neoplasms (4) · Endocrine Gland Neoplasms (4) · Endocrine System Diseases (4) · Female Urogenital Diseases (4)
Magnetic Resonance Spectroscopy (5) · Brachytherapy (3) · Radiation (3) · Radiotherapy (3) · Specimen Handling (3) · apalutamide (3) · Abiraterone Acetate (2) · Biopsy (2) · Gonadotropin-Releasing Hormone (2) · Prednisone (2) · Proton Therapy (2) · Radiosurgery (2) · Radiotherapy, Intensity-Modulated (2) · deltacortene (2) · gallium 68 PSMA-11 (2)
M.D. Anderson Cancer Center (9) · City of Hope Medical Center (3) · Jonsson Comprehensive Cancer Center (3) · Mayo Clinic (3) · University of Southern California (3) · Emory University (2) · National Cancer Institute (NCI) (2) · NRG Oncology (1) · Roswell Park Cancer Institute (1) · Ryan Kohlbrenner, MD (1) · University of California, Davis (1)
United States (29) · Canada (1) · Puerto Rico (1)
Dalnim Cho (2) · Alison M Schram (1) · Amar Kishan (1) · Carlos E. Vargas, M.D. (1) · Christopher Logothetis (1) · Clayton S Lau (1) · Gurkamal S Chatta (1) · Hooman Djaladat, MD (1) · Jeremie Calais (1) · Jewel Samadder, M.D. (1) · Julius Weng (1) · Justin R Gregg (1) · Kimberly Miller, MD (1) · Laleh Melstrom (1) · Lorna McNeill (1)
PMID 33962579, PMID 36351402, PMID 38664019, PMID 39136560, PMID 39254446, PMID 39390760, PMID 40939237, PMID 41202201, PMID 41706486
P30CA014089 (3), P30CA033572 (3), P30CA016672 (2), P30CA138292 (2), P30CA015083 (1), P30CA093373 (1), P50CA140388 (1), U10CA180868 (1), UM1CA186691 (1)