3 completed, 3 recruiting, 2 unknown, 1 withdrawn. 4 Phase 1, 4 Phase 2, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 2, Recruiting 1, Unknown 1 |
| Phase 2 | 4 | Recruiting 2, Unknown 2 |
| Not applicable | 1 | Completed 1 |
Follow Squamous Cell Carcinoma of the Anus: new trials by email Literature Review of Squamous Cell Carcinoma of the Anus trials Research Report on Squamous Cell Carcinoma of the Anus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of IDP-001 in Advanced or Metastatic Solid Tumors IDP-001 - Advanced Solid Tumor, Metastatic Solid Tumor | Phase 1 / Phase 2 | Recruiting | InduPro, Inc. | 132 | 2026-07-08 | 2026-09-03 |
| ctHPVDNA Response-Adapted Chemoradiation +/- Retifanlimab Treatment in Locally-Advanced Anal Cancer HPV ctDNA Response based radiation, Chemotherapy, Retifanlimab - Anal Cancer, HPV-Related Carcinoma | Phase 2 | Recruiting | Jennifer Dorth | 33 | 2026-06-19 | 2026-08-14 |
| The Self-Sampling Pilot Study Inserting a swab 5 cm into the anus during self-sampling, Self-sampling with a swab by inserting the swab 3 cm into the anus. - Squamous Cell Carcinoma of the Anus | Not applicable | Completed | Medical College of Wisconsin | 50 | 2025-07-31 | 2026-01-27 |
| Identification of the Pathogenetic Mechanisms Underlying Squamous Cell Carcinomas Multiparameter analysis of each sample - Squamous Cell Carcinoma of the Head and Neck, Squamous Cell Carcinoma of the Anus | Recruiting | National Cancer Institute, Naples | 170 | 2023-09-25 | 2025-07-29 | |
| SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas SL-279252 - Squamous Cell Carcinoma of the Head and Neck, Melanoma | Phase 1 | Completed | Shattuck Labs, Inc. | 49 | 2019-03-26 | 2025-04-02 |
| A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors XmAb20717 - Melanoma, Breast Carcinoma | Phase 1 | Completed | Xencor, Inc. | 150 | 2018-07-10 | 2022-12-01 |
| PEN-866 in Patients With Advanced Solid Malignancies PEN-866 Sodium, fluorouracil, Folinic acid - Carcinoma, Endometrial Adenocarcinoma | Phase 1 / Phase 2 | Unknown | Tarveda Therapeutics | 340 | 2017-08-29 | 2022-02-17 |
| Study to Determine the Feasibility of Sentinel Node Biopsy in Patients With Anal Cancer Sentinel lymph node biopsy - Squamous Cell Carcinoma of the Anus | Withdrawn | The Christie NHS Foundation Trust | 2014-09-01 | 2015-06-03 | ||
| International Multicentre Study in Advanced Anal Cancer Comparing Cisplatin Plus 5 FU vs Carboplatin Plus Weekly Paclitaxel Cisplatin, 5-Fluorouracil (5-FU), Carboplatin - Squamous Cell Carcinoma of the Anus | Phase 2 | Unknown | Royal Marsden NHS Foundation Trust | 80 | 2013-12-01 | 2015-11-04 |
Anus Neoplasms (9) · Squamous Cell Carcinoma of Head and Neck (4) · Carcinoma, Non-Small-Cell Lung (2) · Carcinoma, Renal Cell (2) · Carcinoma, Squamous Cell (2) · Carcinoma, Transitional Cell (2) · Melanoma (2) · Neoplasm Metastasis (2) · Small Cell Lung Carcinoma (2) · Stomach Neoplasms (2) · Bile Duct Neoplasms (1) · Breast Neoplasms (1) · Carcinoma (1) · Carcinoma, Basal Cell (1) · Carcinoma, Hepatocellular (1)
Anus Diseases (9) · Digestive System Diseases (9) · Digestive System Neoplasms (9) · Gastrointestinal Diseases (9) · Gastrointestinal Neoplasms (9) · Intestinal Diseases (9) · Intestinal Neoplasms (9) · Neoplasms by Site (9) · Rectal Diseases (9) · Rectal Neoplasms (9) · Colorectal Neoplasms (8) · Neoplasms (8) · Neoplasms by Histologic Type (5) · Neoplasms, Glandular and Epithelial (5) · Carcinoma (4)
Fluorouracil (2) · Carboplatin (1) · Cisplatin (1) · Drug Therapy (1) · Leucovorin (1) · Paclitaxel (1) · Sentinel Lymph Node Biopsy (1) · niraparib (1)
InduPro, Inc. (1) · Jennifer Dorth (1) · Medical College of Wisconsin (1) · National Cancer Institute, Naples (1) · Royal Marsden NHS Foundation Trust (1) · Shattuck Labs, Inc. (1) · Tarveda Therapeutics (1) · The Christie NHS Foundation Trust (1) · Xencor, Inc. (1)
United States (7) · Australia (1) · Belgium (1) · Canada (1) · Italy (1) · Spain (1) · United Kingdom (1)
Alan Nyitray, PhD (1) · Andrew G Renehan (1) · Anish Thomas, MD (1) · Jennifer Dorth, MD, MHSc (1) · Maria Lina Tornesello, M.D. (1) · Sheela Rao, MD, FRCP (1) · Zequn Tang, MD (1)