4 unknown, 3 completed, 1 withdrawn. 8 Phase 1, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 8 | Unknown 4, Completed 3, Withdrawn 1 |
| Phase 2 | 7 | Completed 3, Unknown 3, Withdrawn 1 |
Follow Spondylolysis: new trials by email Literature Review of Spondylolysis trials Research Report on Spondylolysis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety Evaluation of ART352-L in Subjects Undergoing Posterolateral Spinal Fusion ART352-L - Degenerative Spondylolisthesis | Phase 1 / Phase 2 | Unknown | Ankasa Regenerative Therapeutics, Inc. | 12 | 2020-09-30 | 2020-10-12 |
| Clinical Effectiveness of Pre-operative Methadone in Single Level Lateral Transpsoas Interbody Fusions Methadone Hydrochloride, Oxycodone-Acetaminophen - Degenerative Disc Disease, Spondylolisthesis, Lumbar Region | Phase 1 | Unknown | The Methodist Hospital Research Institute | 150 | 2020-02-11 | 2020-01-29 |
| Safety and Preliminary Effectiveness of NVD-001 for the Treatment of Low Grade Degenerative Lumbar Spondylolisthesis NVD-001, Standard of Care - Spondylolisthesis | Phase 1 / Phase 2 | Completed | Novadip Biosciences | 48 | 2017-01-01 | 2021-08-13 |
| Safety Study of Mesenchymal Stem Cells and Spinal Fusion XCEL-MT-OSTEO-ALPHA, Standard treatment - Lumbar Spondylolisthesis Involving L4-L5, and/or, Degenerative Discopathy Involving L4-L5 | Phase 1 / Phase 2 | Completed | Banc de Sang i Teixits | 69 | 2012-07-19 | 2020-01-21 |
| Pilot Study to Assess Safety/Preliminary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Prefix (AMPLEX) B2A Peptide Enhanced Ceramic Granules, Iliac crest autograft - Degenerative Disc Disease, Spondylolisthesis | Phase 1 / Phase 2 | Unknown | BioSurface Engineering Technologies, Inc | 22 | 2008-11-01 | 2012-03-09 |
| Pilot Study to Assess Safety/Prelimary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Prefix (AMPLEX) B2A Peptide Enhanced Ceramic Granules, Iliac crest autograft - Degenerative Disc Disease, Spondylolisthesis | Phase 1 / Phase 2 | Unknown | BioSurface Engineering Technologies, Inc | 24 | 2008-11-01 | 2012-03-09 |
| Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion PLF with autograft, PLF with NeoFuse - Degenerative Disc Disease, Degenerative Spondylolisthesis | Phase 1 / Phase 2 | Withdrawn | Mesoblast, Ltd. | 2008-11-01 | 2020-06-02 | |
| Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF) NeoFuse, posterolateral spinal fusion with instrumentation - Degenerative Disc Disease, Spondylolisthesis | Phase 1 / Phase 2 | Completed | Mesoblast, Ltd. | 6 | 2007-10-01 | 2020-06-29 |
Spondylolisthesis (8) · Intervertebral Disc Degeneration (6) · Spinal Stenosis (2) · Back Pain (1)
Bone Diseases (8) · Musculoskeletal Diseases (8) · Spinal Diseases (8) · Spondylosis (8) · Neurologic Manifestations (1) · Pain (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1)
Spinal Fusion (2) · Methadone (1) · Standard of Care (1) · Transplantation, Autologous (1) · oxycodone-acetaminophen (1)
BioSurface Engineering Technologies, Inc (2) · Mesoblast, Ltd. (2) · Ankasa Regenerative Therapeutics, Inc. (1) · Banc de Sang i Teixits (1) · Novadip Biosciences (1) · The Methodist Hospital Research Institute (1)
United States (4) · Belgium (1) · Canada (1) · Czechia (1) · Poland (1) · Spain (1)
Donna Skerrett, MD (2) · Brent Atkinson, PhD (1) · Christian Raftopoulos, MD, PhD (1) · David M Hooper, PhD (1) · Denis Dufrane, MD, PhD (1) · Sean M Barber, MD (1)
2016 (1)