72 completed, 26 recruiting, 22 unknown, 10 active not recruiting. 82 Not applicable, 7 Phase 2, 3 Phase 1, 3 Phase 3, 1 Early Phase 1.
Follow Spinal Dysraphism: new trials by email Literature Review of Spinal Dysraphism trials Research Report on Spinal Dysraphism
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Motor Imagery-Supported Thoracic Expansion in Children With Spina Bifida Thoracic Expansion Exercises, Motor Imagery-Supported Thoracic Expansion Exercises - Spina Bifida | Not applicable | Not yet recruiting | Karabuk University | 30 | 2026-10-12 | 2026-09-29 |
| tSCS in Children With Spina Bifida Transcutaneous stimulator - Spina Bifida, Myelomeningocele | Not applicable | Recruiting | Bailey Petersen | 20 | 2026-09-30 | 2026-09-15 |
| Clinical Investigation to Validate the Safety and Performance of the ABLE Kids Device in Pediatric Patients With Neurological Gait Disorders in a Clinical Setting ABLE Kids - Gait Impairment, Cerebral Palsy (CP) | Not applicable | Recruiting | ABLE Human Motion S.L. | 15 | 2026-09-01 | 2026-09-08 |
| Enema Device for Children With Spina Bifida Use of the foley catheter assistive device - Spina Bifida, Fecal Incontinence | Not applicable | Recruiting | University of Colorado, Denver | 20 | 2026-08-11 | 2026-09-03 |
| Coupled Gentamicin-Lactobacillus Rhamnosus in NLUTD Gentamicin, Lactobacillus Rhamnosus GG - Spinal Cord Injury, Neurogenic Bladder (NB) | Early Phase 1 | Not yet recruiting | Medstar Health Research Institute | 48 | 2026-08-01 | 2026-08-21 |
| Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults Extension assist knee ankle foot orthosis (EA-KAFO) - Muscle Weakness, Problems Moving Their Arms and Legs | Recruiting | National Institutes of Health Clinical Center (CC) | 23 | 2026-06-23 | 2026-07-23 | |
| Establishing the Preliminary Utility of a Novel Pediatric Manual Mobile Standing Wheelchair PedMMSWC Wheelchair User Testing, PedMMSWC Simulated Home, School, Community Environment - Spina Bifida | Not applicable | Recruiting | Optimal Mobility, Inc | 30 | 2026-06-18 | 2026-06-24 |
| Spina Bifida Healthcare Navigator Program Behavioral Treatment - Spina Bifida | Not applicable | Active not recruiting | University of Pittsburgh | 24 | 2026-04-15 | 2026-06-04 |
| Folic Acid Salt Study (FISFA Zambia) Fortified Iodized Salt with Folic Acid (FISFA) - Folate Deficiency, Neural Tube Defects | Not applicable | Recruiting | University of Alabama at Birmingham | 250 | 2026-04-10 | 2026-06-29 |
| Bowel Continence Across the Lifespan in People With Spina Bifida Retrograde Enema, Antegrade Enema - Spina Bifida, Neurogenic Bowel | Recruiting | David Chu | 943 | 2026-04-01 | 2026-09-24 | |
| Efficacy of Intravesical Oxybutynin in Children With Neurogenic Bladder Dysfunction Oxybutynin Hydrochloride, Placebo - Spina Bifida | Phase 3 | Recruiting | Central Hospital, Nancy, France | 60 | 2026-01-15 | 2026-04-14 |
| Transcutaneous Tibial Nerve Stimulation (TTNS) Treatment in Spina Bifida Pediatric Patients With Neurogenic Bladder Transcutaneous Tibial Nerve Stimulation (TTNS) treatment - Spina Bifida | Not applicable | Recruiting | University of Texas Southwestern Medical Center | 12 | 2025-11-18 | 2026-02-12 |
| Comparing Digitally and Traditionally Made Ankle Foot Orthoses Part A First Wear Period: Traditional AFO(s), Part A First Wear Period: Digital AFO(s), Part A Second Wear Period: Traditional AFO(s) - Flaccid Paresis, Spastic Paresis | Not applicable | Recruiting | Holland Bloorview Kids Rehabilitation Hospital | 50 | 2025-09-05 | 2025-11-20 |
| Effectiveness of Multimodal Therapy for Urinary Incontinence in Pediatric Spina Bifida Diet and Toileting Education, Pelvic Floor Physiotherapy, Abdominal Strengthening Program. - Myelomeningocele Spina Bifida, Spina Bifida, Open | Not applicable | Completed | Cairo University | 66 | 2025-09-01 | 2026-04-01 |
| Transcutaneous Spinal Stimulation for Children and Youth With Spina Bifida Transcutaneous stimulation - Myelomeningocele, Spina Bifida | Not applicable | Recruiting | Mayo Clinic | 30 | 2025-08-07 | 2025-10-14 |
| Autologous Human Umbilical Cord Tissue Patch for Postnatal Closure of Open Neural Tube Defects Autologous umbilical cord patch - Spina Bifida | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 15 | 2025-08-05 | 2026-09-24 |
| Fetoscopic Robotic Open Spina Bifida Treatment Fetoscopic robotic open spina bifida closure - Fetal Congenital Abnormalities, Fetoscopy | Not applicable | Not yet recruiting | Mount Sinai Hospital, Canada | 15 | 2025-07-01 | 2025-05-07 |
| Plyometric vs Resistance Training for Trunk Balance in Children With Spina Bifida upper extremity plyometric exercises, upper extremity resistance exercises - Spina Bifida, Balance Changes | Not applicable | Completed | Okan University | 28 | 2025-03-01 | 2025-08-15 |
| High Intensity Exercise and Improving Physical Activity Among People With Neurologic Dysfunction Participate in high intensity exercise of at least 20 minutes in 60 minutes session of RPE greater than 6. - Cerebral Palsy (CP), Stroke | Not applicable | Completed | University of Hartford | 15 | 2025-02-24 | 2025-11-03 |
| Assessing Transition Practices for Children With Disabilities: Pathways to a Successful Adulthood Chart review, Semi-structured interview - Spina Bifida, Cerebral Palsy | Completed | Centre Hospitalier Universitaire de Saint Etienne | 128 | 2025-02-14 | 2026-07-16 |
Showing 20 of 144. Sign in to see all of them.
Cerebral Palsy (35) · Spinal Cord Injuries (30) · Meningomyelocele (27) · Neural Tube Defects (19) · Urinary Bladder, Neurogenic (18) · Muscular Dystrophies (9) · Arnold-Chiari Malformation (6) · Multiple Sclerosis (6) · Spina Bifida Cystica (6) · Stroke (6) · Brain Injuries (5) · Congenital Abnormalities (5) · Urinary Tract Infections (5) · Brain Injuries, Traumatic (4)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (143) · Nervous System Malformations (142) · Nervous System Diseases (141) · Congenital Abnormalities (139) · Neural Tube Defects (125) · Central Nervous System Diseases (50) · Pathological Conditions, Signs and Symptoms (41) · Brain Diseases (38) · Signs and Symptoms (36) · Brain Damage, Chronic (35) · Trauma, Nervous System (32) · Wounds and Injuries (32) · Neurologic Manifestations (30) · Urogenital Diseases (30) · Female Urogenital Diseases and Pregnancy Complications (28)
Fetoscopy (5) · Surveys and Questionnaires (4) · Health Resources (3) · Blood Specimen Collection (2) · Folic Acid (2) · Urinary Sphincter, Artificial (2) · Acetazolamide (1) · Administration, Intravesical (1) · Behavior Therapy (1) · Breathing Exercises (1) · Case-Control Studies (1) · Diet (1) · Electric Stimulation Therapy (1) · Equipment and Supplies (1) · Factor IX (1)
Rennes University Hospital (7) · Holland Bloorview Kids Rehabilitation Hospital (4) · McGill University (4) · University Hospital, Clermont-Ferrand (4) · University of Alabama at Birmingham (4) · Assistance Publique - Hôpitaux de Paris (3) · Baylor College of Medicine (3) · Medstar Health Research Institute (3) · National Institutes of Health Clinical Center (CC) (3) · The University of Texas Health Science Center, Houston (3) · Universitaire Ziekenhuizen KU Leuven (3) · University of Pittsburgh (3) · Central Hospital, Nancy, France (2) · Erasmus Medical Center (2) · Gillette Children's Specialty Healthcare (2)
United States (62) · France (20) · Canada (15) · Turkey (Türkiye) (9) · Belgium (4) · Denmark (3) · Netherlands (3) · South Korea (3) · Spain (3) · Norway (2) · Bangladesh (1) · Brazil (1) · Croatia (1) · Egypt (1) · Georgia (1)
Dana Anaby, PhD (4) · Thomas C Bulea, Ph.D. (3) · Christelle Destinval, MD (2) · Jogi Pattisapu, MD (2) · Ramen Chmait, MD (2) · Ramesha Papanna, MD, MPH (2) · Ruben Quintero, MD (2) · Adrienne Kovacs, PhD,CPsych (1) · Ahmet Baschat, MD (1) · Amanda Garver, DO (1) · Amy McPherson, PhD (1) · Anastasia A Smith, DrPH (1) · Andi Saptono, Ph.D. (1) · Andrew Chon (1)
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K23DK119368 (1), R01DK084034 (1), R01DK110749 (1), R01HD039081 (1), R01HD119340 (1), R44HD118822 (1), U01HD068541 (1)