23 completed, 12 unknown, 9 active not recruiting, 9 recruiting. 34 Not applicable, 4 Phase 1, 3 Phase 2, 1 Phase 3, 1 Phase 4.
Follow Meningomyelocele: new trials by email Literature Review of Meningomyelocele trials Research Report on Meningomyelocele
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| tSCS in Children With Spina Bifida Transcutaneous stimulator - Spina Bifida, Myelomeningocele | Not applicable | Recruiting | Bailey Petersen | 20 | 2026-09-30 | 2026-09-15 |
| Spina Bifida Healthcare Navigator Program Behavioral Treatment - Spina Bifida | Not applicable | Active not recruiting | University of Pittsburgh | 24 | 2026-04-15 | 2026-06-04 |
| Transcutaneous Spinal Stimulation for Children and Youth With Spina Bifida Transcutaneous stimulation - Myelomeningocele, Spina Bifida | Not applicable | Recruiting | Mayo Clinic | 30 | 2025-08-07 | 2025-10-14 |
| Autologous Human Umbilical Cord Tissue Patch for Postnatal Closure of Open Neural Tube Defects Autologous umbilical cord patch - Spina Bifida | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 15 | 2025-08-05 | 2026-09-24 |
| Efficacy Of Pulsed Electromagnetic Field Therapy On Neurogenic Bladder in Children With Myelomeningocele pulsed electromagnetic field therapy device - Neurogenic Bladder | Not applicable | Active not recruiting | South Valley University | 40 | 2025-05-27 | 2025-12-15 |
| Dual Task and Upper Extremity Performance in Children With Myelomeningocele Single Task (Box and Block Test), Single Task (Nine Hole Peg Test), Dual Task (Box and Block Test-Kognitif Task) - Meningomyelocele | Completed | Abant Izzet Baysal University | 60 | 2025-05-26 | 2025-12-26 | |
| Prenatal and Postnatal Ultrasonographic Evaluation of Myelomeningocele to Predict Post-Surgical Outcomes G.E HEALTHCARE ultrasound machine with high-resolution convex probe - Myelomeningocele | Active not recruiting | Superior University | 20 | 2025-03-17 | 2025-07-02 | |
| In Utero Surgery for Fetal Myelomeningocele: Decision-making Mechanisms and Psychological Impact of Prenatal Therapy Semi-structured interviews with a psychologist - Myelomeningocele | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 44 | 2024-09-23 | 2025-01-28 |
| The Role of CSF in Chiari II Brain Malformation collection of cerebrospinal fluid - Myelomeningocele, Brain Malformation | Not yet recruiting | University College, London | 18 | 2024-09-01 | 2024-08-21 | |
| Inflammatory Response in Children Suffering From Tethered Cord CSF sampling during surgery - Tethered Spinal Cord, Including Thickened Filum, Lipomas, Myelomeningocele and Meningocele | Not applicable | Completed | University Hospital, Lille | 32 | 2024-05-16 | 2026-05-28 |
| Role of Perforator Flaps in Back Defects Reconstruction surgical closure of myelomeningocele defects by perforator flaps, surgical closure of myelomeningocele defects by perforator-plus flaps - Myelomeningocele | Not applicable | Unknown | Assiut University | 30 | 2024-05-01 | 2024-05-08 |
| Outcomes of Proactive Management of Children With Myelomeningocele CIC, Anticholinergic - Urologic Diseases | Unknown | Assiut University | 40 | 2024-03-04 | 2024-03-08 | |
| Operating Room Extubation and Postoperative Outcomes in Neonates With Meningomyelocele Myelomeningocele, Extubation Time | Active not recruiting | Gaziantep City Hospital | 60 | 2023-11-01 | 2026-03-11 | |
| Cryopreserved Human Umbilical Cord as a Meningeal Patch in Fetoscopic Spina Bifida Repair NEOX Cord 1K applied fetoscopically - Spina Bifida; Fetus, Myelomeningocele | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 100 | 2023-09-08 | 2025-08-13 |
| Safety and Efficacy of Devices Used in Fetoscopic Neural Tube Defect Repair Cases Modified Surgical Instruments/Devices (Sheaths and Irrigator) - Neural Tube Defects | Not applicable | Recruiting | Michael A Belfort | 100 | 2022-11-14 | 2025-12-15 |
| Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CIC Vibegron - Neurogenic Detrusor Overactivity | Phase 2 / Phase 3 | Recruiting | Urovant Sciences GmbH | 71 | 2022-10-12 | 2026-06-15 |
| Maternal-fetal Immune Responses to Fetal Surgery Blood and placenta specimen collection. - Spina Bifida, Congenital Diaphragmatic Hernia | Completed | Mayo Clinic | 21 | 2022-03-24 | 2026-02-10 | |
| the Effects of Platelet-Rich Plasma on Postoperative Complications After Meningomyelocele Use of Platelet-Rich Plasma after meningomyelocele sac repair, meningomyelocele sac repair - Meningomyelocele/Spina Bifida | Not applicable | Completed | Yuzuncu Yil University | 40 | 2022-01-15 | 2023-02-03 |
| Cellular Therapy for In Utero Repair of Myelomeningocele - The CuRe Trial Placental Mesenchymal Stem Cells seeded on a commercially available dural graft extracellular matrix, Untreated contemporaneous cohort - Myelomeningocele | Phase 1 / Phase 2 | Recruiting | University of California, Davis | 55 | 2021-06-21 | 2026-01-20 |
| Efficacy of Contrast Enhanced Voiding Urosonography for Urodynamic Studies Contrast Enhanced Voiding Urosonography with Urodynamic Testing, Urodynamic Testing - Myelomeningocele, Neurogenic Bladder | Unknown | University of Virginia | 105 | 2021-03-02 | 2021-04-28 |
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Spinal Dysraphism (26) · Neural Tube Defects (10) · Arnold-Chiari Malformation (6) · Urinary Bladder, Neurogenic (6) · Meningocele (4) · Spinal Cord Injuries (4) · Cerebral Palsy (3) · Congenital Abnormalities (3) · Spina Bifida Cystica (3) · Brain Injuries, Traumatic (2) · Central Nervous System Diseases (2) · Fetal Diseases (2) · Hernias, Diaphragmatic, Congenital (2) · Stroke (2)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (58) · Nervous System Diseases (58) · Nervous System Malformations (58) · Congenital Abnormalities (55) · Neural Tube Defects (48) · Pathological Conditions, Signs and Symptoms (16) · Female Urogenital Diseases and Pregnancy Complications (11) · Signs and Symptoms (11) · Urogenital Diseases (11) · Female Urogenital Diseases (8) · Male Urogenital Diseases (8) · Neurologic Manifestations (7) · Urinary Bladder Diseases (7) · Central Nervous System Diseases (6) · Hernia (6)
Fetoscopy (5) · Behavior Therapy (1) · Blood Specimen Collection (1) · Botulinum Toxins, Type A (1) · Cholinergic Antagonists (1) · Diffusion Tensor Imaging (1) · Equipment and Supplies (1) · Low-Level Light Therapy (1) · N-(4-((5-(hydroxy(phenyl)methyl)pyrrolidin-2-yl)methyl)phenyl)-4-oxo-4,6,7,8-tetrahydropyrrolo(1,2-a)pyrimidine-6-carboxamide (1) · Polysomnography (1) · Quality of Life (1) · Terbutaline (1) · Transcutaneous Electric Nerve Stimulation (1) · Ultrasonography (1) · Urodynamics (1)
The University of Texas Health Science Center, Houston (4) · Assistance Publique - Hôpitaux de Paris (3) · Assiut University (3) · Baylor College of Medicine (3) · University Children's Hospital, Zurich (3) · Mayo Clinic (2) · St. Louis University (2) · Abant Izzet Baysal University (1) · Bailey Petersen (1) · Gaziantep City Hospital (1) · Hospital Israelita Albert Einstein (1) · Hospital Universitari Vall d'Hebron Research Institute (1) · Hospital de Clinicas de Porto Alegre (1) · Indiana University (1) · Istanbul Science University (1)
United States (28) · France (5) · Switzerland (4) · Turkey (Türkiye) (4) · Egypt (3) · Belgium (2) · Brazil (2) · Denmark (2) · Canada (1) · Colombia (1) · Croatia (1) · Georgia (1) · Jordan (1) · Latvia (1) · Lithuania (1)
Ramen Chmait, MD (2) · Ramesha Papanna, MD, MPH (2) · Ruben Quintero, MD (2) · Ahmad Elderwy, prof (1) · Ahmet Baschat, MD (1) · Awni M Shawkat, MD (1) · Bailey Petersen, PhD (1) · Bettina Jorgensen, MD (1) · Brasil S Neto (1) · Christoph Stippich, Prof (1) · Corinna Gerber, MSc (1) · Diana L Farmer, MD (1) · Edna Gruenblatt, PhD (1)
PMID 21306277, PMID 34162982, PMID 39486058, PMID 10389801, PMID 11605920, PMID 11892506, PMID 14501247, PMID 15098220, PMID 15681999, PMID 15710013, PMID 15892823, PMID 15928511, PMID 17696520, PMID 18417993, PMID 18481813, PMID 18545825, PMID 18703879, PMID 19244697, PMID 21705180, PMID 21707563, PMID 22875857, PMID 23025445, PMID 23070089, PMID 23298791, PMID 23508219, PMID 23546436, PMID 23641451, PMID 24238105, PMID 24382623, PMID 24404708, PMID 24459624, PMID 24498490, PMID 24860935, PMID 25068670, PMID 25520824, PMID 25735902, PMID 25834962, PMID 25923030, PMID 26369371, PMID 26416930, PMID 26566108, PMID 27008504, PMID 27263997, PMID 27496687, PMID 28277363, PMID 28547209, PMID 29105387, PMID 29246577, PMID 29311854, PMID 29733310
K23DK119368 (1), R01HD119340 (1), R01HL147261 (1), U01HD068541 (1)