60 completed, 11 unknown, 5 not yet recruiting, 5 terminated. 78 Not applicable, 2 Phase 2, 2 Phase 3, 1 Phase 1, 1 Phase 4.
Follow Skin Laxity: new trials by email Literature Review of Skin Laxity trials Research Report on Skin Laxity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prospective Clinical Investigation to Evaluate the Safety and Effectiveness of Juläine™ in Improving Gluteal Skin Laxity in Adults. Poly-L-Lactic Acid (Juläine™) - Skin Quality, Skin Laxity | Not applicable | Not yet recruiting | Nordberg Medical AB | 100 | 2026-10-01 | 2026-03-19 |
| Evaluation of SofWave Sofware-Guided Energy Delivery for Lower Face and Neck Rejuvenation SofWave - Facial Wrinkles, Jawline Contour | Not applicable | Not yet recruiting | Sofwave Medical LTD | 30 | 2026-07-20 | 2026-07-27 |
| PLLA-LASYNPRO™ Injections for Skin Laxity Treatment PLLA Injection - Skin Laxity | Not applicable | Recruiting | Nordberg Medical Italy srl | 15 | 2026-05-13 | 2026-06-09 |
| Regenmedic Cream 2.0 12-week Long-term Clinical Test Test facial cream (topical skin care product) - Facial Photoaging, Deepening of Facial Wrinkles | Not applicable | Completed | ChinaNorm | 70 | 2026-04-13 | 2026-10-14 |
| Assess Efficacy of a Nanodiamond Periprocedural Skin Care Regimen for Ablative Resurfacing Pavise Serum, Sham Comparator, Co2/Er:YAG - Skin Laxity | Phase 2 | Not yet recruiting | Goldman, Butterwick, Fitzpatrick and Groff | 8 | 2026-03-20 | 2026-03-10 |
| RESTRUCTURING THE MANDIBULAR ANGLE IN FACIAL AGING: A NOVEL TECNIQUE USING POLY-L-LACTIC ACID PLLA application to the mandibular angle - Skin Laxity, Facial Aging | Not applicable | Not yet recruiting | Doris Hexsel | 46 | 2026-02-01 | 2025-11-26 |
| Safety and Efficacy of 2910 nm Fiber Laser Resurfacing and Laser-Coring 2,910 nm mid-infrared erbium-doped fluoride fiber glass laser (UltraClear, Acclaro Medical) - Rhytids, Skin Laxity | Not applicable | Active not recruiting | FA Corporation | 40 | 2025-11-24 | 2026-09-01 |
| A Study to Characterize Human Skin Changes From Biostimulator Treatments Via Non-invasive Imaging Sculptra® - Volume Deficiency in the Mid-Face, Skin Laxity | Not applicable | Recruiting | Galderma R&D | 25 | 2025-10-21 | 2026-02-10 |
| Ellacor® Micro-Coring Technology® in Fitzpatrick Skin Types I-VI, Including Patients Receiving Glucagon-Like Peptide-1 Receptor Agonists ellacor - glp1 Agonist, Gene Expression | Completed | Cytrellis Biosystems, Inc. | 9 | 2025-10-14 | 2026-10-05 | |
| DMAE Oleate for Facial Skin Firmness and Fine Lines in Healthy Adults Topical DMAE Oleate - Skin Aging of Face and Hands, Facial Wrinkles - Rough Texture - Hyperpigmentation | Not applicable | Completed | Bionos Biotech S.L. | 30 | 2025-09-09 | 2026-01-30 |
| An Evaluation of the Erchonia Laser As a Non-Invasive Treatment to Improve the Appearance of Skin Laxity Erchonia GVS Laser - Skin Laxity | Not applicable | Terminated | Erchonia Corporation | 9 | 2025-05-30 | 2026-06-10 |
| Quantified Evaluation of Noninvasive System Delivering Microwave Energy for Unwanted Fat Reduction and Skin Tightening in Asians. Facial Aging, Skin Laxity | Not yet recruiting | Chang Chang Cheng | 15 | 2025-05-01 | 2025-04-13 | |
| Clinical Study to Evaluate the Efficacy and Safety of Matrix Pro Treatment Profound Matrix - Skin Laxity, Wrinkle | Not applicable | Enrolling by invitation | Candela Corporation | 60 | 2025-01-28 | 2025-06-15 |
| Safety and Efficacy Evaluation of High Intensity Focused Ultrasound Device in Eyebrow Lifting HIFU treatment with ULTRAFOMER MPT - Skin Laxity, Wrinkles | Not applicable | Completed | CLASSYS Inc. | 180 | 2024-11-18 | 2026-05-15 |
| Benefit of Bovine or Marine Collagen Vs. Placebo on Skin, Hair, Nails and Whole Body Health in Healthy Adults Bovine or Marine Collagen - Skin Laxity, Hair Thinning | Not applicable | Unknown | Ancient + Brave | 90 | 2024-08-26 | 2024-09-19 |
| Device for Improving Skin Quality and Texture on the Face and Neck Treatment with BTL-785F - Wrinkle, Pigmentation | Not applicable | Completed | BTL Industries Ltd. | 39 | 2024-06-24 | 2025-09-16 |
| Evaluation of the Effects of a Biostimulator and Dermal Fillers for Cheek Augmentation and Contour Deficiencies Sculptra treatment, Restylane Treatment - Photoaging, Weight Loss | Not applicable | Completed | Galderma R&D | 41 | 2024-02-19 | 2026-04-15 |
| Histological Study of the Effects of a 2910 nm Fiber Laser Technology 2910 nm Fiber Laser Treatment; Pre-Clinical Histology Evaluation, 2910 nm Fiber Laser Treatment; Part 2 Histology Evaluation - Skin Laxity | Not applicable | Unknown | FA Corporation | 2 | 2024-02-05 | 2024-03-19 |
| Effects of QUANTUM Probe for Skin Rejuvenation and Subdermal Retraction in Patients Undergoing High-Definition Liposculpture Quantum RF - Skin Laxity, Skin Tightening | Not applicable | Recruiting | Total Definer Research Group | 80 | 2024-02-01 | 2025-05-06 |
| Histological Evaluation of Human Skin Bx to Assess the Effects of APR Tx as an Adjunct Procedure in Facelift Surgery Renuvion APR System - Skin Laxity, Tissue Degeneration | Not applicable | Completed | Apyx Medical | 7 | 2023-11-30 | 2026-03-24 |
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Cutis Laxa (91) · Cicatrix (3) · Skin Diseases (3) · Alopecia (2) · Hypertrophy (2) · Lipodystrophy (2) · Striae Distensae (2) · Weight Loss (2) · Contracture (1) · Dry Eye Syndromes (1) · Eyelid Diseases (1) · Facies (1) · Fatigue (1) · Hyperpigmentation (1) · Meibomian Gland Dysfunction (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (91) · Connective Tissue Diseases (91) · Genetic Diseases, Inborn (91) · Skin Diseases, Genetic (91) · Skin and Connective Tissue Diseases (91) · Skin Diseases (88) · Pathological Conditions, Signs and Symptoms (11) · Signs and Symptoms (6) · Pathologic Processes (4) · Pathological Conditions, Anatomical (4) · Fibrosis (3) · Body Weight (2) · Body Weight Changes (2) · Eye Diseases (2) · Hair Diseases (2)
Saline Solution (2) · Sunscreening Agents (2) · Ceramides (1) · Deuterium Oxide (1) · Ibuprofen (1) · Keratins (1) · New-Fill (1) · Sun Protection Factor (1) · Therapeutics (1) · astaxanthine (1) · incobotulinumtoxinA (1) · oxycodone-acetaminophen (1)
Ulthera, Inc (21) · Goldman, Butterwick, Fitzpatrick and Groff (4) · Sofwave Medical LTD (4) · Apyx Medical (3) · BTL Industries Ltd. (3) · Candela Corporation (3) · Lumenis Be Ltd. (3) · Recros Medica, Inc. (3) · Botanee Group Co., Ltd. (2) · Cynosure, Inc. (2) · FA Corporation (2) · Galderma R&D (2) · Revision Skincare (2) · Sciton (2) · University of Texas Southwestern Medical Center (2)
United States (63) · China (7) · Italy (3) · France (2) · Spain (2) · United Kingdom (2) · Brazil (1) · Bulgaria (1) · Canada (1) · Colombia (1) · Egypt (1) · Greece (1) · Indonesia (1) · Netherlands (1) · Taiwan (1)
Gordon Sasaki, MD (3) · Jeffrey Kenkel, MD (3) · Kari Larson, MBA (3) · Yun Wang, MD (3) · Hema Sundaram, MD (2) · Jay Burns, MD (2) · Konika Schallen, MD (2) · Robin McIntosh (2) · Ruthie Amir, MD (2) · Adela Serrano Gimeno, PhD (1) · Adele Sparavigna, MD (1) · Arielle Kauvar, MD (1) · Aris Sterodimas, MD (1) · Avishai Tzur (1)
PMID 41286587, PMID 25065380, PMID 27047630, PMID 36533797, PMID 40041776