1 completed, 1 not yet recruiting. 2 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 2 | Completed 1, Not yet recruiting 1 |
| Phase 2 | 1 | Not yet recruiting 1 |
Follow Severe Traumatic Brain Injury: new trials by email Literature Review of Severe Traumatic Brain Injury trials Research Report on Severe Traumatic Brain Injury
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Valproic AcId for Traumatic BRAin INjury Trial Valproic Acid (VPA), Standard of care treatment + normal saline - Moderate Traumatic Brain Injury (TBI), Severe Traumatic Brain Injury | Phase 2 / Phase 3 | Not yet recruiting | Northwestern University | 432 | 2027-05-01 | 2026-11-05 |
| Discrete Hypothermia in the Management of Traumatic Brain Injury CoolSystems Discrete Cerebral Hypothermia System - Severe Traumatic Brain Injury | Phase 3 | Completed | Emory University | 25 | 2006-07-01 | 2013-12-20 |
Brain Injuries, Traumatic (2) · Hypothermia (1) · Wounds and Injuries (1)
Brain Diseases (2) · Brain Injuries (2) · Central Nervous System Diseases (2) · Craniocerebral Trauma (2) · Nervous System Diseases (2) · Trauma, Nervous System (2) · Body Temperature Changes (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1) · Wounds and Injuries (1)
Saline Solution (1) · Valproic Acid (1)
Emory University (1) · Northwestern University (1)
United States (2)
Hasan Alam, MD (1) · Odette A Harris, MD, MPH (1)