3 completed, 3 unknown, 1 active not recruiting, 1 terminated. 9 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 3, Unknown 3, Active not recruiting 1, Terminated 1, Withdrawn 1 |
Follow Severe Aplastic Anemia: new trials by email Literature Review of Severe Aplastic Anemia trials Research Report on Severe Aplastic Anemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion CliniMACS - Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia in Remission | Not applicable | Active not recruiting | Baylor College of Medicine | 3 | 2023-12-06 | 2026-10-08 |
| A Study of PEG-rhG-CSF and rhG-CSF Used for Aplastic Anemia Granulocyte Deficiency PEG-rhG-CSF - Severe Aplastic Anemia | Not applicable | Unknown | Institute of Hematology & Blood Diseases Hospital, China | 45 | 2022-06-05 | 2022-09-26 |
| Efficacy and Safety of CSA and Avatrombopag for the Treatment of SAA in the Elderly Avatrombopag - Severe Aplastic Anemia | Not applicable | Unknown | Institute of Hematology & Blood Diseases Hospital, China | 80 | 2022-06-01 | 2022-06-27 |
| Haploidentical Transplantation in Severe Aplastic Anemia MSD-HSCT, HFD-HSCT - Severe Aplastic Anemia | Not applicable | Unknown | Wu Xiaoxiong | 60 | 2017-07-10 | 2017-08-11 |
| Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia cyclosporine, Matched Unrelated Donor Hematopoietic Stem Cell Transplant, horse anti-thymocyte globulin (ATG) - Severe Aplastic Anemia | Not applicable | Completed | Michael Pulsipher | 40 | 2016-08-01 | 2025-05-11 |
| Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation Alefacept - Thalassemia, Sickle Cell Disease | Not applicable | Terminated | Emory University | 3 | 2010-09-01 | 2017-07-27 |
| Reduced-Intensity Preparative Regimen for Allogeneic Stem Cell Transplantation in Patients With Severe Aplastic Anemia Cyclophosphamide, Fludarabine, Rabbit ATG - Severe Aplastic Anemia | Not applicable | Withdrawn | City of Hope Medical Center | 2009-11-01 | 2012-03-27 | |
| Unrelated Umbilical Cord Blood (UBC)Transplantation umbilical cord blood (UCB) - Chronic Myelogenous Leukemia (CML), Acute Myelogenous Leukemia (AML) | Not applicable | Completed | West Virginia University | 34 | 2009-02-03 | 2021-06-14 |
| Unrelated Donor Stem Cell Transplantation Allogeneic transplantation - Severe Aplastic Anemia, Paroxysmal Nocturnal Hemoglobinuria | Not applicable | Completed | Scripps Health | 64 | 2005-03-01 | 2022-11-23 |
Anemia, Aplastic (9) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (3) · Leukemia, Myeloid, Acute (3) · Lymphoma, Non-Hodgkin (3) · Myelodysplastic Syndromes (3) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (3) · Hodgkin Disease (2) · Leukemia, Lymphocytic, Chronic, B-Cell (2) · Multiple Myeloma (2) · Anemia (1) · Anemia, Diamond-Blackfan (1) · Anemia, Sickle Cell (1) · Bone Marrow Failure Disorders (1) · Chediak-Higashi Syndrome (1) · Cytopenia (1)
Bone Marrow Diseases (9) · Hematologic Diseases (9) · Hemic and Lymphatic Diseases (9) · Anemia (8) · Bone Marrow Failure Disorders (8) · Chronic Disease (4) · Disease Attributes (4) · Immune System Diseases (4) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Hemorrhagic Disorders (3) · Immunoproliferative Disorders (3) · Leukemia (3) · Leukemia, Lymphoid (3) · Leukemia, Myeloid (3)
Cyclophosphamide (2) · fludarabine (2) · thymoglobulin (2) · Alefacept (1) · Antilymphocyte Serum (1) · Cyclosporine (1) · Immunosuppression Therapy (1) · Methotrexate (1) · Transplantation, Homologous (1) · Whole-Body Irradiation (1) · avatrombopag (1) · pegylated granulocyte colony-stimulating factor (1)
Institute of Hematology & Blood Diseases Hospital, China (2) · Baylor College of Medicine (1) · City of Hope Medical Center (1) · Emory University (1) · Michael Pulsipher (1) · Scripps Health (1) · West Virginia University (1) · Wu Xiaoxiong (1)
United States (5) · China (3)
Anna Pawlowska, MD (1) · David A Williams, MD (1) · Erin Morales, MD (1) · Jeffrey W. Andrey, MD (1) · John Horan, MD (1) · Lei Ye, doctor (1) · Li Zhang, doctor (1) · Liping Jing, Doctor (1) · Michael Craig, MD (1) · Michael Pulsipher, MD (1) · Xiaoxiong WU, PhD (1)
PMID 18379007, PMID 21233311, PMID 26095669, PMID 28219216, PMID 28423296, PMID 30262561, PMID 30504345