5 completed, 4 recruiting, 2 active not recruiting, 2 not yet recruiting. 6 Phase 1, 5 Not applicable, 4 Phase 2.
Follow Sarcomas: new trials by email Literature Review of Sarcomas trials Research Report on Sarcomas
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effectiveness of 0.9% Normal Saline Soaking in Managing Acute Radiation Dermatitis Normal Saline Soaks (0.9% Sodium Chloride) - Acute Radiation Dermatitis, Head and Neck Cancer (H&N) | Not applicable | Not yet recruiting | King Hussein Cancer Center | 150 | 2026-05-01 | 2026-04-27 |
| BOLD-100 Plus Doxorubicin in Advanced Soft Tissue Sarcomas BOLD-100, Doxorubicin 75 mg/m^2 - Sarcoma, Soft-tissue, Sarcoma | Phase 1 | Not yet recruiting | University Health Network, Toronto | 32 | 2026-03-30 | 2025-12-01 |
| Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors ZL-6201 - Solid Tumors, Sarcomas | Phase 1 | Recruiting | Zai Lab (Shanghai) Co., Ltd. | 180 | 2026-03-02 | 2026-07-23 |
| Intrathecal Dexmedetomidine-Fentanyl Combination Versus Fentanyl Alone as Adjuvant to Bupivacaine in Spinal Anesthesia for Above Knee Amputation in Sarcomas of Lower Extremity Fentanyl + Dexmedetomidine, Fentanyl - Intrathecal, Dexmedetomidine | Not applicable | Recruiting | National Cancer Institute, Egypt | 58 | 2025-10-20 | 2025-12-11 |
| Cryopreserved Ovarian Tissue Transplantation in Patients Who Have Survived Sarcomas and Hematological Tumors Step 1, Step 2, Step 3 - Sarcomas, Haematological Malignancies | Not applicable | Recruiting | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 80 | 2024-08-12 | 2025-02-17 |
| Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas Cabozantinib - Ewing Sarcoma, Osteosarcoma | Phase 1 | Recruiting | Children's Hospital of Philadelphia | 30 | 2023-10-24 | 2026-09-03 |
| Aerosolized Azacytidine as Epigenetic Priming for Bintrafusp Alfa-Mediated Immune Checkpoint Blockade in Patients With Unresectable Pulmonary Metastases From Sarcomas, Germ Cell Tumors, or Epithelial Malignancies AeroEclipse II Breath Actuated Nebulizer, Bintrafusp alfa, Azacytidine - Sarcomas, Melanomas | Phase 1 / Phase 2 | Withdrawn | National Cancer Institute (NCI) | 2021-12-14 | 2021-12-17 | |
| Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC ONC-392, Pembrolizumab, Docetaxel - Non Small Cell Lung Cancer, Advanced Solid Tumor | Phase 1 / Phase 2 | Active not recruiting | OncoC4, Inc. | 733 | 2020-09-16 | 2026-09-14 |
| Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions) Entrectinib - Breast Cancer, Cholangiocarcinoma | Phase 2 | Active not recruiting | Hoffmann-La Roche | 534 | 2015-11-19 | 2026-08-25 |
| Dendritic Cell Vaccination for Patients with Solid Tumors autologous dendritic cell vaccination - Glioblastoma, Renal Cell Carcinoma | Phase 1 / Phase 2 | Completed | University Hospital, Antwerp | 48 | 2010-05-03 | 2024-12-09 |
| Blood and Tissue Study of Patients in NIH Protocol 08-C-0800 Sarcomas | Completed | National Cancer Institute (NCI) | 8 | 2008-12-09 | 2019-12-16 | |
| A Randomized Trial of The Effectiveness of Aromatherapy on Chemotherapy Induced Nausea and Vomiting in Children With Cancer Aromatherapy Scented Wand, Placebo wand - Brain Tumors, Leukemia | Not applicable | Completed | Albert Einstein College of Medicine | 132 | 2008-07-01 | 2018-09-07 |
| Open Label Trial of Perifosine in Patients Currently Being Treated on Perifosine Trials in Solid Tumors or Multiple Myeloma Perifosine, Trastuzumab, Tamoxifen - Non Small Cell Lung Cancer, Solid Tumors | Not applicable | Completed | AEterna Zentaris | 10 | 2008-05-01 | 2018-03-15 |
| An Adequate Cost Effective Follow Up Protocol For Bone and Soft Tissue Sarcomas Sarcomas | Completed | Tata Memorial Hospital | 500 | 2006-01-01 | 2023-04-25 |
Sarcoma (14) · Breast Neoplasms (4) · Carcinoma, Renal Cell (4) · Carcinoma, Non-Small-Cell Lung (3) · Colorectal Neoplasms (3) · Melanoma (3) · Brain Neoplasms (2) · Head and Neck Neoplasms (2) · Osteosarcoma (2) · Ovarian Neoplasms (2) · Pancreatic Neoplasms (2) · Salivary Gland Neoplasms (2) · Sarcoma, Ewing (2) · Bone Neoplasms (1) · Carcinoma, Adenoid Cystic (1)
Neoplasms by Histologic Type (14) · Neoplasms, Connective and Soft Tissue (14) · Neoplasms (13) · Neoplasms by Site (8) · Skin and Connective Tissue Diseases (6) · Neoplasms, Glandular and Epithelial (5) · Neoplasms, Nerve Tissue (5) · Neuroectodermal Tumors (5) · Skin Diseases (5) · Adenocarcinoma (4) · Breast Diseases (4) · Carcinoma (4) · Female Urogenital Diseases (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Kidney Diseases (4)
Aromatherapy (1) · Azacitidine (1) · Dexmedetomidine (1) · Docetaxel (1) · Doxorubicin (1) · Fentanyl (1) · KP 1339 (1) · SE 1-step Futurabond M (1) · Sodium Chloride (1) · Tamoxifen (1) · Trastuzumab (1) · bintrafusp alfa protein, human (1) · cabozantinib (1) · entrectinib (1) · pembrolizumab (1)
National Cancer Institute (NCI) (2) · AEterna Zentaris (1) · Albert Einstein College of Medicine (1) · Children's Hospital of Philadelphia (1) · Hoffmann-La Roche (1) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (1) · King Hussein Cancer Center (1) · National Cancer Institute, Egypt (1) · OncoC4, Inc. (1) · Tata Memorial Hospital (1) · University Health Network, Toronto (1) · University Hospital, Antwerp (1) · Zai Lab (Shanghai) Co., Ltd. (1)
United States (7) · Australia (2) · Belgium (2) · China (2) · Italy (2) · Canada (1) · Egypt (1) · France (1) · Germany (1) · Hong Kong (1) · India (1) · Japan (1) · Jordan (1) · Netherlands (1) · Poland (1)
David S Schrump, M.D. (1) · Eric Grossman, MD (1) · Karen Moody, MD, MS (1) · Lee J Helman, M.D. (1) · Renato Seracchioli, MD (1) · Theodore Laetsch, MD (1) · Tianhong Li, MD (1)
PMID 29118225, PMID 31838007, PMID 31838015, PMID 33646820, PMID 34427452, PMID 34924145, PMID 36924196, PMID 38848521, PMID 39549678, PMID 40086048, PMID 40341199
2015 (1), R44CA250824 (1)