5 recruiting, 2 completed, 2 terminated, 2 unknown. 5 Phase 2, 2 Not applicable, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Recruiting 4, Unknown 1 |
| Not applicable | 2 | Completed 1, Unknown 1 |
| Phase 1 | 2 | Active not recruiting 1, Recruiting 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Sarcoma of Bone: new trials by email Literature Review of Sarcoma of Bone trials Research Report on Sarcoma of Bone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sequential Infusion of CD146-Targeted and HER2-Targeted CAR T Cells in Patients With Advanced Sarcomas CD146/HER2 CAR-T cells - Sarcoma, Sarcoma, Kaposi | Phase 1 / Phase 2 | Recruiting | Essen Biotech | 60 | 2025-05-29 | 2025-07-15 |
| XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma, Bone Sarcoma or Translocation-associated Soft Tissue Sarcoma Biospecimen Collection, Computed Tomography, Echocardiography - Metastatic Leiomyosarcoma, Unresectable Leiomyosarcoma | Phase 2 | Recruiting | Northwestern University | 73 | 2024-09-19 | 2026-10-13 |
| Phase II Clinical Trial of Chidamide Combined With AK112 for Second-line and Advanced Bone and Soft Tissue Sarcoma Chidamide Tablets combined with AK112 - Sarcoma,Soft Tissue, Sarcoma | Phase 2 | Recruiting | Shanxi Province Cancer Hospital | 30 | 2024-08-01 | 2024-10-15 |
| PARP Inhibition, Stereotactic Body Radiotherapy and Immunotherapy for Metastatic or Advanced Sarcoma (PRIMA) Camrelizumab and fluzoparib with concurrent stereotactic body radiotherapy (SBRT) - Sarcoma, Sarcoma,Soft Tissue | Phase 2 | Recruiting | Ruijin Hospital | 86 | 2023-06-01 | 2023-10-31 |
| In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors Anti-CD40 Agonist Monoclonal Antibody CDX-1140, Poly ICLC, Radiation Therapy - Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma | Phase 1 | Active not recruiting | University of Southern California | 14 | 2023-01-09 | 2026-06-18 |
| 3D Printed Implants for the Defect Reconstruction in Patients With Chest Wall Tumors Implants, Plates - Tumor of Bone, Chest Wall Tumor | Not applicable | Unknown | Blokhin's Russian Cancer Research Center | 30 | 2022-01-10 | 2024-04-01 |
| Neoadjuvant Combination of Doxorubicin, Cisplatin and Methotrexate in Patients Aged 24-40 Years With Primary Bone Tumors Doxorubicin, Cisplatin, Methotrexate, Doxorubicin, Cisplatin - Osteosarcoma, Neoplasms, Connective Tissue | Phase 2 / Phase 3 | Unknown | Blokhin's Russian Cancer Research Center | 50 | 2022-01-10 | 2024-04-01 |
| GISAR German Interdisciplinary Sarcoma Registry Sarcoma, Sarcoma,Soft Tissue | Recruiting | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | 9000 | 2018-11-29 | 2026-02-05 | |
| Retrospective Study in Sarcoma Patients Sarcoma of Bone, Sarcoma of Soft Tissue | Completed | University Medicine Greifswald | 514 | 2017-04-18 | 2021-11-15 | |
| National Swiss Sarcoma Cohort Study Registration - Sarcoma, Neoplasm of Bone | Terminated | Balgrist University Hospital | 50 | 2015-04-01 | 2018-10-02 | |
| Exercise Rehabilitation to Improve Long-term Outcomes in Sarcoma Survivors. Supervised Exercise Rehabilitation Program - Sarcoma, Sarcoma of Bone and Connective Tissue | Not applicable | Completed | Curtin University | 25 | 2014-01-01 | 2026-10-23 |
| Identification and Characterization of Molecular Markers in Musculoskeletal Tumors Identification and characterization of molecular markers in musculoskeletal tumors - Soft Tissue and Bone Tumors, Sarcoma | Terminated | Balgrist University Hospital | 50 | 2010-01-01 | 2018-10-02 |
Osteosarcoma (12) · Sarcoma (10) · Bone Neoplasms (6) · Sarcoma, Ewing (2) · Sarcoma, Synovial (2) · Breast Neoplasms (1) · Carcinoma, Basal Cell (1) · Carcinoma, Merkel Cell (1) · Carcinosarcoma (1) · Leiomyosarcoma (1) · Lymphoma (1) · Melanoma (1) · Neoplasms (1) · Neoplasms, Connective Tissue (1) · Neoplasms, Connective and Soft Tissue (1)
Neoplasms by Histologic Type (12) · Neoplasms, Bone Tissue (12) · Neoplasms (11) · Neoplasms, Connective Tissue (11) · Neoplasms, Connective and Soft Tissue (11) · Bone Diseases (6) · Musculoskeletal Diseases (6) · Neoplasms by Site (6) · DNA Virus Infections (2) · Infections (2) · Sarcoma (2) · Skin and Connective Tissue Diseases (2) · Virus Diseases (2) · Adenocarcinoma (1) · Breast Diseases (1)
Bone Plates (1) · Cisplatin (1) · Doxorubicin (1) · Methotrexate (1) · N-(2-amino-5-fluorobenzyl)-4-(N-(pyridine-3-acrylyl)aminomethyl)benzamide (1) · Radiation (1) · Radiotherapy (1) · Specimen Handling (1) · camrelizumab (1) · flt3 ligand protein (1) · fluzoparib (1) · pembrolizumab (1) · poly ICLC (1) · tocilizumab (1)
Balgrist University Hospital (2) · Blokhin's Russian Cancer Research Center (2) · Curtin University (1) · Essen Biotech (1) · Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest (1) · Northwestern University (1) · Ruijin Hospital (1) · Shanxi Province Cancer Hospital (1) · University Medicine Greifswald (1) · University of Southern California (1)
China (3) · Germany (2) · Russia (2) · Switzerland (2) · United States (2)
Aslan Valiev, PhD (1) · Beniamin Bokhyan, PhD (1) · Bruno Fuchs, MD PhD (1) · Daniel Pink, MD (1) · Fumito Ito, MD (1) · Junxiang Wen, PhD, MD (1) · Pavel Kononets, PhD (1) · Pedro Hermida de Viveiros, MD (1) · Peter Reichardt, MD (1) · Qiyuan Bao, PhD, MD (1) · Salah-Eddin Al-Batran, Prof. Dr (1) · Weibin Zhang, PhD, MD (1) · Xin Wang (1) · Yuhui Shen, PhD, MD (1)
P30CA060553 (1)