13 completed, 3 unknown, 2 not yet recruiting, 2 recruiting. 5 Phase 2, 3 Not applicable, 3 Phase 3, 2 Phase 1, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 4, Withdrawn 1 |
| Not applicable | 3 | Completed 2, Not yet recruiting 1 |
| Phase 3 | 3 | Completed 2, Terminated 1 |
| Phase 1 | 2 | Completed 1, Withdrawn 1 |
| Early Phase 1 | 1 | Active not recruiting 1 |
Follow Rhinovirus: new trials by email Literature Review of Rhinovirus trials Research Report on Rhinovirus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ELderly REspiratory VIral Cohort Respiratory viral infection - Influenza Viruses, Respiratory Syncytial Virus (RSV) | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 1000 | 2026-10-01 | 2026-09-10 | |
| The Rhinovirus Hospitalization and Investigation of Nasal-airway Omics (RHINO) Study Nasal Swab Healthy Surveillance, Nasal Swab Sick Samples, Nasal Swab Hospitalized Cohort - Rhinovirus | Recruiting | University of Wisconsin, Madison | 670 | 2026-08-04 | 2026-08-10 | |
| A Study of APL-10456-Vaccine APL-10456-Vaccine, Placebo - Rhinovirus | Early Phase 1 | Active not recruiting | Apollo Therapeutics Ltd | 144 | 2026-02-16 | 2026-05-27 |
| Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective Dengue, Chikungunya | Recruiting | Institut Pasteur du Cambodge | 10000 | 2025-12-18 | 2026-01-22 | |
| Clinical Validation of the Aptitude Medical Systems Metrix Respiratory Panel Test in At-Home/Non-Laboratory Settings Aptitude Medical Systems Respiratory Panel Test - COVID -19, Influenza A | Not applicable | Not yet recruiting | Aptitude Medical Systems | 2000 | 2025-11-01 | 2025-10-16 |
| Study of Airway Inflammatory Responses to Experimental Rhinovirus Infection RG-HRV16 - Healthy Volunteers, Rhinovirus | Phase 1 | Withdrawn | University of North Carolina, Chapel Hill | 2024-12-01 | 2025-06-03 | |
| RCT of Vapendavir in Patients With COPD and Human Rhinovirus/Enterovirus Upper Respiratory Infection Vapendavir, Placebo - COPD Exacerbation Acute, COPD With Acute Lower Respiratory Infection | Phase 2 | Completed | Altesa Biosciences, Inc. | 52 | 2023-11-20 | 2025-09-30 |
| Impact of the Covid-19 on RSV Epidemic in the Metropolis of Lyon epidemiology - Rhinovirus, RSV Infection in Children Less Than 5 Years of Age | Unknown | Hospices Civils de Lyon | 600 | 2022-06-01 | 2022-04-27 | |
| Impact of Covid-19 on Rhinovirus Epidemic epidemiology - Rhinovirus | Unknown | Hospices Civils de Lyon | 400 | 2022-05-01 | 2022-04-27 | |
| Impact of the Covid-19 on RSV epidemiology - Rhinovirus, RSV Infection | Unknown | Hospices Civils de Lyon | 600 | 2022-05-01 | 2022-05-03 | |
| First-in-human Clinical Trial Evaluating CUR-N399 in Healthy Volunteers. CUR-N399, Placebo - Pulmonary Disease, Chronic Obstructive, Enterovirus Infections | Phase 1 | Completed | Curovir AB | 74 | 2021-07-22 | 2022-03-23 |
| Biomarkers in Nasal Samples of Seasonal Allergic Rhinitics Seasonal Allergic Rhinitis, Rhinovirus | Completed | University of North Carolina, Chapel Hill | 92 | 2021-03-22 | 2023-05-17 | |
| Trial to Evaluate Efficacy and Safety of Nitazoxanide in the Treatment of Colds Due to Enterovirus/Rhinovirus Infection Nitazoxanide, Placebo, Vitamin Super B-Complex - Enterovirus, Rhinovirus | Phase 3 | Terminated | Romark Laboratories L.C. | 214 | 2020-08-19 | 2024-10-17 |
| Efficacy and Safety of Nitazoxanide in the Treatment of Colds Due to Enterovirus/Rhinovirus Infection Nitazoxanide, Placebo - Enterovirus, Rhinovirus | Phase 3 | Completed | Romark Laboratories L.C. | 1756 | 2018-09-11 | 2022-04-14 |
| Specific Respiratory Infections as Triggers of Acute Medical Events Influenza, Human, Respiratory Syncytial Virus Infections | Completed | University College, London | 787000 | 2016-09-01 | 2017-05-04 | |
| 'The Impact of Rhinovirus Infections in Paediatric Cardiac Surgery' rhinovirus diagnostics - Rhinovirus, Congenital Heart Disease | Completed | Leiden University | 166 | 2015-06-01 | 2020-09-25 | |
| Effect of OC459 on the Response to Rhinovirus Challenge in Asthma OC459, Placebo, Rhinovirus - Asthma, Rhinovirus | Phase 2 | Completed | Imperial College London | 44 | 2015-01-01 | 2021-02-26 |
| Discovering New Treatments for Asthma and COPD. A New Human Rhinvovirus for Human Challenge Titre 1, Titre 2, Titre 3 - Rhinovirus | Not applicable | Completed | Hvivo | 17 | 2013-01-01 | 2015-08-13 |
| Collection and Testing of Respiratory Samples artus Influenza A/B RT-PCR Test - QIAGEN ResPlex II Advanced Panel, Influenza A | Completed | QIAGEN Gaithersburg, Inc | 272 | 2011-02-01 | 2017-05-10 | |
| The Respiratory Protection Effectiveness Clinical Trial N95 Respirator, Medical/surgical mask - Influenza, Respiratory Syncytial Viruses | Not applicable | Completed | Johns Hopkins University | 2862 | 2010-12-01 | 2019-04-25 |
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Asthma (5) · Enterovirus Infections (5) · Adenoviridae Infections (4) · Respiratory Tract Infections (4) · Bronchiolitis (3) · Common Cold (3) · Coronavirus Infections (3) · Influenza, Human (3) · Paramyxoviridae Infections (3) · Pneumonia (3) · Respiratory Syncytial Virus Infections (3) · Infections (2) · Meningitis (2) · Picornaviridae Infections (2) · Pulmonary Disease, Chronic Obstructive (2)
Infections (16) · Respiratory Tract Diseases (15) · RNA Virus Infections (12) · Virus Diseases (12) · Respiratory Tract Infections (10) · Lung Diseases (7) · Hypersensitivity (6) · Hypersensitivity, Immediate (6) · Immune System Diseases (6) · Lung Diseases, Obstructive (6) · Picornaviridae Infections (6) · Respiratory Hypersensitivity (6) · Bronchial Diseases (5) · Mononegavirales Infections (5) · Coronaviridae Infections (4)
nitazoxanide (2) · (5-fluoro-2-methyl-3-quinolin-2-ylmethylindo-1-yl)acetic acid (1) · Cholecalciferol (1) · Glucose (1) · N95 Respirators (1) · Peak Expiratory Flow Rate (1) · Saline Solution, Hypertonic (1) · Sucrose (1) · pleconaril (1)
Hospices Civils de Lyon (3) · Romark Laboratories L.C. (2) · University of North Carolina, Chapel Hill (2) · Altesa Biosciences, Inc. (1) · Apollo Therapeutics Ltd (1) · Aptitude Medical Systems (1) · Assistance Publique - Hôpitaux de Paris (1) · Biota Scientific Management Pty Ltd (1) · Curovir AB (1) · Hvivo (1) · Imperial College London (1) · Institut Pasteur du Cambodge (1) · Johns Hopkins University (1) · Leiden University (1) · Merck Sharp & Dohme LLC (1)
United States (9) · United Kingdom (3) · France (2) · Australia (1) · Cambodia (1) · Canada (1) · Netherlands (1) · Puerto Rico (1) · Sweden (1)
Anna Novotney-Barry (1) · Anneloes L Klink, Msc (1) · Brad W Killingsworth, M.A. (1) · Bryan Murray, MD (1) · Charlotte Gaydos, PhD (1) · Charlotte MJ Warren-Gash, MRCP PhD (1) · Claude Flamand, Ph.D. (1) · Connie S Price, MD (1) · Derek Cummings, PhD (1) · Ellen R Wald, MD (1) · Jean-Francois Rossignol, M.D., Ph.D (1) · John Lambert, PhD (1) · Lewis Radonovich, MD (1) · Marek Smieja, MD, MSc, PhD, FRCPC (1) · Michael Simberkoff, MD (1)
PMID 33215698, PMID 36715243, PMID 22558168, PMID 24885201, PMID 25830416, PMID 27936016, PMID 29324996, PMID 31479137, PMID 32645144, PMID 33027243, PMID 33581146, PMID 38713818, PMID 39674537, PMID 39674538
R01AI182200 (1)