16 completed, 6 unknown, 1 recruiting, 1 terminated. 9 Phase 2, 4 Phase 3, 3 Not applicable, 3 Phase 4, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 7, Unknown 2 |
| Phase 3 | 4 | Completed 3, Unknown 1 |
| Not applicable | 3 | Completed 1, Recruiting 1, Terminated 1 |
| Phase 4 | 3 | Completed 2, Unknown 1 |
| Phase 1 | 2 | Completed 2 |
Follow Retinal Neovascularization: new trials by email Literature Review of Retinal Neovascularization trials Research Report on Retinal Neovascularization
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Artificial Intelligence-Assisted Lesion-Based Urgent Referral Triage of Ultra-Widefield Retinal Images AI-Assisted UWF Lesion-Based Triage System, Unassisted Interpretation - Vision-Threatening Retinal Lesions, Urgent Referral Retinal Findings | Not applicable | Completed | Xiamen Ophthalmology Center Affiliated to Xiamen University | 11 | 2026-07-01 | 2026-09-22 |
| Early Vitrectomy vs PRP in Early Proliferative Diabetic Retinopathy Microincision Vitrectomy Surgery, Panretinal Photocoagulation - Proliferative Diabetic Retinopathy (PDR) | Not applicable | Recruiting | Xiamen Ophthalmology Center Affiliated to Xiamen University | 100 | 2025-01-01 | 2026-05-14 |
| Home OCT Guided Management Study of Subjects Diagnosed With Neovascular-AMD Retinal Neovascularization | Unknown | Notal Vision Inc. | 15 | 2022-09-09 | 2023-05-22 | |
| High Resolution Optical Coherence Tomography High-resolution optical coherence tomography (High-Res-OCT), Standard spectral domain OCT (SD-OCT) - Retinal Disease, Retinal Detachment | Unknown | Insel Gruppe AG, University Hospital Bern | 550 | 2021-11-30 | 2022-11-29 | |
| Efficacy and Safety of Intravitreal Injection of Bevacizumab with and Without Oral Curcumin bevacizumab with oral curcumin, bevacizumab with oral placebo - Diabetic Macular Edema, Macular Edema | Phase 2 / Phase 3 | Unknown | Isfahan University of Medical Sciences | 52 | 2021-10-10 | 2024-09-19 |
| Daily Testing at Home by NV-AMD Subjects With Notal Home OCT. Retinal Neovascularization | Completed | Notal Vision Inc. | 15 | 2020-12-08 | 2021-11-29 | |
| Study of Efficacy and Safety of Brolucizumab Versus Panretinal Photocoagulation Laser in Patients With Proliferative Diabetic Retinopathy Brolucizumab 6 mg, Panretinal photocoagulation laser - Proliferative Diabetic Retinopathy | Phase 3 | Completed | Novartis Pharmaceuticals | 689 | 2020-11-19 | 2025-10-16 |
| Feasibility Study and Preliminary Application Study on Iris OCTA OCTA (ZEISS) - Conjunctivitis, Glaucoma | Unknown | Shanghai Eye Disease Prevention and Treatment Center | 4000 | 2018-10-01 | 2018-09-06 | |
| Study of the Modification of the Retinal Nerve Fiber Layer in Patients Treated With Intravitreous Injection of Anti-VEGF Gonioscopy - Retinal Neovascularization | Completed | Fondation Ophtalmologique Adolphe de Rothschild | 74 | 2016-07-01 | 2021-08-03 | |
| Safety and Efficacy of Propranolol 0.2% Eye Drops in Treating Retinopathy of Premature: A Pilot Study (DROP-ROP-0.2%) Propranolol 0.2% eye drops - Retinopathy of Prematurity | Phase 2 | Completed | Meyer Children's Hospital IRCCS | 98 | 2015-07-01 | 2018-08-31 |
| Ziv-aflibercept in Ocular Disease Requiring Anti-VEGF Injection ziv-aflibercept - Neovascularization, Macular Degeneration | Phase 2 | Unknown | Rafic Hariri University Hospital | 100 | 2015-03-01 | 2018-08-29 |
| Longterm Efficiency and Safety of Intravitreal Injections With Bevacizumab in Patients With Neovascularisation or Macular Edema Bevacizumab Injection [Avastin] - Retinal Neovascularization, Macular Edema | Phase 4 | Completed | University Hospital, Ghent | 583 | 2013-11-22 | 2026-09-21 |
| Safety and Efficacy of Propranolol Eye Drops in Treating Retinopathy of Premature Propranolol eye drops - Retinopathy of Prematurity | Phase 2 | Completed | Meyer Children's Hospital IRCCS | 23 | 2013-11-01 | 2015-07-07 |
| Squalamine for the Treatment in Proliferative Diabetic Retinopathy Squalamine Lactate ophthalmic solution 0.2% - Retinal Neovascularization | Phase 2 | Completed | Elman Retina Group | 6 | 2013-02-01 | 2015-02-10 |
| PASCAL Laser Versus ETDRS Laser Associated With Intravitreal Ranibizumab (IVR) Versus Only IVR for Proliferative Diabetic Retinopathy Intravitreal Ranibizumabe, panfotocoagulation (PASCAL), panfotocoagulation (PRP) single shoot (ETDRS) - Proliferative Diabetic Retinopathy | Phase 4 | Unknown | University of Sao Paulo | 31 | 2012-02-01 | 2013-12-09 |
| Safety and Efficacy Study of rAAV.sFlt-1 in Patients With Exudative Age-Related Macular Degeneration rAAV.sFlt-1, Control (ranibizumab alone) - Macular Degeneration, Age-related Maculopathies | Phase 1 / Phase 2 | Completed | Lions Eye Institute, Perth, Western Australia | 40 | 2011-12-01 | 2017-09-01 |
| Ranibizumab in Diabetic Vitrectomy. A Prospective, Randomised Controlled Trial of Ranibizumab Pre-treatment in Diabetic Vitrectomy - a Pilot Study Ranibizumab, Saline - Diabetic Retinopathy, Retinal Neovascularisation | Phase 4 | Completed | Moorfields Eye Hospital NHS Foundation Trust | 30 | 2011-03-30 | 2020-09-09 |
| Selective Retinal Pigment Epithelium Laser Therapy for Macular Disease of the Retina Selective retinal pigment epithelium laser therapy using the R:GEN Laser System - Macular Edema, Central Serous Chorioretinopathy | Not applicable | Terminated | Insel Gruppe AG, University Hospital Bern | 18 | 2010-06-01 | 2023-02-09 |
| Safety and Tolerability Study of AAV2-sFLT01 in Patients With Neovascular Age-Related Macular Degeneration (AMD) AAV2-sFLT01 - Macular Degeneration, Age-Related Maculopathies | Phase 1 | Completed | Genzyme, a Sanofi Company | 19 | 2010-01-11 | 2018-08-22 |
| Panretinal Photocoagulation (PRP) Plus Ranibizumab for Proliferative Diabetic Retinopathy Ranibizumab, Panretinal Photocoagulation - Diabetic Retinopathy, Retinal Neovascularization | Phase 2 | Completed | University of Sao Paulo | 40 | 2009-02-01 | 2011-08-04 |
Showing 20 of 24. Sign in to see all of them.
Diabetic Retinopathy (8) · Macular Edema (6) · Macular Degeneration (5) · Retinal Vein Occlusion (4) · Retinal Detachment (3) · Retinal Diseases (3) · Diabetes Mellitus (2) · Eye Diseases (2) · Glaucoma (2) · Retinal Degeneration (2) · Retinopathy of Prematurity (2) · Uveitis (2) · Central Serous Chorioretinopathy (1) · Choroidal Neovascularization (1)
Metaplasia (24) · Pathologic Processes (24) · Pathological Conditions, Signs and Symptoms (24) · Neovascularization, Pathologic (23) · Eye Diseases (22) · Retinal Diseases (21) · Cardiovascular Diseases (10) · Vascular Diseases (10) · Diabetic Angiopathies (8) · Endocrine System Diseases (8) · Diabetes Complications (7) · Diabetes Mellitus (6) · Retinal Degeneration (6) · Embolism and Thrombosis (4) · Thrombosis (4)
Bevacizumab (3) · Ranibizumab (3) · Curcumin (1) · Gonioscopy (1) · Ophthalmic Solutions (1) · Propranolol (1) · Sodium Chloride (1) · Triamcinolone (1) · aflibercept (1) · brolucizumab (1)
University of Sao Paulo (3) · Insel Gruppe AG, University Hospital Bern (2) · Meyer Children's Hospital IRCCS (2) · Notal Vision Inc. (2) · Xiamen Ophthalmology Center Affiliated to Xiamen University (2) · Elman Retina Group (1) · Fondation Ophtalmologique Adolphe de Rothschild (1) · Genzyme, a Sanofi Company (1) · Isfahan University of Medical Sciences (1) · Lions Eye Institute, Perth, Western Australia (1) · Moorfields Eye Hospital NHS Foundation Trust (1) · National Eye Institute (NEI) (1) · Novartis Pharmaceuticals (1) · Ophthalmological Association Edelweiss (1) · Rafic Hariri University Hospital (1)
United States (5) · Brazil (4) · China (3) · Australia (2) · Iran (2) · Italy (2) · Switzerland (2) · Argentina (1) · Belgium (1) · Canada (1) · Chile (1) · France (1) · India (1) · Japan (1) · Lebanon (1)
Jeff Heier, MD (2) · Luca Filippi, MD (2) · Ahmad M Mansour, MD (1) · Alireza Ramezani, MD (1) · Andreas Ebneter (1) · Ian Constable, Professor (1) · James W Bainbridge, MA PhD FRCOphth (1) · Nancy Holekamp, MD (1) · Otacilio O Maia Jr, M.D. (1) · Oussama Habra, MD (1) · Sebastian Wolf (1) · Walter Y Takahashi, M.D. (1)
PMID 39207600, PMID 17659962, PMID 25677668, PMID 26431823, PMID 27030277, PMID 27814346, PMID 27865764, PMID 28526489, PMID 28614154, PMID 28709412, PMID 28974567, PMID 31134171, PMID 31956432, PMID 33470281, PMID 34781913, PMID 37260074, PMID 38308203, PMID 39287534, PMID 42024409