7 completed, 2 unknown. 9 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 7, Unknown 2 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Retinal Neovascularization: new trials by email Literature Review of Retinal Neovascularization trials Research Report on Retinal Neovascularization
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Intravitreal Injection of Bevacizumab with and Without Oral Curcumin bevacizumab with oral curcumin, bevacizumab with oral placebo - Diabetic Macular Edema, Macular Edema | Phase 2 / Phase 3 | Unknown | Isfahan University of Medical Sciences | 52 | 2021-10-10 | 2024-09-19 |
| Safety and Efficacy of Propranolol 0.2% Eye Drops in Treating Retinopathy of Premature: A Pilot Study (DROP-ROP-0.2%) Propranolol 0.2% eye drops - Retinopathy of Prematurity | Phase 2 | Completed | Meyer Children's Hospital IRCCS | 98 | 2015-07-01 | 2018-08-31 |
| Ziv-aflibercept in Ocular Disease Requiring Anti-VEGF Injection ziv-aflibercept - Neovascularization, Macular Degeneration | Phase 2 | Unknown | Rafic Hariri University Hospital | 100 | 2015-03-01 | 2018-08-29 |
| Safety and Efficacy of Propranolol Eye Drops in Treating Retinopathy of Premature Propranolol eye drops - Retinopathy of Prematurity | Phase 2 | Completed | Meyer Children's Hospital IRCCS | 23 | 2013-11-01 | 2015-07-07 |
| Squalamine for the Treatment in Proliferative Diabetic Retinopathy Squalamine Lactate ophthalmic solution 0.2% - Retinal Neovascularization | Phase 2 | Completed | Elman Retina Group | 6 | 2013-02-01 | 2015-02-10 |
| Safety and Efficacy Study of rAAV.sFlt-1 in Patients With Exudative Age-Related Macular Degeneration rAAV.sFlt-1, Control (ranibizumab alone) - Macular Degeneration, Age-related Maculopathies | Phase 1 / Phase 2 | Completed | Lions Eye Institute, Perth, Western Australia | 40 | 2011-12-01 | 2017-09-01 |
| Panretinal Photocoagulation (PRP) Plus Ranibizumab for Proliferative Diabetic Retinopathy Ranibizumab, Panretinal Photocoagulation - Diabetic Retinopathy, Retinal Neovascularization | Phase 2 | Completed | University of Sao Paulo | 40 | 2009-02-01 | 2011-08-04 |
| Intravitreal Avastin in Proliferative Retinopathies Avastin - Retinal Neovascularization | Phase 2 | Completed | Ophthalmological Association Edelweiss | 100 | 2007-07-01 | 2011-07-22 |
| Intravitreal Triamcinolone for Acute Branch Retinal Vein Occlusion Triamcinolone - Branch Retinal Vein Occlusion | Phase 2 | Completed | Shahid Beheshti University of Medical Sciences | 30 | 2003-02-01 | 2008-06-17 |
Diabetic Retinopathy (3) · Macular Edema (3) · Macular Degeneration (2) · Retinal Vein Occlusion (2) · Retinopathy of Prematurity (2) · Choroidal Neovascularization (1) · Eye Diseases (1) · Neovascularization, Pathologic (1) · Pterygium (1) · Retinal Degeneration (1) · Retinal Diseases (1) · Wet Macular Degeneration (1)
Metaplasia (9) · Pathologic Processes (9) · Pathological Conditions, Signs and Symptoms (9) · Eye Diseases (8) · Neovascularization, Pathologic (8) · Retinal Diseases (8) · Cardiovascular Diseases (4) · Vascular Diseases (4) · Diabetes Complications (3) · Diabetes Mellitus (3) · Diabetic Angiopathies (3) · Endocrine System Diseases (3) · Retinal Degeneration (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Embolism and Thrombosis (2)
Bevacizumab (2) · Ranibizumab (2) · Curcumin (1) · Ophthalmic Solutions (1) · Propranolol (1) · Triamcinolone (1) · aflibercept (1)
Meyer Children's Hospital IRCCS (2) · Elman Retina Group (1) · Isfahan University of Medical Sciences (1) · Lions Eye Institute, Perth, Western Australia (1) · Ophthalmological Association Edelweiss (1) · Rafic Hariri University Hospital (1) · Shahid Beheshti University of Medical Sciences (1) · University of Sao Paulo (1)
Iran (2) · Italy (2) · Australia (1) · Brazil (1) · Lebanon (1) · Romania (1) · United States (1)
Luca Filippi, MD (2) · Ahmad M Mansour, MD (1) · Alireza Ramezani, MD (1) · Ian Constable, Professor (1)
PMID 25677668, PMID 26431823, PMID 27030277, PMID 27814346, PMID 27865764, PMID 28614154, PMID 28709412, PMID 31134171, PMID 31956432, PMID 39207600