9 withdrawn. 9 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Withdrawn 9 |
| Phase 2 | 3 | Withdrawn 3 |
Follow Retinal Degeneration: new trials by email Literature Review of Retinal Degeneration trials Research Report on Retinal Degeneration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Brolucizumab 6mg in a Treat and Extend Regimen in Patients With Neovascular Age-Related Macular Degeneration (nAMD) With Prior Anti-VEGF Exposure (PEREGRINE) brolucizumab - Age-related Macular Degeneration (AMD) | Phase 3 | Withdrawn | Novartis Pharmaceuticals | 2021-05-31 | 2021-09-23 | |
| Laser vs Bevacizumab Injection Alone in Treatment of Diabetic Macular Edema bevacizumab, PASCAL Endpoint Management (EpM) laser treatment - Diabetic Macular Edema | Phase 2 / Phase 3 | Withdrawn | University of California, San Francisco | 2021-01-01 | 2020-07-31 | |
| Combined Ranibizumab and Iluvien for Diabetic Macular Oedema Iluvien 0.19 MG Drug Implant, Ranibizumab Injection [Lucentis], Sham Intravitreal Injection - Diabetic Macular Edema, Diabetes | Phase 2 / Phase 3 | Withdrawn | Imperial College London | 2019-09-01 | 2023-10-02 | |
| Safety & Efficacy Study Evaluating the Combination of Bevasiranib & Lucentis Therapy in Wet AMD (CARBON) Bevasiranib, ranibizumab - Age Related Macular Degeneration | Phase 3 | Withdrawn | OPKO Health, Inc. | 2009-11-01 | 2015-03-06 | |
| Intravitreal Bevacizumab (Avastin) for Pseudophakic Macular Edema (PME) Bevacizumab - Cystoid Macular Edema | Phase 3 | Withdrawn | Asociación para Evitar la Ceguera en México | 2006-11-01 | 2024-06-05 | |
| The Avastin vs Visudyne for Neovascular AMD Study Bevacizumab (Avastin), Verteporfin photodynamic therapy (PDT) - Age-related Macular Degeneration | Phase 3 | Withdrawn | St. Erik Eye Hospital | 2006-11-01 | 2024-01-31 | |
| Bevacizumab and Retinal Vascular Occlusions Intravitreal injection - Edema Macular, Vascular Occlusion | Phase 3 | Withdrawn | Asociación para Evitar la Ceguera en México | 2006-06-01 | 2024-06-03 | |
| Comparative Study With Photodynamic Therapy And Triamcinolone Versus Photodynamic Therapy, Triamcinolone And Ranibizumab In Patients With Subfoveal Choroidal Neovascularization intravitreal injection of ranibizumab, intravitreal injection of triamcinolone, photodynamic therapy - Subfoveal Choroidal Neovascularization | Phase 2 / Phase 3 | Withdrawn | Asociación para Evitar la Ceguera en México | 2006-04-01 | 2024-05-30 | |
| Safety and Efficacy Study of BCD-021 Compared to Lucentis® in Patients With Neovascular Wet Age-related Macular Degeneration Bevacizumab, Ranibizumab - Wet Age-related Macular Degeneration | Phase 3 | Withdrawn | Biocad | 2016-03-31 |
Macular Degeneration (5) · Macular Edema (4) · Choroidal Neovascularization (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 1 (1) · Diabetes Mellitus, Type 2 (1) · Diabetic Retinopathy (1) · Eye Diseases (1) · Geographic Atrophy (1) · Wet Macular Degeneration (1)
Retinal Diseases (9) · Eye Diseases (8) · Macular Degeneration (4) · Endocrine System Diseases (2) · Glucose Metabolism Disorders (2) · Metabolic Diseases (2) · Nutritional and Metabolic Diseases (2) · Autoimmune Diseases (1) · Cardiovascular Diseases (1) · Choroid Diseases (1) · Diabetes Complications (1) · Diabetes Mellitus (1) · Diabetic Angiopathies (1) · Immune System Diseases (1)
Bevacizumab (4) · Ranibizumab (3) · Drug Implants (1) · Fluocinolone Acetonide (1) · Intravitreal Injections (1) · Photochemotherapy (1) · bevasiranib (1) · brolucizumab (1) · salicylhydroxamic acid (1)
Asociación para Evitar la Ceguera en México (3) · Biocad (1) · Imperial College London (1) · Novartis Pharmaceuticals (1) · OPKO Health, Inc. (1) · St. Erik Eye Hospital (1) · University of California, San Francisco (1)
Mexico (3) · Brazil (1) · Russia (1) · Sweden (1) · United States (1)
Anders Kvanta, MD, PhD (1) · Catherine Psaras, BA (1) · Daniel Chao, MD, PhD (1) · Griselda Alvarez, Fellow (1) · Jay Stewart, MD (1) · Naveed Shams, MD (1) · Richard Cheong-Leen (1) · Rosa M Romero, MD (1) · Stefan Seregard, MD, PhD (1) · Victoria Cubas-Lorenzo, MD (1)