33 unknown. 33 Phase 1, 22 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 33 | Unknown 33 |
| Phase 2 | 22 | Unknown 22 |
Follow Retinal Degeneration: new trials by email Literature Review of Retinal Degeneration trials Research Report on Retinal Degeneration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| BF844 Safety and Pharmacokinetic Study in Healthy Volunteers BF844 - Usher Syndrome Type 3 | Phase 1 | Unknown | EyeXCel Pty. Ltd. | 76 | 2024-09-09 | 2024-09-19 |
| Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration VOY-101 - Age-related Macular Degeneration, Geographic Atrophy | Phase 1 / Phase 2 | Unknown | Perceive Biotherapeutics, Inc. | 45 | 2022-11-17 | 2024-04-11 |
| Treatment of Age-related Macular Degeneration Using Retinal Stem and Progenitor Cells Cultured retinal stem and progenitor cells, Standard treatment according to the clinical protocols - Age-Related Macular Degeneration | Phase 1 / Phase 2 | Unknown | Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | 20 | 2022-03-01 | 2022-09-14 |
| Possible Effects of Supplement Therapy With Oral Phenolics on Cluster of Differentiation 163 (CD-163) Biomarker of Patients With Age-related Macular Degeneration Oral intake of medication, Placebo - Age Related Macular Degeneration | Phase 1 | Unknown | Shahid Beheshti University of Medical Sciences | 80 | 2021-07-28 | 2021-08-16 |
| Single Ascending Dose Study in Participants With LCA10 EDIT-101 - Leber Congenital Amaurosis 10, Inherited Retinal Dystrophies | Phase 1 / Phase 2 | Unknown | Editas Medicine, Inc. | 34 | 2019-09-26 | 2022-12-05 |
| Episcleral Dexamethasone for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole Episcleral Dexamethasone - Macular Edema, Radiation Retinopathy | Phase 1 | Unknown | Targeted Therapy Technologies, LLC | 2 | 2019-09-01 | 2023-11-24 |
| Minocycline Treatment for Cystoid Macular Edema minocycline - Minocycline, Cystoid Macular Edema | Phase 1 / Phase 2 | Unknown | Sun Yat-sen University | 5 | 2019-01-01 | 2023-04-19 |
| Stem Cells Therapy in Degenerative Diseases of the Retina Stem/progenitor cells transplantation - Retinal Degeneration, Retinitis Pigmentosa | Phase 1 | Unknown | Pomeranian Medical University Szczecin | 30 | 2018-12-13 | 2018-12-17 |
| The Safety and Tolerability of Sub-retinal Transplantation of SCNT-hES-RPE Cells in Patients With Advanced Dry AMD SCNT-hES-RPE Cells - Dry Age Related Macular Degeneration | Phase 1 | Unknown | CHA University | 3 | 2016-05-01 | 2017-10-09 |
| Study of Subretinal Implantation of Human Embryonic Stem Cell-Derived RPE Cells in Advanced Dry AMD CPCB-RPE1 - Dry Macular Degeneration, Geographic Atrophy | Phase 1 / Phase 2 | Unknown | Regenerative Patch Technologies, LLC | 16 | 2016-02-16 | 2020-05-29 |
| Safety and Tolerability of hRPC in Retinitis Pigmentosa hRPC - Retinitis Pigmentosa | Phase 1 / Phase 2 | Unknown | ReNeuron Limited | 29 | 2015-12-01 | 2023-07-06 |
| Evaluating RXI-109 to Reduce the Progression of Subretinal Fibrosis in Subjects With NVAMD RXI-109 - Age-related Macular Degeneration, Subfoveal Choroidal Neovascularization | Phase 1 / Phase 2 | Unknown | RXi Pharmaceuticals, Corp. | 9 | 2015-11-01 | 2018-02-26 |
| Intravitreal Aflibercept Injection for Symptomatic Macular Edema From Retinal Artery Macroaneurysms aflibercept - Macular Edema, Retinal Artery Macroaneurysm | Phase 1 | Unknown | Kamal Kishore, MD | 6 | 2015-05-14 | 2019-08-08 |
| Clinical Study of Subretinal Transplantation of Human Embryo Stem Cell Derived Retinal Pigment Epitheliums in Treatment of Macular Degeneration Diseases Subretinal transplantation - Macular Degeneration, Stargardt's Macular Dystrophy | Phase 1 / Phase 2 | Unknown | Southwest Hospital, China | 15 | 2015-05-01 | 2018-01-31 |
| Visual Outcomes and the Predictive Factors in Chinese Patients With Diabetic Macular Edema Treated With Ranibizumab Ranibizumab - Diabetic Macular Edema | Phase 1 / Phase 2 | Unknown | Sun Yat-sen University | 100 | 2015-01-01 | 2019-06-04 |
| Clinical Study to Evaluate Safety and Efficacy of BMMNC in Retinitis Pigmentosa BMMNCs - Retinitis Pigmentosa | Phase 1 / Phase 2 | Unknown | Chaitanya Hospital, Pune | 15 | 2014-09-01 | 2014-09-17 |
| Ziv-aflibercept in Eyes With Retinal Diseases and Poor Vision-phase I ziv-aflibercept drug - Age Related Macular Degeneration, Central Retinal Vein Occlusion | Phase 1 | Unknown | Rafic Hariri University Hospital | 100 | 2014-06-01 | 2014-06-25 |
| Effectiveness and Safety of Adipose-Derived Regenerative Cells for Treatment of Glaucomatous Neurodegeneration Subtenon administration of autologous ADRC, Liposuction, ADRC isolation - Retinal Degeneration, Primary Open-Angle Glaucoma | Phase 1 / Phase 2 | Unknown | Central Clinical Hospital w/Outpatient Health Center of Business Administration for the President of Russian Federation | 16 | 2014-05-01 | 2017-07-21 |
| Autologous Bone Marrow-Derived CD34+, CD133+, and CD271+ Stem Cell Transplantation for Retinitis Pigmentosa Stem Cell Transplantation - Retinitis Pigmentosa | Phase 1 / Phase 2 | Unknown | Stem Cells Arabia | 50 | 2014-04-01 | 2020-03-17 |
| Safety Study of Use of Autologous Bone Marrow Derived Stem Cell in Treatment of Age Related Macular Degeneration autologous bone marrow derived stem cells - Age Related Macular Degeneration | Phase 1 / Phase 2 | Unknown | Al-Azhar University | 1 | 2013-03-01 | 2013-12-24 |
Showing 20 of 33. Sign in to see all of them.
Macular Degeneration (17) · Macular Edema (8) · Retinitis Pigmentosa (5) · Diabetes Mellitus (3) · Retinal Diseases (3) · Eye Diseases (2) · Genetic Diseases, Inborn (2) · Geographic Atrophy (2) · Retinal Vein Occlusion (2) · Stargardt Disease (2) · Cataract (1) · Choroidal Neovascularization (1) · Congenital Abnormalities (1) · Diabetic Retinopathy (1)
Eye Diseases (31) · Retinal Diseases (30) · Eye Diseases, Hereditary (9) · Macular Degeneration (9) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (8) · Genetic Diseases, Inborn (6) · Retinal Dystrophies (6) · Endocrine System Diseases (4) · Cardiovascular Diseases (3) · Glucose Metabolism Disorders (3) · Metabolic Diseases (3) · Nervous System Diseases (3) · Nutritional and Metabolic Diseases (3) · Pathological Conditions, Signs and Symptoms (3)
Triamcinolone Acetonide (2) · aflibercept (2) · Bevacizumab (1) · Diclofenac (1) · Infliximab (1) · Lipectomy (1) · Lutein (1) · Minocycline (1) · Ranibizumab (1) · Stem Cell Transplantation (1) · Triamcinolone (1) · Zeaxanthins (1)
Catholic University of the Sacred Heart (2) · Shahid Beheshti University of Medical Sciences (2) · Sun Yat-sen University (2) · University of Sao Paulo (2) · Al-Azhar University (1) · CHA University (1) · Central Clinical Hospital w/Outpatient Health Center of Business Administration for the President of Russian Federation (1) · Chaitanya Hospital, Pune (1) · Editas Medicine, Inc. (1) · EyeXCel Pty. Ltd. (1) · Icahn School of Medicine at Mount Sinai (1) · Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus (1) · Kamal Kishore, MD (1) · NeoVista (1) · Ora Bio Ltd. (1)
United States (11) · China (4) · Israel (3) · Brazil (2) · Iran (2) · Italy (2) · United Kingdom (2) · Australia (1) · Belarus (1) · Egypt (1) · India (1) · Jordan (1) · Lebanon (1) · Mexico (1) · Poland (1)
Ahmad Mansour, MD (1) · Alina K Drakon, MD (1) · Benedetto Falsini, M.D. (1) · Benedetto Falsini, MD (1) · Benedict Tan, MBBS, FRACP (1) · Chenjin Jin, ph.D. (1) · Denis O'Shaughnessy, Ph.D. (1) · Farzin Forooghian, MD (1) · Gerrit Dispersyn (1) · Ilya I Eremin, MD, PhD (1) · Itay Chovers, MD (1) · Jane Lebkowski, Ph.D. (1)
PMID 36912792, PMID 19906082, PMID 20688744, PMID 22895887, PMID 25677668, PMID 31618812, PMID 32539744, PMID 32573764, PMID 33497524, PMID 34629400, PMID 37702300, PMID 38709228, PMID 40020685