11 completed, 10 unknown, 7 terminated, 1 enrolling by invitation. 8 Not applicable, 7 Phase 3, 5 Phase 1, 5 Phase 2, 1 Phase 4.
Follow Respiratory Tract Disease: new trials by email Literature Review of Respiratory Tract Disease trials Research Report on Respiratory Tract Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Antibiotic Stewardship in AECOPD Through CRP-Guided Management The intervention (CRP-guided) group - Acute Exacerbation of COPD, Lung Diseases | Not applicable | Unknown | The University of Hong Kong | 1184 | 2022-09-01 | 2022-05-23 |
| Prospective, Observational Study of Wellinks Effect on COPD Hospital Readmissions Wellinks - COPD, Respiratory Tract Disease | Unknown | Convexity Scientific Inc | 150 | 2022-07-05 | 2023-11-03 | |
| (Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations BLU-451, Carboplatin, Pemetrexed - Lung Neoplasm Malignant, Carcinoma, Non-Small-Cell Lung | Phase 1 | Terminated | Blueprint Medicines Corporation | 103 | 2022-03-04 | 2025-02-10 |
| Recording of Multiple Nights Using a New Contactless Device (Sleepiz One Connect) in Obstructive Sleep Apnea Sleepiz One Connect - Obstructive Sleep Apnea, Sleep Apnea | Completed | Samuel Tschopp | 25 | 2021-12-01 | 2023-10-10 | |
| Partially Hydrolyzed Guar Gum (PHGG) for Amelioration of Chronic Obstructive Pulmonary Disease (COPD) Partially Hydrolyzed Guar Gum (PHGG) - COPD, Microbial Colonization | Not applicable | Unknown | Fu Jen Catholic University Hospital | 60 | 2021-11-01 | 2021-11-19 |
| (SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC BLU-945, osimertinib - Lung Neoplasms, Carcinoma, Non-Small-Cell Lung | Phase 1 | Terminated | Blueprint Medicines Corporation | 177 | 2021-06-29 | 2025-02-10 |
| Comparison Between Natural Sleep Endoscopy and Drug-induced Sleep Endoscopy in Patients With Obstructive Sleep Apnea Drug-induced sleep endoscopy, Natural sleep endoscopy - Sleep Apnea, Obstructive, Sleep Apnea | Not applicable | Unknown | ethisch.comite@uza.be | 40 | 2021-03-30 | 2021-07-26 |
| Complete Shielding of Multivitamins to Reduce Toxic Peroxides in the Parenteral Nutrition: A Pilot Study Photo-protection, Standard Care - Parenteral Nutrition, Infant, Premature, Diseases | Not applicable | Completed | St. Justine's Hospital | 35 | 2020-11-23 | 2022-10-31 |
| SILtuximab in Viral ARds (SILVAR) Study Siltuximab, Normal Saline - Acute Respiratory Distress Syndrome, Lung Diseases | Phase 3 | Terminated | RECORDATI GROUP | 555 | 2020-11-13 | 2021-04-19 |
| Natural Killer Cell (CYNK-001) Infusions in Adults With COVID-19 CYNK-001 - Coronavirus, Coronavirus Infection | Phase 1 / Phase 2 | Terminated | Celularity Incorporated | 7 | 2020-09-02 | 2026-06-26 |
| Houston "Breathe Easy" Healthy Homes-Based Model for Multifamily Rental Communities Exposure-Reduction Intervention - Asthma, Respiratory Tract Disease | Not applicable | Unknown | Baylor College of Medicine | 28 | 2020-08-27 | 2022-06-06 |
| A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) Pralsetinib, Carboplatin, Cisplatin - RET-fusion Non Small Cell Lung Cancer, Lung Neoplasm | Phase 3 | Terminated | Hoffmann-La Roche | 223 | 2020-07-24 | 2026-03-05 |
| Comparison of Tocilizumab Plus Dexamethasone vs. Dexamethasone for Patients With Covid-19 Tocilizumab, Dexamethasone - Coronavirus Infection, SARS (Severe Acute Respiratory Syndrome) | Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 453 | 2020-07-16 | 2024-05-31 |
| Prevalence and Risk Factors of COVID-19 in the Upper Silesian Agglomeration IgM and IgG antibodies assay - Covid19, Respiratory Tract Infections | Unknown | Medical University of Silesia | 6000 | 2020-06-22 | 2020-11-17 | |
| Study of Clinical and Immune Severity Profiles of Patients Infected With SARS-Cov2 (COVID-19) Respiratory Tract Infections, Respiratory Tract Disease | Unknown | Direction Centrale du Service de Santé des Armées | 100 | 2020-04-21 | 2021-03-09 | |
| A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension Ralinepag - PAH, Pulmonary Hypertension | Phase 3 | Enrolling by invitation | United Therapeutics | 1000 | 2019-09-23 | 2026-10-06 |
| A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients Ralinepag, Placebo - PAH, Pulmonary Hypertension | Phase 3 | Completed | United Therapeutics | 687 | 2019-01-24 | 2026-06-16 |
| Evaluation of the Respiratory Function in Renal Transplanted Children pulmonary function - Respiratory Tract Disease, Kidney Transplantation | Not applicable | Unknown | Nantes University Hospital | 385 | 2018-07-16 | 2021-06-18 |
| Comparison of Two Telemonitoring Auto-titrating Modalities in OSA Patients EZ START Titration, APAP Titration - Apnea, Sleep Apnea Syndromes | Not applicable | Completed | Basque Health Service | 50 | 2018-04-01 | 2019-01-09 |
| Centralized Reminder Recall - Flu RCT2 R/R - Autodialers, R/R - Texting, R/R - mailed postcard - Influenza, Human, Orthomyxoviridae Infections | Not applicable | Completed | University of California, Los Angeles | 70190 | 2017-10-18 | 2019-06-05 |
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Respiratory Tract Diseases (29) · Lung Diseases (15) · Respiratory Tract Infections (7) · Carcinoma, Bronchogenic (6) · Carcinoma, Non-Small-Cell Lung (6) · Lung Neoplasms (6) · Bronchial Neoplasms (5) · Neoplasms by Site (5) · RNA Virus Infections (5) · Respiratory Tract Neoplasms (5) · Thoracic Neoplasms (5) · Virus Diseases (5) · Adenocarcinoma (4) · Carcinoma (4) · Neoplasms (4)
Pathological Conditions, Signs and Symptoms (10) · Infections (9) · Pathologic Processes (7) · Bronchial Diseases (6) · Disease Attributes (4) · Nervous System Diseases (4) · Signs and Symptoms (4) · Chronic Disease (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Neoplasms, Glandular and Epithelial (3) · Neurologic Manifestations (3) · Respiratory Tract Infections (3) · Brain Diseases (2) · Central Nervous System Diseases (2) · Dyssomnias (2)
Carboplatin (3) · Pemetrexed (3) · camrelizumab (2) · pralsetinib (2) · ralinepag (2) · 130-nm albumin-bound paclitaxel (1) · Cisplatin (1) · Dexamethasone (1) · Gemcitabine (1) · Influenza Vaccines (1) · Ketamine (1) · Observation (1) · Paclitaxel (1) · Population Groups (1) · Saline Solution (1)
Blueprint Medicines Corporation (2) · Hoffmann-La Roche (2) · Jiangsu HengRui Medicine Co., Ltd. (2) · United Therapeutics (2) · Abt Associates (1) · Assistance Publique - Hôpitaux de Paris (1) · Basque Health Service (1) · Baylor College of Medicine (1) · Bracane Company (1) · Celularity Incorporated (1) · Convexity Scientific Inc (1) · Direction Centrale du Service de Santé des Armées (1) · Fu Jen Catholic University Hospital (1) · Hospital de Clinicas de Porto Alegre (1) · Medicago (1)
United States (11) · France (7) · Canada (6) · South Korea (6) · Spain (6) · Taiwan (6) · United Kingdom (6) · Belgium (5) · China (5) · Netherlands (5) · Germany (4) · Italy (4) · Poland (4) · Singapore (4) · Argentina (3)
Wei Shi, MD (2) · Chia-Chen Lu, PhD (1) · Corey Casper, MD MPH (1) · Francisco E Martinez, MD (1) · Ibrahim Mohamed, M.D.,Ph.D. (1) · Jan E Zejda, Prof (1) · Jefferson Piva (1) · Kirk Allan (1) · Maria Theresa Basco, MD, MPH (1) · Mark Thompson, PhD (1) · Mikel Azpiazu, MD (1) · Olivier Vanderveken, MD, PhD (1)
PMID 30400834, PMID 31291514, PMID 32446470, PMID 33347829, PMID 33581920, PMID 34118197, PMID 34118198, PMID 34668977, PMID 34950101, PMID 35350097, PMID 35715405, PMID 35936702, PMID 35962206, PMID 36194670, PMID 36331328, PMID 36646210, PMID 37282666, PMID 37916501, PMID 37934000, PMID 38009200, PMID 38415722, PMID 39608979, PMID 40639400, PMID 41886723, PMID 42520828
2016 (1), 2019 (1), 2023 (1), R01AI114903 (1)