666 completed, 65 terminated, 45 withdrawn, 43 unknown. 892 Phase 2, 74 Phase 1, 71 Phase 3.
Follow Respiratory Hypersensitivity: new trials by email Literature Review of Respiratory Hypersensitivity trials Research Report on Respiratory Hypersensitivity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Linvemastat in Patients With Partially Controlled Asthma (syMMPonia) linvemastat, Placebo - Asthma (Diagnosis), Pulmonary Function | Phase 2 | Not yet recruiting | Foresee Pharmaceuticals Co., Ltd. | 135 | 2027-03-01 | 2026-07-20 |
| Preventing Childhood Asthma Using Prophylactic House Dust Mite Allergen Immunotherapy HDM sublingual Immunotherapy, Placebo - Asthma, Allergy | Phase 2 | Withdrawn | Boston Children's Hospital | 2027-02-01 | 2024-11-26 | |
| Efficacy and Safety of Slow Release Dehydroepiandrosterone (DHEA ) Slow Release DHEA, Placebo - Asthma | Phase 2 | Not yet recruiting | Indiana University | 30 | 2027-01-01 | 2026-02-27 |
| Nebulized Ketamine for Severe Asthma Attacks in Children Ketamine (1 mg/kg), Placebo - Asthma Acute, Exacerbation of Allergic Asthma | Phase 2 | Not yet recruiting | Sultan Qaboos University | 60 | 2027-01-01 | 2026-07-27 |
| Ginger's Therapeutic Potential in Asthma Ginger Extract, Placebo - Asthma | Phase 2 | Not yet recruiting | Emily DiMango, MD | 32 | 2026-11-01 | 2026-08-28 |
| A Study of JNJ-95597528 in Participants With Inadequately Controlled Moderate to Severe Asthma JNJ-95597528, Placebo - Asthma | Phase 2 | Recruiting | Janssen Research & Development, LLC | 440 | 2026-10-05 | 2026-11-03 |
| Study of CM512 Injection in Patients With Perennial Allergic Rhinitis on Background Therapy CM512, Placebo - Perennial Allergic Rhinitis (PAR) | Phase 2 | Not yet recruiting | Beijing Keymed Biosciences Co., Ltd. | 200 | 2026-10-01 | 2026-10-22 |
| Rademikibart IV for Acute Asthma and COPD Exacerbation Rademikibart - Asthma Acute, COPD Exacerbation Acute | Phase 2 | Recruiting | Connect Biopharm LLC | 40 | 2026-08-21 | 2026-11-04 |
| Pediatric Asthma Trial of Corticosteroid Heterogeneity (PATCH): Trial of Dexamethasone Versus Methylprednisolone for Pediatric Critical Asthma Dexamethasone (0.6mg/kg; Max 16mg) Once Daily, Dexamethasone (0.25 mg/kg/dose, Max dose 16mg) every 6-hours, Methylprednisolone - Asthma (Diagnosis) | Phase 2 | Recruiting | Johns Hopkins All Children's Hospital | 159 | 2026-08-01 | 2026-08-12 |
| A Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe Asthma Frevecitinib, Placebo - Severe Asthma | Phase 2 | Recruiting | Kinaset Therapeutics Inc | 512 | 2026-07-16 | 2026-07-28 |
| A Long-term Study of KT-621 Administered Orally to Participants With Asthma Previously Enrolled in a KT-621 Asthma Study KT-621 - Asthma (Diagnosis) | Phase 2 | Recruiting | Kymera Therapeutics, Inc. | 264 | 2026-06-25 | 2026-10-07 |
| Study of Stapokibart Injection in Adolescent Subjects With Seasonal Allergic Rhinitis (SAR) Stapokibart injection - Seasonal Allergic Rhinitis (SAR) | Phase 2 | Not yet recruiting | Chengdu Kangnuoxing Biopharma,Inc. | 15 | 2026-06-01 | 2026-06-01 |
| Nebulized Ketamine Plus Standard Care vs. Standard Care Alone in Moderate to Severe Asthma Exacerbations Nebulized ketamine (0.5 mg/kg in normal saline to a total volume of 5ml) plus standard asthma excaerbationcare, Placebo nebulization (5 mL normal saline) plus standard asthma care - Asthma Acute, Asthma Attack | Phase 2 | Recruiting | Oman Medical Speciality Board | 100 | 2026-05-30 | 2026-10-19 |
| Efficacy of L-menthol on Breathlessness in Asthma L-menthol, Placebo - Asthma | Phase 2 | Recruiting | Region Skane | 20 | 2026-05-07 | 2026-08-19 |
| PollenVax Subcutaneous Immunotherapy for Mugwort Pollen-Induced Allergic Rhinitis Recombinant Artemisia vulgaris allergen Art v 1 with Montanide ISA-51 adjuvant, Montanide ISA-51 placebo emulsion - Rhinitis Allergic | Phase 2 | Recruiting | Kazakh National Agrarian University | 138 | 2026-05-01 | 2026-06-29 |
| A Phase II Study to Investigate Lung Function With 2 Different Doses of Inhaled Glycopyrronium Taken With BFF Compared to BFF in Participants of 4 to Less Than 12 Years of Age With Asthma GP MDI, BFF MDI, Placebo MDI - Asthma | Phase 2 | Recruiting | AstraZeneca | 69 | 2026-04-14 | 2026-10-13 |
| Trial of JYB1904 Injection in Patients With Perennial Allergic Rhinitis JYB1904, Placebo+JYB1904 - Perennial Allergic Rhinitis | Phase 2 | Not yet recruiting | Jemincare | 135 | 2026-04-01 | 2026-03-09 |
| Study of Inhaled ARO-RAGE in Allergen-induced Mild Asthma ARO-RAGE, Placebo - Asthma | Phase 2 | Recruiting | Arrowhead Pharmaceuticals | 36 | 2026-03-30 | 2026-10-01 |
| Clinical Study on TQH2722 Injection Combined With Background Therapy for Seasonal Allergic Rhinitis TQH2722 injection - Seasonal Allergic Rhinitis | Phase 2 | Recruiting | Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. | 300 | 2026-03-19 | 2026-03-27 |
| VENTURI (VENTilation Using Respiratory Imaging) Beclomethasone Dipropionate/Formoterol Fumarate/Glycopyrrolate pMDI, Fluticasone Furoate/Umeclidinium/Vilanterol 100 MCG/1 ACTUATION-62.5 MCG/1 ACTUATION-25 MCG/1 ACTUATION Inhalation Powder - Asthma | Phase 2 | Recruiting | University of Alabama at Birmingham | 20 | 2026-03-15 | 2026-04-13 |
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Asthma (667) · Rhinitis, Allergic (119) · Rhinitis, Allergic, Seasonal (106) · Hypersensitivity (53) · Pulmonary Disease, Chronic Obstructive (30) · Rhinitis (27) · Rhinitis, Allergic, Perennial (19) · Respiratory Sounds (16) · Obesity (15) · Aspergillosis, Allergic Bronchopulmonary (13) · Lung Diseases (13) · Respiratory Tract Diseases (13) · Dust Mite Allergy (12) · Inflammation (12) · Dyspnea (11)
Hypersensitivity, Immediate (888) · Immune System Diseases (888) · Respiratory Tract Diseases (879) · Hypersensitivity (839) · Lung Diseases (672) · Bronchial Diseases (670) · Lung Diseases, Obstructive (663) · Nose Diseases (232) · Otorhinolaryngologic Diseases (232) · Rhinitis (202) · Pathological Conditions, Signs and Symptoms (108) · Rhinitis, Allergic (105) · Pathologic Processes (59) · Infections (56)
Fluticasone (33) · montelukast (31) · Albuterol (29) · Formoterol Fumarate (29) · Budesonide (20) · Beclomethasone (17) · Mometasone Furoate (16) · Omalizumab (13) · fluticasone furoate (11) · Salmeterol Xinafoate (10) · indacaterol (10) · Fluticasone-Salmeterol Drug Combination (9) · Saline Solution (9) · Tiotropium Bromide (9) · dupilumab (9)
GlaxoSmithKline (71) · Novartis Pharmaceuticals (42) · AstraZeneca (37) · Boehringer Ingelheim (26) · Chiesi Farmaceutici S.p.A. (24) · Merck Sharp & Dohme LLC (14) · Novartis (13) · MedImmune LLC (12) · National Institute of Allergy and Infectious Diseases (NIAID) (11) · Pfizer (11) · Sanofi (11) · Teva Branded Pharmaceutical Products R&D, Inc. (11) · Amphastar Pharmaceuticals, Inc. (10) · Genentech, Inc. (10) · Organon and Co (9)
United States (372) · Germany (156) · United Kingdom (137) · Canada (127) · Poland (100) · China (58) · Bulgaria (53) · France (52) · Hungary (52) · Argentina (50) · Russia (48) · South Africa (45) · Spain (45) · Belgium (40) · South Korea (40)
Dave Singh, MD (8) · Luo Zhang (6) · Fernando Holguin, MD, MPH (4)
PMID 27881132, PMID 39393433, PMID 36472162, PMID 19001265, PMID 19748656, PMID 21356110, PMID 24010736, PMID 24184147, PMID 25445859, PMID 26001563, PMID 26283085, PMID 26704701, PMID 28639856, PMID 28758192, PMID 29656145, PMID 33217063, PMID 33305842, PMID 34089147, PMID 34379802, PMID 36253275, PMID 39035788, PMID 11398072, PMID 12668793, PMID 14619332, PMID 14674933, PMID 15313870, PMID 15461603, PMID 15516669, PMID 15750716, PMID 15898976, PMID 16164444, PMID 16387596, PMID 16930249, PMID 17021320, PMID 17631952, PMID 17950857, PMID 18244953, PMID 18331513, PMID 18403223, PMID 18566548, PMID 18595980, PMID 18699936, PMID 18787222, PMID 18946234, PMID 19136369, PMID 19196814, PMID 19264687, PMID 19614621, PMID 19656525, PMID 19680119
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