24 completed. 24 Phase 2, 5 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 24 | Completed 24 |
| Phase 1 | 5 | Completed 5 |
Follow Relapsing Chronic Myelogenous Leukemia: new trials by email Literature Review of Relapsing Chronic Myelogenous Leukemia trials Research Report on Relapsing Chronic Myelogenous Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies vorinostat, tacrolimus, cyclosporine - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission | Phase 2 | Completed | National Cancer Institute (NCI) | 12 | 2013-06-01 | 2018-07-24 |
| Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies therapeutic allogeneic lymphocytes, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Phase 2 | Completed | University of Chicago | 77 | 2013-04-04 | 2019-08-07 |
| Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies cyclophosphamide, cyclosporine, peripheral blood stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 43 | 2011-09-01 | 2017-05-19 |
| Infusion of Off-the-Shelf Expanded Cord Blood Cells to Augment Cord Blood Transplant in Patients With Hematologic Malignancies umbilical cord blood transplantation, fludarabine phosphate, cyclophosphamide - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission | Phase 2 | Completed | Nohla Therapeutics, Inc. | 15 | 2010-08-01 | 2019-03-05 |
| Nilotinib and Imatinib Mesylate After Donor Stem Cell Transplant in Treating Patients With ALL or CML nilotinib, imatinib mesylate, pharmacological study - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 40 | 2008-08-14 | 2017-08-10 |
| Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant ondansetron, survey administration, management of therapy complications - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 49 | 2008-08-08 | 2017-05-23 |
| Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies double-unit umbilical cord blood transplantation, cytogenetic analysis, bone marrow aspiration - Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Case Comprehensive Cancer Center | 14 | 2007-09-01 | 2019-01-23 |
| Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer beclomethasone dipropionate, placebo, tacrolimus - Hematopoietic/Lymphoid Cancer, Accelerated Phase Chronic Myelogenous Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 140 | 2007-04-01 | 2021-02-03 |
| 3-AP and Fludarabine in Treating Patients With Myeloproliferative Disorders, Chronic Myelomonocytic Leukemia, or Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia fludarabine phosphate, triapine, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative | Phase 2 | Completed | National Cancer Institute (NCI) | 35 | 2006-08-01 | 2015-01-06 |
| Etanercept in Treating Young Patients With Idiopathic Pneumonia Syndrome After Undergoing a Donor Stem Cell Transplant etanercept, methylprednisolone - Accelerated Phase Chronic Myelogenous Leukemia, Blastic Phase Chronic Myelogenous Leukemia | Phase 2 | Completed | Children's Oncology Group | 39 | 2006-04-01 | 2017-09-29 |
| Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer alemtuzumab, total-body irradiation, fludarabine phosphate - Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 12 | 2005-03-01 | 2017-05-30 |
| Fludarabine Phosphate, Busulfan, and Anti-Thymocyte Globulin Followed By Donor Peripheral Blood Stem Cell Transplant, Tacrolimus, and Methotrexate in Treating Patients With Myeloid Malignancies fludarabine phosphate, busulfan, anti-thymocyte globulin - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 23 | 2004-09-01 | 2016-05-06 |
| CCI-779 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, or Chronic Myelogenous Leukemia in Blastic Phase temsirolimus, laboratory biomarker analysis - Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Phase 2 | Completed | National Cancer Institute (NCI) | 74 | 2004-04-01 | 2013-01-23 |
| Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic Cancer fludarabine phosphate, total-body irradiation, mycophenolate mofetil - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 150 | 2004-04-01 | 2020-01-29 |
| Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant fludarabine phosphate, total-body irradiation, nonmyeloablative allogeneic hematopoietic stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 37 | 2003-09-01 | 2020-01-18 |
| Imatinib Mesylate and Decitabine in Treating Patients With Chronic Myelogenous Leukemia imatinib mesylate, decitabine, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Blastic Phase Chronic Myelogenous Leukemia | Phase 2 | Completed | National Cancer Institute (NCI) | 80 | 2003-01-01 | 2013-01-23 |
| Oblimersen and Imatinib Mesylate in Treating Patients With Chronic Myelogenous Leukemia oblimersen sodium, imatinib mesylate, laboratory biomarker analysis - Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Chronic Phase Chronic Myelogenous Leukemia | Phase 2 | Completed | National Cancer Institute (NCI) | 43 | 2002-11-01 | 2013-06-04 |
| Biological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leukemia, or Acute Lymphoblastic Leukemia Who Are Undergoing Stem Cell Transplantation therapeutic allogeneic lymphocytes, aldesleukin, peripheral blood stem cell transplantation - Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 37 | 2002-09-01 | 2017-03-29 |
| Haploidentical Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancer cyclophosphamide, fludarabine phosphate, tacrolimus - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 53 | 2002-01-01 | 2017-05-17 |
| Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies alemtuzumab, fludarabine phosphate, total-body irradiation - Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q) | Phase 2 | Completed | Fred Hutchinson Cancer Center | 60 | 2001-11-01 | 2020-01-29 |
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Leukemia, Myeloid, Chronic-Phase (18) · Leukemia, Myeloid, Accelerated Phase (16) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (16) · Congenital Abnormalities (14) · Leukemia, Myeloid, Acute (14) · Blast Crisis (13) · Burkitt Lymphoma (13) · Leukemia, Lymphocytic, Chronic, B-Cell (12) · Lymphoma, B-Cell, Marginal Zone (12) · Lymphoma, Follicular (12) · Lymphoma, Large B-Cell, Diffuse (12) · Lymphoma, Large-Cell, Immunoblastic (12) · Lymphoma, Mantle-Cell (12) · Lymphoma, Non-Hodgkin (12) · Hodgkin Disease (11)
Bone Marrow Diseases (24) · Chronic Disease (24) · Disease Attributes (24) · Hematologic Diseases (24) · Hemic and Lymphatic Diseases (24) · Leukemia (24) · Leukemia, Myeloid (24) · Neoplasms (24) · Neoplasms by Histologic Type (24) · Pathologic Processes (24) · Pathological Conditions, Signs and Symptoms (24) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (17) · Immune System Diseases (16) · Immunoproliferative Disorders (16) · Leukemia, Lymphoid (16)
fludarabine phosphate (9) · Cyclosporine (8) · Mycophenolic Acid (7) · Peripheral Blood Stem Cell Transplantation (7) · Whole-Body Irradiation (7) · Cyclophosphamide (5) · Tacrolimus (5) · Busulfan (4) · Imatinib Mesylate (4) · Methotrexate (4) · Transplantation (4) · merphos (4) · Methylprednisolone (3) · Methylprednisolone Acetate (3) · Methylprednisolone Hemisuccinate (3)
Fred Hutchinson Cancer Center (11) · National Cancer Institute (NCI) (8) · Case Comprehensive Cancer Center (2) · Children's Oncology Group (1) · Nohla Therapeutics, Inc. (1) · University of Chicago (1)
United States (24) · Italy (4) · Germany (1)
Brenda Sandmaier (3) · Brenda Cooper, MD (1) · Colleen Delaney (1) · David Maloney (1) · Francis Giles (1) · Gregory Yanik, MD (1) · H. Joachim Deeg (1) · Hillard Lazarus (1) · Hongtao Liu (1) · Jean-Pierre Issa (1) · Jorge Cortes (1) · Judith Karp (1) · Leona Holmberg (1) · Marco Mielcarek (1) · Meir Wetzler (1)
PMID 32499241, PMID 19900571, PMID 24362550, PMID 26764356, PMID 35445027
P30CA015704 (8), P01CA018029 (5), N01CM62202 (2), N01CM17003 (1), P01CA078902 (1), P01HL036444 (1), P30CA006973 (1), P30CA046592 (1), RC2HL101844 (1), U01CA070095 (1), U10CA031946 (1), U10CA098543 (1)